Searching journal content for nuclear receptors (as phrase) in full text.

Displaying results 1-10 of 307
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  1. Research:
    • Kamran Ullah,
    • Tanzil Ur Rahman,
    • Hai-Tao Pan,
    • Meng-Xi Guo,
    • Xin-Yan Dong,
    • Juan Liu,
    • Lu-Yang Jin,
    • Yi Cheng,
    • Zhang-Hong Ke,
    • Jun Ren,
    • Xian-Hua Lin,
    • Xiao-Xiao Qiu,
    • Ting-Ting Wang,
    • He-Feng Huang,
    • and Jian-Zhong Sheng
    Serum estradiol levels in controlled ovarian stimulation directly affect the endometrium J Mol Endocrinol 59 (2) 105-119, doi: 10.1530/JME-17-0036 first published on 24 May 2017
    ...nuclear receptors for oxysterols liver X receptor induces ovarian hyperstimulation syndrome in mice. Endocrinology 150 3369–3375. (doi:10.1210/en.2008-1519) Ng EHY, Yeung WSB, Lau EYL, So WWK & Ho PC 2000 High serum oestradiol concentrations in fresh IVF cycles do not impair implantation and pregnan ~~~
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  2. Review:
    • Marcel J M Schaaf
    Nuclear receptor research in zebrafish J Mol Endocrinol 59 (1) R65-R76, doi: 10.1530/JME-17-0031 first published on 24 April 2017
    ...nuclear receptors 59 1: and subsequent mutation, the capacity to bind different ligands and the ligand-independent activation were acquired. Phylogenetic analysis has led to the classification of the NR superfamily into seven subfamilies (NR0–6) on which the current nomenclature of the NR superfamil ~~~
  3. Review:
    • Rebecca H Ritchie,
    • Eser J Zerenturk,
    • Darnel Prakoso,
    • and Anna C Calkin
    Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy J Mol Endocrinol 58 (4) R225-R240, doi: 10.1530/JME-16-0249 first published on 3 April 2017
    ...nuclear receptors ~~~
  4. Review:
    • Tram B Doan,
    • J Dinny Graham,
    • and Christine L Clarke
    Emerging functional roles of nuclear receptors in breast cancer J Mol Endocrinol 58 (3) R169-R190, doi: 10.1530/JME-16-0082 first published on 13 January 2017
    ...nuclear receptors other than the estrogen and progesterone receptors, in the regulation of various processes important to the initiation and progression of breast cancer. We review new insights into the mechanisms of action of NRs made possible by recent advances in genomic technologies and focus on ~~~
  5. Review:
    • Jaya Nautiyal
    Transcriptional coregulator RIP140: an essential regulator of physiology J Mol Endocrinol 58 (3) R147-R158, doi: 10.1530/JME-16-0156 first published on 10 January 2017
    ...nuclear receptors provide a docking platform for coregulators to bind, these proteins bring enzymatic capabilities to the gene regulatory sites. RIP140 is a transcriptional coregulator essential for several physiological processes, and aberrations in its function may lead to diseased states. Unlike ~~~
  6. Research:
    • Alessandra Mingione,
    • Chiara Verdelli,
    • Stefano Ferrero,
    • Valentina Vaira,
    • Vito Guarnieri,
    • Alfredo Scillitani,
    • Leonardo Vicentini,
    • Gianni Balza,
    • Edoardo Beretta,
    • Annalisa Terranegra,
    • Giuseppe Vezzoli,
    • Laura Soldati,
    • and Sabrina Corbetta
    Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors J Mol Endocrinol 58 (2) 91-103, doi: 10.1530/JME-16-0184 first published on 21 November 2016
    ...nuclear receptors (Savoy & Ghosh 2013). In human parathyroid tumor cells, full-length FLNA was localized in membrane and in cytoplasm, similar to what was reported in bovine parathyroid cells (Hjälm et al. 2001); in addition, cleaved FLNA fragment could be detected in the nuclear protein fractions, ~~~
  7. Review:
    • T Traboulsi,
    • M El Ezzy,
    • J L Gleason,
    • and S Mader
    Antiestrogens: structure-activity relationships and use in breast cancer treatment J Mol Endocrinol 58 (1) R15-R31, doi: 10.1530/JME-16-0024 first published on 11 October 2016
    ...nuclear receptors (NRs) a common structure with a central DNA-binding domain (DBD) flanked by two transcriptional activation function domains, AF1 and AF2, the latter overlapping with the ligand-binding domain (LBD) (Fig.  2A). Ligand binding regulates NR conformation, nuclear localization, binding ~~~
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  8. Review:
    • Gregory S Y Ong and
    • Morag J Young
    Mineralocorticoid regulation of cell function: the role of rapid signalling and gene transcription pathways J Mol Endocrinol 58 (1) R33-R57, doi: 10.1530/JME-15-0318 first published on 7 November 2016
    ...nuclear receptors contain an amino terminal domain (NTD), DNAbinding domain (DBD), hinge region and a ligandbinding domain (LBD). The MR and other steroid hormone receptors are activated through ligand–LBD interaction, but other parts of their structure can affect outcomes. The NTD, via its activati ~~~
  9. Research:
    • Kent Wehmeier,
    • Luisa M Onstead-Haas,
    • Norman C W Wong,
    • Arshag D Mooradian,
    • and Michael J Haas
    Pro-inflammatory signaling by 24,25-dihydroxyvitamin D3 in HepG2 cells J Mol Endocrinol 57 (2) 87-96, doi: 10.1530/JME-16-0009 first published on 27 May 2016
    ...nuclear receptors that regulate lipid and cholesterol metabolism. Therefore, we investigated the effect of 24,25-[OH]2D3 on kinase signaling, nuclear receptor expression, and proinflammatory cytokine expression in HepG2 cells. Materials and methods Materials Phorbol-12-myristate-13-acetate (PMA), ge ~~~
  10. Review:
    • Silvia Giatti,
    • Roberto Cosimo Melcangi,
    • and Marzia Pesaresi
    The other side of progestins: effects in the brain J Mol Endocrinol 57 (2) R109-R126, doi: 10.1530/JME-16-0061 first published on 23 June 2016
    ...nuclear receptors . Pharmacological Reviews 58 685 – 704 . ( doi:10.1124/pr.58.4.2 ) ↵ Ghoumari AM , Baulieu EE & Schumacher M 2005 Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures . Neuroscience 135 47 – 58 . ( doi:10.1016/j.neuroscience.2005.05.023 ) ~~~
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