The effects of intensive, long-term treadmill running on reproductive hormones, hypothalamus–pituitary–testis axis, and semen quality: a randomized controlled study

  1. Ali Asgar Kolahi2
  1. Urology and Nephrology Research Center, Shahid Beheshti University (MC), PO Box 19395-1849, Tehran, Iran1Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Aja University of Medical Sciences, 195 698-9333 Tehran, Iran2Department of Health and Community Medicine, Faculty of Medicine, Shahid Beheshti University (MC), 158 684-4139 Tehran, Iran
  1. (Correspondence should be addressed to M R Safarinejad; Email: safarinejad{at}unrc.ir)
  1. Figure 1

    Study design.

  2. Figure 2

    The participant flow diagram.

  3. Figure 3

    (A–D) Semen parameters during running and recovery periods. All data are shown as mean. HIE, high-intensity exercise and MIE, moderate-intensity exercise.

  4. Figure 4

    (A–D) Serum hormones levels during running and recovery periods. All data are shown as mean. HIE, high-intensity exercise and MIE, moderate-intensity exercise.

  5. Figure 5

    (A, B) FSH and LH, and (C) testosterone responses of subjects to GnRH analog, and hCG, at the end of running and recovery phases. HIE, high-intensity exercise; MIE, moderate-intensity exercise; GnRH, gonadotropin-releasing hormone and hCG, human chorionic gonadotropin.

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