Figure 2
Current understanding of the molecular actions of GLIS3 in diabetes. This figure summarizes the pathways by which ablation, loss-of-function mutations or functional impairment of GLIS3 cause neonatal diabetes, as well as common T1D and T2D. See text for details. A full colour version of this figure is available at http://dx.doi.org/10.1530/JME-16-0232.