Searching journal content for ubiquitination (as phrase) in full text.

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  1. Review:
    • Daniel Raleigh,
    • Xiaoxue Zhang,
    • Benoît Hastoy,
    • and Anne Clark
    The β-cell assassin: IAPP cytotoxicity J Mol Endocrinol 59 (3) R121-R140, doi: 10.1530/JME-17-0105 first published on 15 August 2017
    ...ubiquitination for degradation via the proteasome. proIAPP is packaged in the Golgi, together with insulin and processing enzymes, into secretory granules. Maturation and post-translational processing of the peptide occurs in the granule where prohIAPP/ hIAPP is largely stabilised by interaction wit ~~~
  2. Research:
    • Long The Nguyen,
    • Sonia Saad,
    • Yi Tan,
    • Carol Pollock,
    • and Hui Chen
    Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus J Mol Endocrinol 59 (1) 81-92, doi: 10.1530/JME-17-0056 first published on 12 May 2017
    ...ubiquitination ~~~
  3. Research:
    • Katarzyna Zielniok,
    • Agnieszka Sobolewska,
    • and Małgorzata Gajewska
    Mechanisms of autophagy induction by sex steroids in bovine mammary epithelial cells J Mol Endocrinol 59 (1) 29-48, doi: 10.1530/JME-16-0247 first published on 20 April 2017
    ...ubiquitination system and is involved in the conjugation of cleaved LC3 with phosphatidylethanolamine (PE); LC3-I protein undergoes C-terminal cleavage and conjugation with PE, DOI: 10.1530/JME-16-0247 http://.endocrinology-journals.org © 2017 Society for Endocrinology Printed in Great Britain Publi ~~~
  4. Review:
    • Fabio Luiz Fernandes-Rosa,
    • Sheerazed Boulkroun,
    • and Maria-Christina Zennaro
    Somatic and inherited mutations in primary aldosteronism J Mol Endocrinol 59 (1) R47-R63, doi: 10.1530/JME-17-0035 first published on 11 April 2017
    ...ubiquitination and degradation Figure 4 Aldosterone biosynthesis in APA in presence of mutations affecting intracellular calcium balance. Mutations in ATP2B3 coding for PMCA3, CACNA1D, encoding the α subunit of the L-type Ca2+ channel Cav1.3, and CACNA1H, encoding the α subunit of the T-type Ca2+ ch ~~~
  5. Research:
    • Tingyuan Ren,
    • Yuping Zhu,
    • Xuejuan Xia,
    • Yongbo Ding,
    • Jing Guo,
    • and Jianquan Kan
    Zanthoxylum alkylamides ameliorate protein metabolism disorder in STZ-induced diabetic rats J Mol Endocrinol 58 (3) 113-125, doi: 10.1530/JME-16-0218 first published on 18 January 2017
    ...ubiquitination . Hereditas 35 17 – 26 . ( doi:10.3724/SP.J.1005.2013.00017 ) Meena KR & Kanwar SS 2015 Lipopeptides as the antifungal and antibacterial agents: applications in food safety and therapeutics . BioMed Research International 2015 1 – 9 . ( doi:10.1155/2015/473050 ) Michaelides A , Ra ~~~
    OPEN ACCESS ARTICLE
  6. Review:
    • Emily Tubbs and
    • Jennifer Rieusset
    Metabolic signaling functions of ER–mitochondria contact sites: role in metabolic diseases J Mol Endocrinol 58 (2) R87-R106, doi: 10.1530/JME-16-0189 first published on 13 December 2016
    ...ubiquitination (Sugiura et al. 2013). However, this widely accepted concept was recently challenged as both increased ER–mitochondria interactions and increased Ca2+ transfer were observed in Mfn2 knockout (KO) cells (Cosson  et  al. 2012, Filadi  et  al. 2015). The discrepancy between studies was s ~~~
  7. Review:
    • Ana Pestana,
    • João Vinagre,
    • Manuel Sobrinho-Simões,
    • and Paula Soares
    TERT biology and function in cancer: beyond immortalisation J Mol Endocrinol 58 (2) R129-R146, doi: 10.1530/JME-16-0195 first published on 5 January 2017
    ...ubiquitination and proteosomal degradation, independent of its telomeric role, suggesting a feedforward mechanism able to potentiate c-MYC-dependent oncogenesis (Koh et al. 2015). NF-κB is one of the most mentioned pathways altered in cancer that controls TERT transcriptional program. In 2000, the e ~~~
  8. Review:
    • T Traboulsi,
    • M El Ezzy,
    • J L Gleason,
    • and S Mader
    Antiestrogens: structure-activity relationships and use in breast cancer treatment J Mol Endocrinol 58 (1) R15-R31, doi: 10.1530/JME-16-0024 first published on 11 October 2016
    ...ubiquitination DOI: 10.1530/JME-16-0024 http://.endocrinology-journals.org © 2017 The authors Printed in Great Britain Published by Bioscientifica Ltd. R16Review t traboulsi, m el ezzy and others Mechanisms of antiestrogenicity 58 1: observed in tumors that have progressed under treatment with tamox ~~~
    OPEN ACCESS ARTICLE
  9. Review:
    • Carrie S Shemanko
    Prolactin receptor in breast cancer: marker for metastatic risk J Mol Endocrinol 57 (4) R153-R165, doi: 10.1530/JME-16-0150 first published on 22 September 2016
    ...ubiquitination by SCFβTrCP (Plotnikov et  al. 2008, Varghese et  al. 2008). Control over the PRLR protein levels can therefore vary from mRNA levels under different cellular circumstances. Additionally, the natural regulation of PRL induction of PRLR degradation appears to be impaired in breast canc ~~~
  10. Review:
    • Suzy Markossian and
    • Frédéric Flamant
    CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists J Mol Endocrinol 57 (2) R81-R92, doi: 10.1530/JME-15-0305 first published on 7 June 2016
    ...ubiquitination and proteasomal degradation of DNA ligase IV, also inhibit NHEJ and increase HDR/NHEJ ratio (Chu et al. 2015). An ingenious alternative strategy is to destabilize Cas9 during the G1 and S phases of the cell cycle, by fusing it to a domain of Geminin, as HDR mainly takes place during t ~~~
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