Searching journal content for ion channels (as phrase) in full text.

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  1. Review:
    • Daniel Raleigh,
    • Xiaoxue Zhang,
    • Benoît Hastoy,
    • and Anne Clark
    The β-cell assassin: IAPP cytotoxicity J Mol Endocrinol 59 (3) R121-R140, doi: 10.1530/JME-17-0105 first published on 15 August 2017
    ...ion channels and proteins interacting with extracellular matrix. Intragranular IAPP will come into close proximity with all of these components on exocytosis of the secretory granule. It has been shown that interaction of monomeric human IAPP with synthetic phospholipid membranes or bilayers promote ~~~
  2. Review:
    • Fabio Luiz Fernandes-Rosa,
    • Sheerazed Boulkroun,
    • and Maria-Christina Zennaro
    Somatic and inherited mutations in primary aldosteronism J Mol Endocrinol 59 (1) R47-R63, doi: 10.1530/JME-17-0035 first published on 11 April 2017
    ...ion channels (KCNJ5 (Choi et al. 2011), CACNA1D (Azizan et al. 2013, Scholl et al. 2013) and CACNA1H (Daniil et al. 2016)) and ATPases (ATP1A1 (Azizan et al. 2013, Beuschlein et al. 2013) and ATP2B3 (Beuschlein et al. 2013)) in more than 50% of APA. All these mutations lead to the activation of calc ~~~
  3. Research:
    • Anthony L Albiston,
    • Mauricio Cacador,
    • Puspha Sinnayah,
    • Peta Burns,
    • and Siew Yeen Chai
    Insulin-regulated aminopeptidase inhibitors do not alter glucose handling in normal and diabetic rats J Mol Endocrinol 58 (4) 193-198, doi: 10.1530/JME-17-0033 first published on 29 March 2017
    ...ion channels ~~~
  4. Review:
    • Murat Bastepe,
    • Serap Turan,
    • and Qing He
    Heterotrimeric G proteins in the control of parathyroid hormone actions J Mol Endocrinol 58 (4) R203-R224, doi: 10.1530/JME-16-0221
    ...ion channels and src tyrosine kinase, which in turn generate various intracellular second messengers. The Gβγ complex also regulates a range of effector proteins, some of which are Figure 1 A summary diagram of G protein-mediated pathways activated by PTH. R205Review 58 4: DOI: 10.1530/JME-16-0221 h ~~~
  5. Review:
    • Emily Tubbs and
    • Jennifer Rieusset
    Metabolic signaling functions of ER–mitochondria contact sites: role in metabolic diseases J Mol Endocrinol 58 (2) R87-R106, doi: 10.1530/JME-16-0189 first published on 13 December 2016
    ...ion channels between secretory pathway compartments (Kottgen  et  al. 2005). PACS2 was identified at ER–mitochondria interface where it plays a role in sorting proteins on the ER and mitochondria (Simmen  et  al. 2005). PACS2 depletion disrupts mitochondria structure and ER homeostasis, Mitochondria ~~~
  6. Review:
    • Gregory S Y Ong and
    • Morag J Young
    Mineralocorticoid regulation of cell function: the role of rapid signalling and gene transcription pathways J Mol Endocrinol 58 (1) R33-R57, doi: 10.1530/JME-15-0318 first published on 7 November 2016
    ...ion channels or signalling systems is unaffected by MR deletion in VSMC (Tarjus  et  al. 2015a). However, MR does regulate Cav1.2 gene expression in mesenteric artery VSMC, an L-type calcium channel which increases vasomotor tone when active (McCurley et al. 2012). Aldosterone can also act in an MR- ~~~
  7. Focused Review:
    • Jessica Sabourin and
    • Florent Allagnat
    Store-operated Ca2+ entry: a key component of the insulin secretion machinery J Mol Endocrinol 57 (3) F35-F39, doi: 10.1530/JME-16-0106 first published on 2 September 2016
    ...ion channels formed by other members of the TRP channels family is also addressed. Introduction Insulin secretion is driven by electrical activity and oscillations of intracellular Ca2+ concentration ([Ca2+]i) in pancreatic β-cells. The main driver of insulin secretion is plasma glucose; glucose met ~~~
  8. Research:
    • Sushi Jiang,
    • Hening Zhai,
    • Danjie Li,
    • Jiana Huang,
    • Heng Zhang,
    • Ziru Li,
    • Weizhen Zhang,
    • and Geyang Xu
    AMPK-dependent regulation of GLP1 expression in L-like cells J Mol Endocrinol 57 (3) 151-160, doi: 10.1530/JME-16-0099 first published on 4 August 2016
    ...ion channels and secretion of insulin (da Silva Xavier et  al. 2000, 2003). Previous studies have showed that AICAR, an AMPK activator, increases GLP1 secretion in rodents but not in fetal rat intestinal cells, murine GLUTag or human NCI-H716 L cells (Maida et al. 2011, Mulherin et al. 2011). Our fi ~~~
  9. Research:
    • Kent Wehmeier,
    • Luisa M Onstead-Haas,
    • Norman C W Wong,
    • Arshag D Mooradian,
    • and Michael J Haas
    Pro-inflammatory signaling by 24,25-dihydroxyvitamin D3 in HepG2 cells J Mol Endocrinol 57 (2) 87-96, doi: 10.1530/JME-16-0009 first published on 27 May 2016
    ...ion channels and activation of various mitogen-activated protein (MAP) kinases and pp60c-src (Chappel et  al. 1997, Gniadecki 1998, Zhang et al. 2007, Buitrago et al. 2013). Unlike 1,25-[OH]2D3, which has high affinity for the VDR (Makin et  al. 1989), 24,25-[OH]2D3 binds the VDR poorly if at all (U ~~~
  10. Review:
    • Haihua Yang and
    • Linghai Yang
    Targeting cAMP/PKA pathway for glycemic control and type 2 diabetes therapy J Mol Endocrinol 57 (2) R93-R108, doi: 10.1530/JME-15-0316 first published on 18 May 2016
    ...ion channels ~~~
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