Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses

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   Figure 1

   TPOAb concentrations at the beginning of the study and 3 months after treatment with 200 mg l-selenomethionine/day (group S2) or placebo (group C). P values were calculated by Wilcoxon’s matched pairs, signed-ranks test.
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   Figure 2

   Dose-response curves of subgroups. Note the concordance in decrement rates in groups S2, S22 and S212, who received 200 mg l-selemethionine/day, and the decreased response in group S222. Rising serum concentrations of TPOAb in group S21 clearly confirms the ineffectiveness of 100 mg l-selemethionine/day.

• Society for Endocrinology