Searching journal content for articles similar to Cao et al. 23 (12): T199.

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  1. Thematic Review:
    • Kathryn E Ware,
    • Mariano A Garcia-Blanco,
    • Andrew J Armstrong,
    • and Scott M Dehm
    Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer Endocr Relat Cancer 21 (4) T87-T103, doi:10.1530/ERC-13-0470 first published on 23 May 2014
    ..." androgen receptor " splice variants " castration resistant prostate cancer " AR variants " metastasis " epithelial to mesenchymale rt o CaKathryn E Ware1, Mariano A Garcia-Blanco1,2, Andrew J Armstrong1,2 andBiologic and clinical sign androgen receptor varia castration resistant proscance of ts in te...
  2. Review:
    • Sangeeta Kumari,
    • Dhirodatta Senapati,
    • and Hannelore V Heemers
    Rationale for the development of alternative forms of androgen deprivation therapy Endocr Relat Cancer 24 (8) R275-R295, doi:10.1530/ERC-17-0121 first published on 31 May 2017
    ...) Abstract With few exceptions, the almost 30,000 prostate cancer deaths annually in the United States are due to failure of androgen deprivation therapy. Androgen deprivation therapy prevents ligand-activation of the androgen receptor. Despite initial remission after androgen deprivation therapy, prostate...
  3. Thematic Review:
    • Damien A Leach,
    • Sue M Powell,
    • and Charlotte L Bevan
    WOMEN IN CANCER THEMATIC REVIEW: New roles for nuclear receptors in prostate cancer Endocr Relat Cancer 23 (11) T85-T108, doi:10.1530/ERC-16-0319 first published on 19 September 2016
    ...roles in pathophysiology of prostate cancer. Steroid receptors Androgen receptor (AR or NR3C4) Tumours not cured by surgery or radiotherapy are treated by blocking the action of AR. However, despite this, it has only been since the mid-90s that we have become aware of the importance of androgen...
  4. Review:
    • Alan P Lombard and
    • Maria Mudryj
    The emerging role of the androgen receptor in bladder cancer Endocr Relat Cancer 22 (5) R265-R277, doi:10.1530/ERC-15-0209 first published on 30 July 2015
    .... Recent studies suggest that there is a higher than expected association between prostate cancer and bladder cancer (Marcinkiewicz et al. 2012). This suggests that AR signaling may be one DHT P P HSP HSP STAT3 MAPK RAS IL IL-R GF RTK AKTSRC Review A P Lombard and M Mudryj Androgen receptor in bladder...
  5. Review:
    • Tracy Proverbs-Singh,
    • Jarett L Feldman,
    • Michael J Morris,
    • Karen A Autio,
    • and Tiffany A Traina
    Targeting the androgen receptor in prostate and breast cancer: several new agents in development Endocr Relat Cancer 22 (3) R87-R106, doi:10.1530/ERC-14-0543 first published on 26 February 2015
    ...are important for normal prostate architecture, homeostasis, AR protein N-terminal domain DNA-bind Zn++ NH2– Figure 1 Androgen receptor structure.X chromosomeand physiological function. In prostate cancer (PCa) cells, expression of these genes leads to the proliferation and survival of tumor cells. In breast...
  6. Thematic Review:
    • Muhammed H Rahaman,
    • Malika Kumarasiri,
    • Laychiluh B Mekonnen,
    • Mingfeng Yu,
    • Sarah Diab,
    • Hugo Albrecht,
    • Robert W Milne,
    • and Shudong Wang
    Targeting CDK9: a promising therapeutic opportunity in prostate cancer Endocr Relat Cancer 23 (12) T211-T226, doi:10.1530/ERC-16-0299 first published on 31 August 2016
    ...of CDK and cyclin proteins in premetazoan lineages. BMC Evolutionary Biology 14 1–16. (doi:10.1186/1471-2148- 14-10) Chan SC, Li Y & Dehm SM 2012 Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen...
  7. Review:
    • Rosalinda M Savoy and
    • Paramita M Ghosh
    The dual role of filamin A in cancer: can't live with (too much of) it, can't live without it Endocr Relat Cancer 20 (6) R341-R356, doi:10.1530/ERC-13-0364 first published on 9 October 2013
    ...disassembly and suppressed breast cancer cell migration and invasion (Xu et al. 2010). Similarly, in prostate cancer, FlnA binding promoted androgen receptor (AR) localization to the nucleus (Ozanne et al. 2000), which is thought to promote prostate cancer progression; however, once in the nucleus...
  8. Review:
    • Shyh-Han Tan and
    • Marja T Nevalainen
    Signal transducer and activator of transcription 5A/B in prostate and breast cancers Endocr Relat Cancer 15 (2) 367-390, doi:10.1677/ERC-08-0013
    ...-STAT5A/B and androgen receptor (AR) signaling in prostate cancer cells. Binding of prolactin (PRL) to prolactin receptor (PRLR) results in receptor dimerization and activates the receptor associated kinase, Janus kinase 2 (JAK2). JAK2 phosphorylates the PRLR on tyrosine residues, thereby creating...
  9. Review:
    • Etienne Leygue and
    • Leigh C Murphy
    A bi-faceted role of estrogen receptor β in breast cancer Endocr Relat Cancer 20 (3) R127-R139, doi:10.1530/ERC-12-0389 first published on 26 March 2013
    ...), consistent with a role in epithelial differentiation. More insight into the molecular mechanisms by which this occurs has recently been published using immortalized prostate epithelial and prostate cancer cell line models (Mak et al. 2013). Furthermore, it was also shown that these effects were mediated...
  10. Original Research:
    • A Bardin,
    • N Boulle,
    • G Lazennec,
    • F Vignon,
    • and P Pujol
    Loss of ERβ expression as a common step in estrogen-dependent tumor progression Endocr Relat Cancer 11 (3) 537-551, doi:10.1677/erc.1.00800
    ...replacement therapy and ovarian cancer. Epidemiology 15 100–104. Fujimura T, Takahashi S, Urano T, Ogawa S, Ouchi Y, Kitamura T, Muramatsu M & Inoue S 2001 Differential expression of estrogen receptor b (ERb) and its C-terminal truncated splice variant ERbcx as prognostic predictors in human prostatic cancer...
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