Searching journal content for articles similar to Kleinau et al. 57 (1): R59.

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  1. Review:
    • Bice Chini and
    • Marco Parenti
    G-protein-coupled receptors, cholesterol and palmitoylation: facts about fats J Mol Endocrinol 42 (5) 371-379, doi: 10.1677/JME-08-0114 first published on 8 January 2009
    ..., Italy (Correspondence should be addressed to B Chini; Email: [email protected]) Abstract G-protein-coupled receptors (GPCRs) are integral membrane prot structural and functional features are modulated by both proteins a on the assembly and signalling of GPCRs has been extensively i impetus has been...
  2. Review:
    • Emily Tubbs and
    • Jennifer Rieusset
    Metabolic signaling functions of ER–mitochondria contact sites: role in metabolic diseases J Mol Endocrinol 58 (2) R87-R106, doi: 10.1530/JME-16-0189 first published on 13 December 2016
    ...DOI: 10.1530/JME-16-0189 http://.endocrinology-journals.org © 2017 Society for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. 10.1530/JME-16-0189 MAM, a hub of hormone and nutrient signaling e tubbs and j rieusset Review R87–R1062 58: Emily Tubbs1 and Jennifer Rieusset2 1...
  3. Review:
    • Daniel Raleigh,
    • Xiaoxue Zhang,
    • Benoît Hastoy,
    • and Anne Clark
    The β-cell assassin: IAPP cytotoxicity J Mol Endocrinol 59 (3) R121-R140, doi: 10.1530/JME-17-0105 first published on 15 August 2017
    ...). The term ‘oligomer’ describes assemblies of small numbers of β-strands/molecules (dimers-multimers) at the beginning of the process of amyloidogenesis (Glabe 2006). The protein molecules are non-covalently linked in the polymeric (fibril) state by backbone hydrogen bonding and side...
  4. Review:
    • Davide Calebiro,
    • Viacheslav O Nikolaev,
    • and Martin J Lohse
    Imaging of persistent cAMP signaling by internalized G protein-coupled receptors J Mol Endocrinol 45 (1) 1-8, doi: 10.1677/JME-10-0014 first published on 8 April 2010
    ...: [email protected] Abstract G protein-coupled receptors (GPCRs) are the largest family of plas several endogenous cues and serve as important pharmacologica in GPCR signaling have been characterized in great detail, little is cells. The recent advent of optical methods based on fluorescent r...
  5. Articles:
    • LM Luttrell
    'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors J Mol Endocrinol 30 (2) 117-126, doi: 10.1677/jme.0.0300117
    ...G PROTEIN-COUPLED RECEPTOR SIGNALLING IN NEUROENDOCRINE SYSTEMS ‘Location, location, location’: activation and targeting of MAP kinases by G protein-coupled receptors L M Luttrell Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA and The Geriatrics Research...
  6. Review:
    • Russell A Prough,
    • Barbara J Clark,
    • and Carolyn M Klinge
    Novel mechanisms for DHEA action J Mol Endocrinol 56 (3) R139-R155, doi: 10.1530/JME-16-0013 first published on 23 February 2016
    ..., it is now clear that DHEA and DHEA-S act directly as ligands for many hepatic nuclear receptors and G-protein-coupled receptors. In addition, it can function to mediate acute cell signaling pathways. This review summarizes the molecular mechanisms by which DHEA acts in cells and animal models with a focus...
  7. Articles:
    • B Chini and
    • M Parenti
    G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there? J Mol Endocrinol 32 (2) 325-338, doi: 10.1677/jme.0.0320325
    ..., Conner & Schmid 2003, Nabi & Le 2003) and, finally, the fine-tuning of components of the cell signalling machinery located on the cell surface (Simons & Ikonen 1997, Okamoto et al. 1998, Simons & Toomre 2000). A number of receptor tyrosine kinases (RTKs), G-protein coupled receptors (GPCRs), G...
  8. Research:
    • Juliane Dinter,
    • Jessica Mühlhaus,
    • Simon Friedrich Jacobi,
    • Carolin Leonie Wienchol,
    • Maxi Cöster,
    • Jaroslawna Meister,
    • Carolin Stephanie Hoefig,
    • Anne Müller,
    • Josef Köhrle,
    • Annette Grüters,
    • Heiko Krude,
    • Jens Mittag,
    • Torsten Schöneberg,
    • Gunnar Kleinau,
    • and Heike Biebermann
    3-iodothyronamine differentially modulates α-2A-adrenergic receptor-mediated signaling J Mol Endocrinol 54 (3) 205-216, doi: 10.1530/JME-15-0003 first published on 15 April 2015
    ..., 205–216 Research J DINTER, J MU¨HLHAUS and others 3-T1AM-modulated signaling at ADRA2A 54 :3 205–216reduced by co-stimulation with 3-T1AM. The present study therefore points to a complex spectrum of signaling modification mediated by 3-T1AM at different G protein-coupled receptors.We tested two...
  9. Research:
    • Jana Fischer,
    • Gunnar Kleinau,
    • Anne Müller,
    • Peter Kühnen,
    • Denise Zwanziger,
    • Anita Kinne,
    • Maren Rehders,
    • Lars C Moeller,
    • Dagmar Führer,
    • Annette Grüters,
    • Heiko Krude,
    • Klaudia Brix,
    • and Heike Biebermann
    Modulation of monocarboxylate transporter 8 oligomerization by specific pathogenic mutations J Mol Endocrinol 54 (1) 39-50, doi: 10.1530/JME-14-0272
    ...studies of G-protein-coupled receptors (GPCRs) that an equilibrium may exist between monomers and oligomers (Lambert 2010, Teichmann et al. 2012, Calebiro et al. 2013), implying that protomer–protomer interfaces are flexible or transient. Amino acid mutations can shift this equilibrium toward a monomeric...
  10. Research:
    • Ting-Ting Zhou,
    • Fei Ma,
    • Xiao-Fan Shi,
    • Xin Xu,
    • Te Du,
    • Xiao-Dan Guo,
    • Gai-Hong Wang,
    • Liang Yu,
    • Vatcharin Rukachaisirikul,
    • Li-Hong Hu,
    • Jing Chen,
    • and Xu Shen
    DMT efficiently inhibits hepatic gluconeogenesis by regulating the Gαq signaling pathway J Mol Endocrinol 59 (2) 151-169, doi: 10.1530/JME-17-0121 first published on 21 June 2017
    ...AMP) response element-binding protein (CREB)-regulated transcriptional coactivator 2 (CRTC2) phosphorylation and cytoplasmic translocation (Dentin  et  al. 2007). Glucagon binds to glucagon receptor (GCGR), a G protein-coupled receptor (GPCR), and activates Gαs/ cAMP/protein kinase A (PKA)/CREB/CRTC2 signaling...
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