Metabolic profiling of cholesterol and sex steroid hormones to monitor urological diseases

  1. Jayoung Kim2,3
  1. 1Molecular Recognition Research Center, Korea Institute of Science and Technology, Seoul, Korea
  2. 2Departments of Surgery and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA
  3. 3Department of Medicine, University of California, Los Angeles, California, USA
  1. Correspondence should be addressed to M H Choi or J Kim; Email: mh_choi{at}kist.re.kr or Jayoung.Kim{at}cshs.org
  1. Figure 1

    Overview of cholesterol and steroid hormone pathways.

  2. Figure 2

    Our metabolomic profile showing the distinct patterns between prostate cancer and healthy controls.

  3. Figure 3

    High cholesterol, high sex steroids and hair loss were observed in mice with chronic high-cholesterol diet. Line within the value represents the median.

  4. Figure 4

    Metabolic ratios of hair androgens in patients with prostate cancer and male pattern baldness compared with healthy control subjects. Line within the value represents the median.

  5. Figure 5

    The clinically applicable hair metabolomic approaches to monitor cholesterol and steroid hormone levels in urological diseases.

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