The images depict: (l) a portrait of Geoffrey Wingfield Harris; (r) double immunofluorescence against beta-catenin (green) and growth hormone (red), magnification 400X. Credit: (l) GeoffreyWingfield Harris, courtesy Bassano Ltd, National Portrait Gallery, UK NPG X172149. Copyright National Portrait Gallery, London; (r) reproduced, with permission, from Gaston-Massuet C, Andoniadou CL, Signore M, Jayakody SA, Charolidi N, Kyeyune R,Vernay B, Jacques TS, Taketo MM, Le Tissier P, et al. (2011) Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans. PNAS 108 11482–11487.