Decorin induced by progesterone plays a crucial role in suppressing endometriosis

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  • Supplementary Figure 1 - (A) We evaluated the expression of ER mRNA and PR mRNA, in the primary cultured cells (HMOsis scl2 and HMOsis scl3) which were stromal cells derived from ovarian endometrioma and CRL-7566 endometriosis cell line using RT-PCR. HMOsis scl2, HMOsis scl3 and CRL-7566 cells were identified as ER and PR positive as with EMOsis cc/TERT cells and CRL-4003 cells. (B) We examined that the mRNA expression of decorin of HMOsis scl2, HMOsis scl3 and CRL-7566 cells with or without dienogest treatment. The HMOsis scl2, HMOsis scl3 and CRL-7566 cells treated with dienogest showed significantly higher expression of decorin mRNA. (PDF 63 KB)

This Article

  1. J Endocrinol November 1, 2014 vol. 223 no. 2 203-216
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