...hypothalamus (Pereira et al. 2015) or skeletal muscle (Spangenburg et al. 2006, Trenerry et al. 2007, Begue et al. 2013). Since whole-body
SOCS3-knockout mice exhibit embryonic lethality (Roberts et al. 2001), we employed the Cre-loxP system to produce tissue-specific
SOCS3 ablation, as previously d ~~~