Searching journal content for articles similar to Wall et al. 57 (1): R49.

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  1. Review:
    • Tram B Doan,
    • J Dinny Graham,
    • and Christine L Clarke
    Emerging functional roles of nuclear receptors in breast cancer J Mol Endocrinol 58 (3) R169-R190, doi: 10.1530/JME-16-0082 first published on 13 January 2017
    ...DOI: 10.1530/JME-16-0082 http://.endocrinology-journals.org © 2017 Society for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. 10.1530/JME-16-0082 Nuclear receptors in breast cancer t b doan and others Review R169–R1903 58: Tram B Doan, J Dinny Graham and Christine L...
  2. Thematic Review:
    • Weiwei Fan,
    • Annette R Atkins,
    • Ruth T Yu,
    • Michael Downes,
    • and Ronald M Evans
    Road to exercise mimetics: targeting nuclear receptors in skeletal muscle J Mol Endocrinol 51 (3) T87-T100, doi: 10.1530/JME-13-0258
    ...in the human body and is the major site for energy expenditure. It exhibits remarkable plasticity in response to physiological stimuli such as Key Words " exerciseRoad to exercise mimetic nuclear receptors in skel Weiwei Fan1, Annette R Atkins1,2, Ruth T Yu1, Michael Do 1Gene Expression Laboratory 2Howard...
  3. Review:
    • Xianjie Wen and
    • Yisheng Yang
    Emerging roles of GLIS3 in neonatal diabetes, type 1 and type 2 diabetes J Mol Endocrinol 58 (2) R73-R85, doi: 10.1530/JME-16-0232 first published on 29 November 2016
    ...in GLIS3 cause a neonatal diabetes syndrome, characterized by neonatal diabetes, congenital hypothyroidism and polycystic kidney. Importantly, genome-wide association studies showed that variations of GLIS3 are strongly associated with both type 1 diabetes (T1D) and type 2 diabetes (T2D) in multiple...
  4. Research:
    • Haoyong Yu,
    • Mingliang Zhang,
    • Yunqin Ma,
    • Junxi Lu,
    • Jiemin Pan,
    • Pan Pan,
    • Haibing Chen,
    • and Weiping Jia
    5-ALA ameliorates hepatic steatosis through AMPK signaling pathway J Mol Endocrinol 59 (2) 121-128, doi: 10.1530/JME-16-0260 first published on 31 May 2017
    ...), likely through the restoration of phosphorylation levels of AMPK (Thr172) and acetyl-CoA (ACC) (Ser79), further enhanced PGC1α and CPT1α expression. Introduction NAFLD is the most common liver disease worldwide. It comprises a spectrum of disorders characterized by liver steatosis, with >5...
  5. Erratum:
    • Weiwei Fan,
    • Annette R Atkins,
    • Ruth T Yu,
    • Michael Downes,
    • and Ronald M Evans
    Road to exercise mimetics: targeting nuclear receptors in skeletal muscle J Mol Endocrinol 52 (1) X1, doi: 10.1530/JME-13-0258e
    ...; Zierath JR 2012 Acute exercise remodels promoter methylation in human skeletal muscle. Cell Metabolism 15 405–411. ( doi:10.1016/j.cmet.2012.01.001 ). jme;52/1/X1 10.1530/JME-13-0258e 0952-5041 1479-6813 Road to exercise mimetics: targeting nuclear receptors in skeletal muscle Road to exercise mimetics...
  6. Review:
    • Rebecca H Ritchie,
    • Eser J Zerenturk,
    • Darnel Prakoso,
    • and Anna C Calkin
    Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy J Mol Endocrinol 58 (4) R225-R240, doi: 10.1530/JME-16-0249 first published on 3 April 2017
    ..., overexpression of Ppar-alpha in a cardiac-specific manner mimics much of the changes observed in the setting of diabetes including increased FA oxidation and decreased glucose oxidation, with concomitant cardiac hypertrophy and dysfunction (Finck et al. 2002). In settings of both T1D and T2D, the heart becomes...
  7. Review:
    • Kyle T Helzer,
    • Christopher Hooper,
    • Shigeki Miyamoto,
    • and Elaine T Alarid
    Ubiquitylation of nuclear receptors: new linkages and therapeutic implications J Mol Endocrinol 54 (3) R151-R167, doi: 10.1530/JME-14-0308 first published on 5 May 2015
    ...of nuclear receptor signaling Nuclear receptors (NRs) comprise a family of transcriptional regulators that control multiple physiological estradiol (E2) (Toft & Gorski 1966, Jensen et al. 1967). X receptor (RXR, NR2B1–3), vitamin D receptor (VDR, NR1I1), peroxisomeproliferato tivation domain, a central DNA...
  8. Thematic Review:
    • Shannon E Mullican,
    • Joanna R DiSpirito,
    • and Mitchell A Lazar
    The orphan nuclear receptors at their 25-year reunion J Mol Endocrinol 51 (3) T115-T140, doi: 10.1530/JME-13-0212 first published on 4 October 2013
    ...varies (Benoit et al. 2004, Markov & Laudet 2011). Nevertheless, once an identified, the corresponding dopted’ (Benoit et al. 2006). igand regulation, orphan NRs Thematic Review S E MULLICAN, J R DISPIRITO and M A LAZAR 25 years of orphan nuclear receptors 51 :3 T115–T140(DBD) consists of two zinc finger...
  9. Review:
    • Marcel J M Schaaf
    Nuclear receptor research in zebrafish J Mol Endocrinol 59 (1) R65-R76, doi: 10.1530/JME-17-0031 first published on 24 April 2017
    ...Society for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. R72Review m j m schaaf Zebrafish nuclear receptors 59 1: PPAR ligands like fibrates and thiazolidinediones have proven to be effective therapies against metabolic disorders like diabetes. They have been shown to decrease...
  10. Review:
    • Zodwa Dlamini,
    • Fortunate Mokoena,
    • and Rodney Hull
    Abnormalities in alternative splicing in diabetes: therapeutic targets J Mol Endocrinol 59 (2) R93-R107, doi: 10.1530/JME-17-0049
    ...& Engagements Portfolio, Mangosuthu University of Technology, Durban, South Africa Abstract Diabetes mellitus (DM) is a non-communicable, metabolic disorder that affects 416 million individuals worldwide. Type 2 diabetes contributes to a vast 85–90% of the diabetes incidences while 10–15% of patients suffer...
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