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Figure 2

Neural pathways in circadian control of glucocorticoid release. See text for details. Arrows: black arrows: neural projections targeting the HPA axis. Blue arrows: neural projections via the autonomic nervous system. Purple arrow: projection from the DMH to the ‘autonomic PVN’ distinct from the SCN–adrenal gland pathway. Also the subPVZ projects into this region. Open arrows: humoral transport through the vasculature. Clocks symbolise autonomous pacemakers. Abbreviations: Regions of the nervous system: SCN, suprachiasmatic nucleus; subPVZ, subparaventricular zone; DMH, dorsomedial hypothalamus; PVN, paraventricular nucleus; mpPVN, medioparvocellular division of the PVN; I, interneuron of the PVN; C, corticotrope cell of the pituitary; IML, intermediolateral column of the spinal cord. Hormones and neurotransmitters: AVP, arginine vasopressine; CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone.

This Article

  1. J Endocrinol vol. 200 no. 1 3-22