Searching journal content for articles similar to Gray et al. 58 (1): R1.

Displaying results 1-10 of 803

For checked items

view abstracts
download to citation manager

Select this article
Research:
- Ji Seon Park,
- Su Jung Bae,
- Sik-Won Choi,
- You Hwa Son,
- Sung Bum Park,
- Sang Dal Rhee,
- Hee Youn Kim,
- Won Hoon Jung,
- Seung Kyu Kang,
- Jin Hee Ahn,
- Seong Hwan Kim,
- and Ki Young Kim
A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation J Mol Endocrinol 52 (2) 191-202, doi: 10.1530/JME-13-0177 first published on 20 January 2014
...enhanced BMP2-induced osteoblastogenesis in C2C12 cells and inhibited RANKL-induced osteoclastogenesis in mouse bone marrow-derived macrophages. KR-67500, a new selective 11β-HSD1 inhibitor, may provide a new therapeutic window in the prevention and/or treatment of type 2 diabetes, obesity, and...
Select this article
Research:
- Leping Zhao,
- Yong Pan,
- Kesong Peng,
- Zhe Wang,
- Jieli Li,
- Dan Li,
- Chao Tong,
- Yi Wang,
- and Guang Liang
Inhibition of 11β-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice J Mol Endocrinol 55 (2) 119-131, doi: 10.1530/JME-14-0268 first published on 28 July 2015
...:2 121*a, Rat leydig cells; b, Rat testis microsome; c, CHO-hs-HSD11B1 cells. D E 0.10 5.78 0.18 8.97 0.28 2.30 1Curcumin LG13A O O OCH3 OHHO H3CO CF3 Curcumin LG IC50 (μM) against 11β-HSD1 reductase IC50 (μM) agsupplemented with 10% heat-inactivated FBS in humidified 37 8C and 5% CO2 condition...
Select this article
Research:
- Hanze Du,
- Limei Liu,
- Ying Wang,
- Yuichi Nakagawa,
- Alexei Lyzlov,
- Kabirullah Lutfy,
- Theodore C Friedman,
- Xiaozhong Peng,
- and Yanjun Liu
Specific reduction of G6PT may contribute to downregulation of hepatic 11β-HSD1 in diabetic mice J Mol Endocrinol 50 (2) 167-178, doi: 10.1530/JME-12-0223 first published on 24 December 2012
[email protected] ) Abstract Pre-receptor activation of glucocorticoids via 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1 (HSD11B1)) has been identified as an important mediator of the metabolic syndrome. Hexose-6-phosphate dehydrogenase (H6PDH) mediates 11β-HSD1 amplifying tissue glucocorticoid production by driving...
Select this article
Research:
- Juan Liu,
- Xiaocen Kong,
- Long Wang,
- Hanmei Qi,
- Wenjuan Di,
- Xiao Zhang,
- Lin Wu,
- Xia Chen,
- Jing Yu,
- Juanmin Zha,
- Shan Lv,
- Aisen Zhang,
- Peng Cheng,
- Miao Hu,
- Yujie Li,
- Jianhua Bi,
- Yan Li,
- Fang Hu,
- Yi Zhong,
- Yong Xu,
- and Guoxian Ding
Essential roles of 11β-HSD1 in regulating brown adipocyte function J Mol Endocrinol 50 (1) 103-113, doi: 10.1530/JME-12-0099 first published on 29 November 2012
...significantly upregulated in 11b-HSD1-depleted brown adipocyte 1.2A 0.8 0.4 sio (fo ld 11β-HSD1 Research J LIU, X KONG, L WANG and others 11b-HSD1 and brown adipocyte 50 :1 106function Previously, we have found that expression of BAT-specific genes was significantly decreased in dexamethasone-Bioscience) per...
Select this article
Research:
- Hui Wang,
- Wenjing Wu,
- Jun Duan,
- Ming Ma,
- Wei Kong,
- Yuannan Ke,
- Gang Li,
- and Jingang Zheng
Cardioprotection of ischemic preconditioning in rats involves upregulating adiponectin J Mol Endocrinol 58 (4) 155-165, doi: 10.1530/JME-16-0163 first published on 20 February 2017
...with cardiac knockdowns of APN and its receptors via intramyocardial small-interfering RNA injection were subjected to IPC and then myocardial infarction (MI) at 24 h after IPC. Globular APN (gAd) was injected at 10 min before MI. APN mRNA and protein levels in myocardium as well as the plasma APN...
