The image depicts cultured differentiated podocytes incubated with adipocyte-conditioned medium and an IgG isotype antibody. Desmin is stained green, cell nuclei are stained blue. This study demonstrates that adipocyte-derived factors can impair renal function, and that adipocyte-derived factors play an important role in obesity-related podocytopathy. From Chen et al. 2016 231 109&3x2013;120. Credit: J-Y Chen, D-Y Jian, C-C Lien, Y-T Lin, C-H Ting, L-K Chen, T-C Hsu, H-M Huang, Y-T Wu, T-T Kuan, Y-W Chao, L-Y Wu, S-W Huang & C-C Juan (National Yang-Ming University, Taipei, Taiwan)