Searching journal content for deiodinases (as phrase) in full text.

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  1. ...deiodinases (D2) or by the inactivation of T4 27 into reverse T3 by deiodinases type 3 (D3). SM relaxation and contraction rates depend on T3 28 regulation of myosin expression and energy supplied by substrate oxidation in the mitochondria. 29 The balance between D2 and D3 expression determines TH i ~~~
  2. ...deiodinases and the control of intracellular thyroid hormone signaling during cellular differentiation. Biochimica et Biophysica Acta 1830 3937–3945. (doi:10.1016/j.bbagen.2012.05.007) Duntas LH & Brenta G 2012 The effect of thyroid disorders on lipid levels and metabolism. Medical Clinics of North ~~~
  3. ...deiodinases (D1–3) importantly regulate the bioavailability of T3 in targets cells, while TH is also metabolized by glucuronidation and sulfation, which enhance biliary excretion (Engler & Burger 1984, Burger 1986, Visser 1996). Other modifications of iodothyronines include decarboxylation of the al ~~~
  4. ...deiodinases in central and peripheral tissues determine tissue­specific TH levels and TH primarily exerts their actions through interaction with TRs, and finally affecting TH­dependent physiological activities. Our laboratory has found that different propensities to obesity might be related to HPT a ~~~
  5. ...deiodinases (Piehl et al. 2011, Gereben et al. 2015). The combined action of THR together with its ligand regulates a wide variety of TH target genes via TH response elements. The primary THR targets include other transcription factors (e.g. the nuclear respiratory factor-1, NRF1) and transcriptiona ~~~
  6. ...deiodinases in human liver. Journal of Clinical Endocrinology and Metabolism 83 2868–2874. (doi:10.1210/ jc.83.8.2868) Ruas JL, Poellinger L & Pereira T 2002 Functional analysis of hypoxiainducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcript ~~~
  7. ...deiodinases ~~~
  8. ...deiodinases present in the tissue rather than by serum TH concentrations alone. T3 binds to thyroid hormone receptors which mediate gene transcription. Two thyroid hormone receptor genes have been described, Thra and Thrb . Through alternative splicing and alternative promoter usage many isoforms ar ~~~
  9. ...deiodinases f thyroid hormone receptors Journal of Endocrinology (2017) 232 R67–R81 Review R68Thyroid hormones and innate immune cells DOI: 10.1530/JOE-16-0462 a h van der spek and others http://.endocrinology-journals.org © 2017 Society for Endocrinology Printed in Great Britain Published by Biosci ~~~
  10. ...deiodinases (DIO1 and DIO2). T4 and T3 are inactivated by 5­deiodination catalyzed by type 3 deiodinase (DIO3) with the formation of 3,3′5′­triiodothyronine (reverse T3, or rT3) and 3,3′­diiodothyronine (T2), respectively (Bianco et al. 2002, Bianco 2011). The human brain has no DIO1 activity (Campo ~~~
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