Searching journal content for articles similar to Öberg and Lamberts 23 (12): R551.

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  1. ...of Integrative Biology and Pharmacology, University of Texas, Texas 77225, Houston, USA *(A Saveanu and A Barlier contributed equally to this work) Abstract Gastroenteropancreatic neuroendocrine tumors (GEP–NETs) raise difficult therapeutic problems despite the emergence of targeted therapies. Somatostatin...
  2. ... M, Annibale B, Moretti A, Silecchia G, Scopinaro F, Basso N, Bordi C, et al. 1998 Use of the somatostatin analogue octreotide to localise and manage R434Review G K Dimitriadis et al. Secretory syndromes in GEP-NETs DOI: 10.1530/ERC-16-0200 http://.endocrinology-journals.org © 2016 Society for Endocrinology...
  3. ...but will be generated by an ongoing clinical trial (CLARINET forte, NCT02651987) in progressive GEP-NET. The expression of a truncated splice variant of sstr-5 was associated with poor biochemical response to octreotide in acromegaly (Marina et  al. 2015). The finding that tumor expression of the truncated sstr-5...
  4. ...stimulation, granuleIntroduction The clinical presentation of gastroenteropancreatic neuroendocrine tumours (GEP-NETs) varies according to the site and size of the primary tumour, the presence or absence of metastatic spread, whether associated features compatible with a hereditary syndrome exist or not...
  5. ...as the gold standard in nuclear imaging for patients with GEP-NETs (Krenning et al. 1993). The somatostatin analogue octreotide binds with high affinity to receptor subtypes 2 and 5. Several authors demonstrated that a positive [111In-DTPA0]octreotide scintigraphy is mainly due to the sst2, whereas sst1–sst5...
  6. ...–720neuroendocrine adrenal glands), endocrine islets (within the thyroid or pancreas) as well asREVIEW Somatostatin analogu of neuroendocrine tum and mechanisms Simona Grozinsky-Glasberg1,2, Ilan Sh and Ashley B Grossman1 1Barts and the London School of Medicine, Centre for Endocrinology, Un 2Institute...
  7. ...and nonfunctioning NET (Rinke et al. 2009). More in detail, patients with low-grade (Ki-67!2%) and low hepatic tumor load NET, even if non-functioning, are likely to benefit from octreotide treatment as first-line therapy (Rinke et al. 2009). Different from GEP NET, and due to the limited number of clinical studies...
  8. ...(2011) 18 287–300 Introduction adrenal chromaffin cells and extra-adrenal paraganglia respectively (Eisenhofer et al. 2008). These tumorspancreatic neuroendocrine tumors (GEP-NETs). Quantitative RT-PCR of sst1–3 and sst5, D2, NAT, VMAT1/2 was performed in all tumors, while immunohistochemistry analysis...
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