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  1. ...at least two carbon–carbon double bonds. The biologically formed double bond has a cis configu-rich in n-3 PUFAs associated with high seafood intake isIntroduction It is well-known that n-3 polyunsaturated fatty acids (PUFAs), especially eicosapentanoic acid (EPA, 20:5, n-3) and docosahexanoic acid (DHA...
  2. ...an intriguing lipoprotein that attracted the attention of biomedical community, mainly because of its important role in atheroprotection (Constantinou et al. 2015). Indeed, the inverse correlation between HDL cholesterol (HDL-C) levels and the risk for developing coronary heart disease (Gofman  et  al. 1954...
  3. ...at 4°C overnight with the primary antibody: anti-ACTB antibody 1/10,000 (Abcam), anti-UCP1 1/5000 (Abcam) and antibodies for Fatty Acid and Lipid Metabolism and Lipolysis Activation (8334, 8335 Cell Signaling Technology). After three washes, the membranes were probed with anti-mouse 680 and anti...
  4. ...the intracellular Acyl-CoA ester pool size (Mandrup et al. 1993), and synthesis of very long-chain fatty acids and sphingolipids (Gaigg et al. 2001). A spontaneous mutant mouse nm1054, cataloged at the Jackson Laboratory (Ohgami et  al. 2005a,b), was subsequently identified to also contain a mutation in the ACBP...
  5. ...glucocorticoid output Division of Biopharmaceutics, Cluster BioTherapeutics, Gorlaeus Laboratories, Leiden Academic Centre for profile provide the first in vivo evidence for a novel inhibitory role of the LDLR in the control Key Words " cholesterol " lipoprotein " LDL " receptor ). It is generally...
  6. ...of IKKB in fat-induced insulin resistance is time and tissue dependent and that hepatic insulin resistance induceddue to elevated circulating levels of free fatty acids (FFAs) kinase that is associated with http://.endocrinology-journals.org DOI: 10.1530/JOE-12-0214 2013 Society for Endocrinology Printed...
  7. ...mediated by lipoproteins (Tam et al. 2006, Takeo et al. 2008), and 2 h seems to be a short time for total cholesterol turnover through its diffusion to the albumin in the culture medium (Fig. 1B). This indicates that the 2-h of treatment with SIM did not cause alterations in the membrane ultrastructure...
  8. ...of cholesterol-lowering effect of such fatty acids. Thus, data suggest that n-3 PUFA effects on lipid metabolism are dependent on TH signaling in specific steps and, together with the marked upregulation of PPARa in liver of hypothyroid rats, suggests an important cross-talk between fatty acids and TH pathways...
  9. ...was the announcement that surgical removal of the ovaries from adult female rabbits caused uterine atrophy, which could be prevented by auto-transplantation of ovarian fragments 233 Correspondence should be addressed to S G Hillier Email [email protected] Key Words f cholesterol f estrogen f female reproduction f...
  10. ...The effects of dietary fatty acid composition in the post-sucking period ital a˚, S Car tolerance, and peripheral glucocorticoid (GC) metabolism in overfed neonatal rats. Rat litters were adjusted to a litter size groups compared with standard chow counterparts, whereas high-fat feeding increased...
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