2005The let-7 microRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans.
Developmental Cell
9403–
414.
2009Low-level expression of microRNAs let-7d and miR-205 are prognostic markers of head and neck squamous cell carcinoma.
American Journal of Pathology
174736–
745.
2008A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk.
Cancer Research
688535–
8540.
2009MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents.
Molecular Cancer Therapeutics[in press].
2005Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system.
Developmental Dynamics
234868–
877.
2005The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans.
Developmental Cell
8321–
330.
2009CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma – A miRNA microarray analysis.
Genes, Chromosomes & Cancer
48615–
623.
2006Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs.
Cold Spring Harbor Symposia on Quantitative Biology
7121–
27.
2009MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling.
Cancer Research
693278–
3282.
2001Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans.
Genes and Development
152654–
2659.
2008Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.
Molecular Cancer Therapeutics
72152–
2159.
2008Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival, and transformation
from follicular lymphoma.
Journal of Cellular and Molecular Medicine
131248–
1260.
2009let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of
Wee1 kinase in primary fibroblasts.
Journal of Biological Chemistry
2846605–
6609.
2007Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development.
Molecular Biology and Evolution
242525–
2534.
2007Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression
and favorable prognosis.
Cancer Research
6710117–
10122.
2009Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes
and expression of let-7a and IGF-II.
European Journal of Cancer
452212–
2218.
2009Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states
in WI-38 human fibroblasts.
Journal of Cellular Physiology
221109–
119.
2008Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their
sensitization to doxorubicin-induced apoptosis by miR-1.
Journal of Biological Chemistry
28333394–
33405.
2008MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin
lymphomas.
American Journal of Pathology
173242–
252.
2008Regulation of the Drosophila lin-41 homologue dappled by let-7 reveals conservation of a regulatory mechanism within the LIN-41 subclade.
Developmental Dynamics
237196–
208.
2009MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells.
Molecular Pharmacology
751374–
1379.
2008Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.
Journal of Biological Chemistry
28321310–
21314.
2009Overexpression of HMGA2 relates to reduction of the let-7 and its relationship to clinicopathological features in pituitary
adenomas.
Modern Pathology
22431–
441.
2008MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent
growth.
Cell Research
18549–
557.
2002The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster.
Developmental Biology
244170–
179.
2004Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and
human neuronal differentiation.
Genome Biology
5R13.
2009HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapy.
Nucleic Acids Research
374371–
4384.
2004Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival.
Cancer Research
643753–
3756.
2008Regulation of ABCG2 expression at the 3′ untranslated region of its mRNA through modulation of transcript stability and protein
translation by a putative microRNA in the S1 colon cancer cell line.
Molecular and Cellular Biology
285147–
5161.
2009Let-7 microRNA rransfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progression.
Human Gene Therapy
20831–
844.
2009HMGA2 maintains oncogenic RAS-induced epithelial–mesenchymal transition in human pancreatic cancer cells.
American Journal of Pathology
174854–
868.
2009Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen
resistance.
Bioinformatics
25430–
434.
2008MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and
patient poor prognosis.
RNA
142348–
2360.
2008aMicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting
PTEN.
Cancer Research
68425–
433.
2008bMicroRNA microarray identifies let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer.
Cancer Research
6810307–
10314.
2008Role of microRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells.
Biochemical Pharmacology
76582–
588.