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Research:
- Chao Li,
- Bin Yang,
- Zhihao Xu,
- Eric Boivin,
- Mazzen Black,
- Wenlong Huang,
- Baoyou Xu,
- Ping Wu,
- Bo Zhang,
- Xian Li,
- Kunsong Chen,
- Yulian Wu,
- and Gina R Rayat
Protective effect of cyanidin-3-O-glucoside on neonatal porcine islets J Endocrinol 235 (3) 237-249, doi: 10.1530/JOE-17-0141 First published online 20 September 2017
...phosphorylation of ERK1/2 and PI3K/AKT at a concentration of greater than or equal to 0.5 μM, and the phosphorylation of ERK1/2 and PI3K/AKT reached maximum at 6–12 h (Fig. 4B and E). In addition, we investigated the effect of C3G on NRF2 nuclear translocation and the subsequent HO1 induction. After ~~~
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Review:
- Flavia F Bloise,
- Aline Cordeiro,
- and Tania Maria Ortiga-Carvalho
Role of thyroid hormone in skeletal muscle physiology J Endocrinol JOE-16-0611, doi: 10.1530/JOE-16-0611 First published online 19 October 2017
...phosphorylation 230 in male rats due to the increased activity of cytochrome c oxidase 1 and 4 (COX1 and COX4, 231 respectively), the last enzymes in the electron transport chain of mitochondria (Bahi et al. 2005). 232 Additionally, healthy young men treated with T3 for 14 days demonstrated an incre ~~~
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Research:
- Eirini Meimaridou,
- Michelle Goldsworthy,
- Vasileios Chortis,
- Ersi Fragouli,
- Paul A Foster,
- Wiebke Arlt,
- Roger Cox,
- and Louise A Metherell
NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice J Endocrinol JOE-16-0638, doi: 10.1530/JOE-16-0638 First published online 18 October 2017
...phosphorylation and A-tailing, adapter ligation and PCR amplification was performed 214 to prepare the library for sequencing. Paired-end sequencing was performed over 100 cycles 215 on the Illumina HiSeq2000 platform using TruSeq v3 chemistry. Fastq files were generated 216 from the sequencing plat ~~~
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Research:
- Jin-Bong Lee,
- Sung-Jin Yoon,
- Sang-Hyun Lee,
- Moo-Seung Lee,
- Haiyoung Jung,
- Tae-Don Kim,
- Suk Ran Yoon,
- Inpyo Choi,
- Ik-Soo Kim,
- Su Wol Chung,
- Hee Gu Lee,
- Jeong-Ki Min,
- and Young-Jun Park
Ginsenoside Rg3 ameliorated HFD-induced hepatic steatosis through downregulation of STAT5-PPARγ J Endocrinol 235 (3) 223-235, doi: 10.1530/JOE-17-0233
...phosphorylation of PPARγ is a crucial factor in modulating adipose tissue function, specifically as it relates to diabetes and obesity (Hosooka et al. 2008, Choi et al. 2010, Li et al. 2011, Banks et al. 2015). The Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling ~~~
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Research:
- Tsutomu Wada,
- Akari Ishikawa,
- Eri Watanabe,
- Yuto Nakamura,
- Yusuke Aruga,
- Hayate Hasegawa,
- Yasuhiro Onogi,
- Hiroe Honda,
- Yoshinori Nagai,
- Kiyoshi Takatsu,
- Yoko Ishii,
- Masakiyo Sasahara,
- Daisuke Koya,
- Hiroshi Tsuneki,
- and Toshiyasu Sasaoka
Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance J Endocrinol 235 (3) 179-191, doi: 10.1530/JOE-17-0351 First published online 30 August 2017
...phosphorylation levels of NFkB were significantly increased in the eWAT and liver of HFD mice, whereas they were maintained at normal levels in the HFD + Ep mice (Fig. 5C). In addition, the eplerenone treatment caused decrease (or tended to decrease) in the expression of the proinflammatory genes i ~~~
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Review:
- Rhonda D Prisby
Mechanical, hormonal and metabolic influences on blood vessels, blood flow and bone J Endocrinol 235 (3) R77-R100, doi: 10.1530/JOE-16-0666 First published online 16 August 2017
...phosphorylation ~~~
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Review:
- Alejandro Ibáñez-Costa and
- Márta Korbonits
AIP and the somatostatin system in pituitary tumours J Endocrinol 235 (3) R101-R116, doi: 10.1530/JOE-17-0254 First published online 23 August 2017
...phosphorylation ~~~
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Research:
- Laura E Pascal,
- Khalid Z Masoodi,
- June Liu,
- Xiaonan Qiu,
- Qiong Song,
- Yujuan Wang,
- Yachen Zang,
- Tiejun Yang,
- Yao Wang,
- Lora H Rigatti,
- Uma Chandran,
- Leandro M Colli,
- Ricardo Z N Vencio,
- Yi Lu,
- Jian Zhang,
- and Zhou Wang
Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia J Endocrinol 235 (2) 123-136, doi: 10.1530/JOE-17-0112
...phosphorylation by androgen-induced tumor suppressor U19/EAF2 in the mouse prostate. Cancer Microenvironment 6 247–261. (doi:10.1007/s12307-013-0132-4) Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, et al. 2011 Human mediato ~~~
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Research:
- Svetlana I Sofronova,
- Dina K Gaynullina,
- Anastasia A Shvetsova,
- Anna A Borzykh,
- Ekaterina K Selivanova,
- Daria S Kostyunina,
- Anna P Sharova,
- Andrey A Martyanov,
- and Olga S Tarasova
Antenatal/early postnatal hypothyroidism alters arterial tone regulation in 2-week-old rats J Endocrinol 235 (2) 137-151, doi: 10.1530/JOE-17-0225 First published online 9 August 2017
...phosphorylation of its regulatory subunit (MYPT1) at different sites. The effects of such phosphorylation are opposite: while activation of NO pathway results in the increase of MLCP activity, Rho-kinase inhibits MLCP. Thus, antenatal/ early postnatal hypothyroidism can increase the level of myosin ~~~
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Review:
- Juliano C da Silveira,
- Ana Clara F.c.m. de Avila,
- Hannah L Garrett,
- Jason Bruemmer,
- Quinton Winger,
- and Gerrit Bouma
Cell-secreted vesicles containing microRNAs as regulators of gamete maturation J Endocrinol JOE-17-0200, doi: 10.1530/JOE-17-0200 First published online 4 September 2017
...phosphorylation and block in cell proliferation (Zhang et al. 2013). Finally, we identified 338 changes in EV microRNAs and potential targets belonging to the TGFβ signaling 339 member family (IL6, COL1A2, ID2, STAT1 and CDC25A) in follicle growth and 340 development in young and old mares (da Silve ~~~

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