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Research:
- Anita Boelen,
- Anne H van der Spek,
- Flavia Bloise,
- Emmely M de Vries,
- Olga V Surovtseva,
- Mieke van Beeren,
- Mariette T Ackermans,
- Joan Kwakkel,
- and Eric Fliers
Tissue thyroid hormone metabolism is differentially regulated during illness in mice J Endocrinol 233 (1) 25-36, doi: 10.1530/JOE-16-0483 First published online 27 January 2017
....01. Illness-induced alterations in liver thyroid hormone metabolism In the present study, we evaluated the components of local thyroid hormone metabolism such as TH transporters (MCT8 ( Slc16A2 ) and MCT10 ( Slc16A10 )), deiodinases and Thrb1 (the main TR in liver) mRNA expression. Local thyroid hormone...
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Research:
- E M de Vries,
- H C van Beeren,
- M T Ackermans,
- A Kalsbeek,
- E Fliers,
- and A Boelen
Differential effects of fasting vs food restriction on liver thyroid hormone metabolism in male rats J Endocrinol 224 (1) 25-35, doi: 10.1530/JOE-14-0533 First published online 27 October 2014
...191 Lacking thyroid hormone receptor b gene does not influence Research E M DE VRIES and others Fasting and hepatic thyroid hormone metabolism 224 :1 34707–714. (doi:10.1677/.1.07056) Boelen A, Boorsma J, Kwakkel J, Wieland CW, Renckens R, Visser TJ, Fliers E & Wiersinga WM 2008 Type 3 deiodinase...
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Research:
- Patricia C Lisboa,
- Ellen P S Conceição,
- Elaine de Oliveira,
- and Egberto G Moura
Postnatal overnutrition programs the thyroid hormone metabolism and function in adulthood J Endocrinol 226 (3) 219-226, doi: 10.1530/JOE-15-0237 First published online 22 July 2015
...is associated with permanent reprogramming of brown adipose tissue adaptive thermogenesis. Endocrinology 148 4150–4159. (doi:10.1210/ en.2007-0373) Received in final form 19 July 2015 Accepted 21 July 2015 Accepted Preprint published online 22 July 2015thyroid hormone metabolism and bioavailability. Endocrine...
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Review:
- Emmely M de Vries,
- Eric Fliers,
- and Anita Boelen
The molecular basis of the non-thyroidal illness syndrome J Endocrinol 225 (3) R67-R81, doi: 10.1530/JOE-15-0133 First published online 13 May 2015
...Schematic representation of the mechanisms involved in the inflammationinduced inhibition of type 1 deiodinase (D1) expression and activity. (A) Under physiological conditions, thyroid hormone receptor (TR) mediated gene transcription needs the presence of co-factors such as steroid receptor co...
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Research:
- P C Lisboa,
- E de Oliveira,
- A C Manhães,
- A P Santos-Silva,
- C R Pinheiro,
- V Younes-Rapozo,
- L C Faustino,
- T M Ortiga-Carvalho,
- and E G Moura
Effects of maternal nicotine exposure on thyroid hormone metabolism and function in adult rat progeny J Endocrinol 224 (3) 315-325, doi: 10.1530/JOE-14-0473 First published online 4 February 2015
...obesity, dyslipidemia, diabeTRb1 content in liver as well as lower 5 0-D1 activity in muscle; and higher 5 0-D2 activity in brown adipose tissue (BAT), heart, and testis, which are in accordance with hypothyroidism. Although deiodinase activities were not changed in the hypothalamus, pituitary...
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Research:
- Joachim M Weitzel,
- Torsten Viergutz,
- Dirk Albrecht,
- Rupert Bruckmaier,
- Marion Schmicke,
- Armin Tuchscherer,
- Franziska Koch,
- and Björn Kuhla
Hepatic thyroid signaling of heat-stressed late pregnant and early lactating cows J Endocrinol 234 (2) 129-141, doi: 10.1530/JOE-17-0066 First published online 12 May 2017
...partum DIO1 HS-P1 HS-P2 PF-P1 PF-P2 rip t ( l R * * ** PPARGC1A HS-P1 HS-P2 PF-P1 PF-P2 rip t ( l R 0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 Figure 2 mRNA abundances of (A, B) thyroid hormone receptor alpha (THRA), (C, D) deiodinase 1 (DIO1), (E, F) nuclear respiratory factor 1 (NRF1), and (G, H...
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Review:
- Juan Bernal
Thyroid hormone regulated genes in cerebral cortex development J Endocrinol 232 (2) R83-R97, doi: 10.1530/JOE-16-0424 First published online 16 November 2016
...maturation takes place. Then, I will use current concepts on cerebral 232 Correspondence should be addressed to J Bernal Email [email protected] Key Words f brain f development f fetus f gene expression f thyroid hormone metabolism Journal of Endocrinology (2017) 232, R83–R97 Review R84Thyroid hormones...
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Review:
- Flavia F Bloise,
- Aline Cordeiro,
- and Tania Maria Ortiga-Carvalho
Role of thyroid hormone in skeletal muscle physiology J Endocrinol JOE-16-0611, doi: 10.1530/JOE-16-0611 First published online 19 October 2017
...of the iodothyronine selenodeiodinases. Endocr 450 Rev23 38-89. 451 Bloise FF, van der Spek AH, Surovtseva OV, Ortiga-Carvalho TM, Fliers E & Boelen A 2016 452 Differential Effects of Sepsis and Chronic Inflammation on Diaphragm Muscle Fiber Type, 453 Thyroid Hormone Metabolism, and Mitochondrial Function. Thyroid...
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Review:
- Rosalba Senese,
- Federica Cioffi,
- Pieter de Lange,
- Fernando Goglia,
- and Antonia Lanni
Thyroid: biological actions of ‘nonclassical’ thyroid hormones J Endocrinol 221 (2) R1-R12, doi: 10.1530/JOE-13-0573 First published online 24 January 2014
...nan ia Port’Arsa 11, 82100 Benevento, Italy Email Key Words " thyroid hormone " nongenomic effects " thyroid hormone metabolism " thyroid hormone receptors humans, T4 is synthesized entirely within the thyroid and o expressed in the kidney, esent in the CNS, anterior pituitary, brown adipose tissue...
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Review:
- Aurea Orozco,
- Carlos Valverde-R,
- Aurora Olvera,
- and Carlota García-G
Iodothyronine deiodinases: a functional and evolutionary perspective J Endocrinol 215 (2) 207-219, doi: 10.1530/JOE-12-0258 First published online 7 August 2012
...of deiodinase and thyroid hormone receptor expressionwww.endocrinology-journals.orgoestrogen- and androgen-related genes by triiodothyronine in the brain of Silurana tropicalis. Journal of Neuroendocrinology 22 1023–1031. (doi:10.1111/ j.1365-2826.2010.02047.x) Eales JG 1997 Iodine metabolism and thyroid...

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