...clock genes f glucocorticoids f ghrelin f leptin f melatonin f orexin Journal of Endocrinology (2017) 232, R141–R159 Review R142Fish endocrine and circadian systems DOI: 10.1530/JOE-16-0330 e isorna and others http://.endocrinology-journals.org © 2017 Society for Endocrinology Printed in Great Brita ~~~

...clock genes ~~~

...clock genes may contain additional regulatory elements (e.g., CRE) through which their expression is regulated by cellular and environmental signals. Collectively, the circadian molecular clock operates in nearly every cell of the body to regulate at least half the genome (Zhang et al. 2014). In SCN ~~~

...clock genes inhibit their own transcription (Hardin & Panda 2013). In mammals, photoperiodicity is likely regulated by the circadian clock located in the SCN, because lesions of the SCN disrupt photoperiodic responses (Rusak & Morin 1976). In mammals and birds, the core oscillator of the circadian c ~~~

...clock genes in rat cumulus-oocyte complex: changes after pinealectomy. Journal of Pineal Research 58 490–499. (doi:10.1111/jpi.12234) Cordoba J, Steindl P & Blei AT 2009 Melatonin arrhythmia is corrected after liver transplantation. American Journal of Gastroenterology 104 1862–1863. (doi:10.1038/aj ~~~

...clock genes are also expressed in numerous peripheral tissues (Boden et al. 2010). We have recently shown that the expression of core clock genes in the SCN changes significantly across gestation in the mouse (Wharfe et  al. 2016), and Wharfe and coworkers have also previously demonstrated that cloc ~~~

...clock genes " glucocorticoids " pregnancy addell 1995). This HPA axis se it promotes the release of h fetal demand (Atkinson & Research M D WHARFE and others Circadian clock and HPA axis in pregnancy 228 :3 135–147hypothalamic–pituitary–adrenal (HPA) axis after mid-these maternal adaptations, enhanc ~~~

...clock genes in the suprachiasmatic nucleus and the pars tuberalis of the sheep: evidence for an internal coincidence timer. PNAS 99 13890–13895. (doi:10.1073/pnas.212517599) Lincoln GA, Andersson H & Hazlerigg D 2003 Clock genes and the longterm regulation of prolactin secretion: evidence for a phot ~~~