Blood dosimetry from a single measurement of the whole body radioiodine retention in patients with differentiated thyroid carcinoma
- Department of Nuclear Medicine, University of Würzburg, Oberdürrbacher Straße 6, D-97080 Würzburg, Germany
1Divisions of Endocrinology and Nuclear Medicine, Departments of Internal Medicine and Radiology, The Ohio State University, 446 McCampbell Hall, 1581 Dodd Drive Columbus, OH 43210-1296, USA
- (Correspondence should be addressed to H Hänscheid; Email: haenscheid{at}nuklearmedizin.uni-wuerzburg.de)
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Figure 1
Blood dose estimates eD (t) from single whole body retention measurements after A, t=6 h; B, t=24 h; C, t=48 h; and D, from the first measurement after at least 3 days versus actual blood dose (aD). Filled dots represent measurements of patients included in the present investigation (n=29), open circles in C are data from Hänscheid et al. (2006), n=59.
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Figure 2
Ratios eD/aD for blood dose estimates (eD) from A, a single whole body retention measurement after t=48 h; and B, from the whole body residence time τtotal body according to Equation 3 versus actual blood dose (aD). Filled dots represent measurements of patients included in the present investigation (n=29), open circles are data from Hänscheid et al. (2006), n=59.
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Figure 3
Activities calculated from 48 h retentions to induce 1.3 Gy blood dose versus actual specific blood dose. Values were set to the calculated activity or 7.4 GBq (200 mCi), whichever was greatest. Filled dots represent measurements of patients included in the present investigation (n=29), open circles are data from Hänscheid et al. (2006), n=59. The curve represents the blood dose limit of 2 Gy.
- © 2009 Society for Endocrinology
