Searching journal content for articles similar to Giandomenico et al. 51 (3): 277.

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  1. ...REVIEW Multiple intracellular eVectors modulate physiological functions of the cloned somatostatin receptors T Florio and G Schettini Institute of Pharmacology, School of Medicine, University of Genoa, Unit of Neuroscience, Advanced Biotechnology Center (CBA), National Institute for Cancer Research...
  2. ...) and somatostatin receptor 5 (SSTR5) are receptors found in the brain. DRD2 is expressed in lactotrophs and inhibits prolactin release. SSTR5 is involved in the regulation of GH and TSH. Both DRD2 and SSTR5 are also involved in ACTH release in pituitary tumors (Tani et al. 2011). Calcium-dependent secretion...
  3. ...of the five subtypes of G-protein-coupled somatostatin receptors (SSTR), SSTR1– identification of key SST teristics provided the ratio design of novel analogs that cognate receptors. Somatostatin receptor lSSTR2 (dopastatin), are briefly discussed.tory activity and an antiproliferative role. Furthermore...
  4. ...somatostatin receptor expression was the development of radioactive ligands for diagnostic purposes such as 111In-DTPA-[D-Phe1] octreotide (Octreoscan; Reubi 2003, Weckbecker et al. 2003). A rapid uptake of 111In-radiolabeled somatostatin analogs by tumor cells allows the in vivo localization of tumors...
  5. ...pituitary gland function, mainly inhibiting hormone secretion and to some extent pituitary tumor cell growth. SRIF-14 via its cognate G-protein-coupled receptors (subtypes 1–5) activates multiple cellular signaling pathways including adenylate cyclase/cAMP, MAPK, Key Words " somatostatin " receptors...
  6. ...forms (usually 111In-pentetreotide), these analogs are also useful for somatostatin receptor imaging (SRI) (Kaltsas et al. 2001, Chrisoulidou et al. 2007); however, they bind with high affinity to only sst2 DOI: 10.1677/JME-08-0012arising from the adrenal medulla or extra-adrenal neural crest. PHEO...
  7. ...receptor (IGFR; Hagemeister & Sheridan 2008, Hanson et al. 2010). CTGGACAAAATGGACAA-3 0 (forward primer) and 0 0 A L HAGEMEISTER and others . Somatostatin receptor signaling318The objective of this study was to establish receptor– effector pathway linkages for fish SSTRs. To this end, Chinese hamster...
  8. ...inwardly Table 1 Nomenclature of human somatostatin and urotensin II receptors Receptorsa Genesb Somatostatin receptors SST1 SSTR1 SST2 SSTR2 SST3 SSTR3 SST4 SSTR4 SST5 SSTR5 Urotensin receptor UT UTS2R aReceptor nomenclature follows the International Union of Basic and Clinical Pharmacology (IUPHAR...
  9. ...factors for Ras-proximate 1 and 2 (Rap1 and 2). GHRHR, growth hormone-releasing hormone receptor; CRHR, corticotrophin-releasing hormone receptor; DRD2, dopamine receptor D2; SST, somatostatin receptor; PDE, phosphodiesterase; AC, adenylyl cyclase. Published by Bioscientifica Ltd. 20q13 and contains 13...
  10. .... Somatostatin and dopamine in the pituitary362Figure 1 (A) Principal intracellular signalling cascades asso (or somatostatin analogues) binding to somatostatin receptors i channels. Phosphotyrosine phosphatases and mitogen-activate phosphotyrosine phosphatase, may also produce cytostatic actio well. Most...
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