Select this article
Review:
- Gregory S Y Ong and
- Morag J Young
Mineralocorticoid regulation of cell function: the role of rapid signalling and gene transcription pathways J Mol Endocrinol 58 (1) R33-R57, doi: 10.1530/JME-15-0318 first published on 7 November 2016
..., glucocorticoids can activate the MR (Rossier et al. 2008, Mihailidou et al. 2009). Therefore, the benefits of spironolactone or eplerenone in heart failure are not solely from aldosterone antagonism, but general blockade of MR (Pitt et al. 1999, 2003, Zannad et al. 2011). Hence, the availability of ligand...
Select this article
Research:
- Ying Ying,
- Huazhang Zhu,
- Zhen Liang,
- Xiaosong Ma,
- and Shiwei Li
GLP1 protects cardiomyocytes from palmitate-induced apoptosis via Akt/GSK3b/b-catenin pathway J Mol Endocrinol 55 (3) 245-262, doi: 10.1530/JME-15-0155 first published on 18 September 2015
...-catenin to the nucleus to transactivate the expression of specific genes involved in cell survival and proliferation (Behrens et al. 1996, Miller et al. 1999). Recent studies have suggested that the PI3K/GSK3B/b-catenin signalling pathway shows potential anti-apoptotic effects after myocardial infarction (MI) in rat...
OPEN ACCESS ARTICLE
Select this article
Research:
- Kristine M Wadosky,
- Jessica M Berthiaume,
- Wei Tang,
- Makhosi Zungu,
- Michael A Portman,
- A Martin Gerdes,
- and Monte S Willis
MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo J Mol Endocrinol 56 (3) 273-290, doi: 10.1530/JME-15-0283 first published on 9 February 2016
...with severe heart failure (HF) (Gerdes & Iervasi 2010, Iervasi & Nicolini 2013). Treatment with TH following myocardial infarction is cardioprotective (Mourouzis et al. 2011, Pantos et al. 2007a) and promotes elements of physiological hypertrophic response after cardiac injury (Mourouzis et al. 2013a). T3...
Select this article
Research:
- Su M Hlaing,
- Leah A Garcia,
- Jaime R Contreras,
- Keith C Norris,
- Monica G Ferrini,
- and Jorge N Artaza
1,25-Vitamin D₃ promotes cardiac differentiation through modulation of the WNT signaling pathway J Mol Endocrinol 53 (3) 303-317, doi: 10.1530/JME-14-0168 first published on 19 August 2014
...of myocardial infarction, even after controlling for factors associated with coronary artery disease. A growing body of evidence indicates that vitamin D plays an important role in CVD-related signaling pathways. However, little is known about the molecular mechanism by which vitamin D modulates heart...
Select this article
Regular papers:
- Yanjun Liu,
- Yuichi Nakagawa,
- Ying Wang,
- Limei Liu,
- Hongwei Du,
- Wei Wang,
- Xiuhai Ren,
- Kabirullah Lutfy,
- and Theodore C Friedman
Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice J Mol Endocrinol 41 (2) 53-64, doi: 10.1677/JME-08-0004 first published on 4 June 2008
...dehydrogenase (H6PDH)-generating NADPH system. Pharmacological inhibition of 11β-HSD1 improves insulin intolerance and obesity. Here, we evaluated the potential beneficial effects of 11β-HSD1 inhibitor carbenoxolone (CBX) in diet-induced obese (DIO) and insulin-resistant mice by examining the possible influence...

For checked items

view abstracts
download to citation manager

Journal of Molecular Endocrinology

Searching journal content for articles similar to Gray et al. 58 (1): R1.

Search Results

Modify Results

This search

New Articles: issue in progress

Most

Viewed

Cited

Citation format:
Results / page:
Results order: