Pro-survival and anti-apoptotic properties of androgen receptor signaling by oxidative stress promote treatment resistance in prostate cancer

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   Figure 1

   Schematic representation of the links between the transcription factors that induce AR expression and promote the development of CRPC. Full colour version of this figure available via http://dx.doi.org/10.1530/ERC-12-0232.
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   Figure 2

   Schematic representation of the pro-survival and anti-apoptotic properties of AR signaling that promote therapeutic resistance to androgen deprivation therapy, chemotherapeutic agents (taxanes), and radiation. Full colour version of this figure available via http://dx.doi.org/10.1530/ERC-12-0232.

• © 2012 Society for Endocrinology