Searching journal content for predictor (as phrase) in full text.

Displaying results 1-10 of 373
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  1. Thematic Review:
    • Lucas Leite Cunha,
    • Marjory Alana Marcello,
    • Vinicius Rocha-Santos,
    • and Laura Sterian Ward
    Immunotherapy against endocrine malignancies: immune checkpoint inhibitors lead the way Endocr Relat Cancer 24 (12) T261-T281, doi:10.1530/ERC-17-0222 first published on 11 September 2017
    ...of these drugs and their adverse effects indicate that a predictor of clinical response is urgently needed. One attempt at prediction involves the histopathological assessment of the tumor microenvironment, which could hypothetically identify the tumors that would be more or less vulnerable to checkpoint ~~~
  2. Thematic Review:
    • Robert C Mould,
    • Jacob P van Vloten,
    • Amanda W K AuYeung,
    • Khalil Karimi,
    • and Byram W Bridle
    Immune responses in the thyroid cancer microenvironment: making immunotherapy a possible mission Endocr Relat Cancer 24 (12) T311-T329, doi:10.1530/ERC-17-0316 first published on 14 September 2017
    ...). In another study, actively replicating lymphocytes, which were identified based on expression of the proliferation-associated nuclear antigen Ki-67, were identified as a particularly strong predictor of extended disease-free survival in both children and young adults (Gupta et al. 2001). CD8+ T lymphocytes ~~~
  3. Thematic Review:
    • Stephan Gasser,
    • Lina H K Lim,
    • and Florence S G Cheung
    The role of the tumour microenvironment in immunotherapy Endocr Relat Cancer 24 (12) T283-T295, doi:10.1530/ERC-17-0146 first published on 28 July 2017
    ...implications DOI: 10.1530/ERC-17-0146 http://.endocrinology-journals.org 2017 Society for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. 24:12 Recent clinical findings using checkpoint inhibitors suggest that the degree of T cell infiltration in the tumour is an important predictor ~~~
  4. Review:
    • Joanna Grey and
    • Kym Winter
    Patient quality of life and prognosis in MEN2 Endocr Relat Cancer ERC-17-0335, doi:10.1530/ERC-17-0335 first published on 24 October 2017
    ...suffering with 309 chronic conditions, and has been found to be a key predictor of longer survival for both breast 310 cancer patients and HIV sufferers (Turner & Kelly 2000) It would be reasonable to predict that it has 311 similar indications for MEN patients. Clinicians play an integral part ~~~
  5. Review:
    • Vincenzo Marotta,
    • Maria Chiara Zatelli,
    • Concetta Sciammarella,
    • Maria Rosaria Ambrosio,
    • Marta Bondanelli,
    • Annamaria A L Colao,
    • and Antongiulio Faggiano
    Chromogranin A as circulating marker for diagnosis and management of neuroendocrine neoplasms: more flaws than fame Endocr Relat Cancer ERC-17-0269, doi:10.1530/ERC-17-0269 first published on 24 October 2017
    ...-elevated marker levels. By contrast, data about 410 localized disease are still poor. 411 Circulating CgA has long been used as an indirect survival predictor in clinical practice of NEN 412 management. This was due to the well-demonstrated relationship with disease stage/extent, which 413 represents the main ~~~
  6. Research:
    • B Wan,
    • L Dai,
    • L Wang,
    • Y Zhang,
    • H Huang,
    • G Qian,
    • and T Yu
    Knockdown of BRCA2 enhances cisplatin and cisplatin-induced autophagy in ovarian cancer cells Endocr Relat Cancer ERC-17-0261, doi:10.1530/ERC-17-0261 first published on 24 October 2017
    ...Journal of Cancer 127 2790-2803. 432 De Picciotto N, Cacheux W, Roth A, Chappuis PO & Labidi-Galya SI 2016 Ovarian cancer: 433 Status of homologous recombination pathway as a predictor of drug response. Critical 434 Reviews in Oncology/Hematology 101 50-59. 435 Dungl DA, Maginn EN & Stronach EA 2015 ~~~
  7. Research:
    • Takeshi Ujike,
    • Motohide Uemura ,
    • Atsunari Kawashima,
    • Akira Nagahara,
    • Kazutoshi Fujita,
    • Yasushi Miyagawa,
    • and Norio Nonomura
    A novel model to predict positive prostate biopsy based on serum androgen level Endocr Relat Cancer ERC-17-0134, doi:10.1530/ERC-17-0134 first published on 18 October 2017
    ...PSA, PSAD and %FT were independent 48 predictors of cancer detection. We developed a predictive model based on 49 PSAD and %FT, for which the area under the curve was significantly greater 50 Page 3 of 40 than that of PSA (0.82 versus 0.66), a well-known predictor. Applying this 51 analysis ~~~
  8. Review:
    • Iuri Martin Goemann,
    • Mirian Romitti,
    • Erika L Souza Meyer,
    • Simone Magagnin Wajner,
    • and Ana Luiza Maia
    Role of thyroid hormones in the neoplastic process: an overview Endocr Relat Cancer 24 (11) R367-R385, doi:10.1530/ERC-17-0192
    ...predictor of malignancy in thyroid nodules investigated by fineneedle aspiration. Journal of Clinical Endocrinology and Metabolism 91 4295–4301. (doi:10.1210/jc.2006-0527) Boguslawska J, Wojcicka A, Piekielko-Witkowska A, Master A & Nauman A 2011 MiR-224 targets the 3′UTR of type 1 5′-iodothyronine ~~~
  9. Commentary:
    • Giorgio Secreto,
    • Paola Muti,
    • Milena Sant,
    • Elisabetta Meneghini,
    • and Vittorio Krogh
    Medical ovariectomy in menopausal breast cancer patients with high testosterone levels: a further step toward tailored therapy Endocr Relat Cancer 24 (11) C21-C29, doi:10.1530/ERC-17-0251 first published on 16 August 2017
    ...and potentially dangerous (Smith etal. 2014, Sestak & Cuzick 2015). Clinical and pathological parameters are commonly used as predictors of late recurrence. Multigene signatures might also be used to identify women at increased risk of late relapse but, actually, these biomarkers are not routinely adopted ~~~
  10. Research:
    • Gadi Shlomai,
    • Zara Zelenko,
    • Irini Markella Antoniou,
    • Marilyn Stasinopoulos,
    • Aviva Tobin-Hess,
    • Michael P Vitek,
    • Derek LeRoith,
    • and Emily Jane Gallagher
    OP449 inhibits breast cancer growth without adverse metabolic effects Endocr Relat Cancer 24 (10) 519-529, doi:10.1530/ERC-17-0077
    ...AD, Lanasa MC, Friedman DR, Goodman BK, et al. 2011a SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target. Blood 118 41504158. (doi:10.1182/blood-2011-04-351072) Christensen DJ, Ohkubo N, Oddo J ~~~
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