Searching journal content for endometrial cancer (as phrase) in full text.

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  1. Review:
    • Tram B Doan,
    • J Dinny Graham,
    • and Christine L Clarke
    Emerging functional roles of nuclear receptors in breast cancer J Mol Endocrinol 58 (3) R169-R190, doi: 10.1530/JME-16-0082 first published on 13 January 2017
    ...endometrial cancer in women. Cancer Letters 281 1–7. (doi:10.1016/j.canlet.2008.11.002) Wang F, Yeung KL, Chan WC, Kwok CC, Leung SL, Wu C, Chan EY, Yu IT, Yang XR & Tse LA 2013 A meta-analysis on dose-response relationship between night shift work and the risk of breast cancer. Annals of Oncology 2 ~~~
  2. Review:
    • Jaya Nautiyal
    Transcriptional coregulator RIP140: an essential regulator of physiology J Mol Endocrinol 58 (3) R147-R158, doi: 10.1530/JME-16-0156 first published on 10 January 2017
    ...endometrial cancer (EC) progression have recently identified several mutations in RIP140, suggesting its role in impaired ER signalling (Ferreira  et  al. 2014, Gibson  et  al. 2016). Microsatellite instability (MSI), which is a phenotype caused by mutations in the DNA mismatch repair (MMR) genes, i ~~~
  3. Review:
    • T Traboulsi,
    • M El Ezzy,
    • J L Gleason,
    • and S Mader
    Antiestrogens: structure-activity relationships and use in breast cancer treatment J Mol Endocrinol 58 (1) R15-R31, doi: 10.1530/JME-16-0024 first published on 11 October 2016
    ...endometrial cancer in the clinic (Martin & Middleton 1978, Davies et  al. 1979). Increases in mouse uterine wet weight induced by tamoxifen were dependent on the expression of ERα in the uterus (Korach 1994). In addition, although tamoxifen treatment has proven effective in reducing the risk of brea ~~~
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  4. Review:
    • Hong Zhao,
    • Ling Zhou,
    • Anna Junjie Shangguan,
    • and Serdar E Bulun
    Aromatase expression and regulation in breast and endometrial cancer J Mol Endocrinol 57 (1) R19-R33, doi: 10.1530/JME-15-0310 first published on 11 April 2016
    ...endometrial cancer Correspondence should be addressed to H Zhao Email [email protected] Introduction Aromatase is the rate-limiting enzyme in estrogen biosynthesis (Simpson & Santen 2015). The biologically active estrogen, 17β-estradiol (E2), exerts its actions by binding to its receptors, est ~~~
  5. Review:
    • Russell A Prough,
    • Barbara J Clark,
    • and Carolyn M Klinge
    Novel mechanisms for DHEA action J Mol Endocrinol 56 (3) R139-R155, doi: 10.1530/JME-16-0013 first published on 23 February 2016
    ...endometrial cancer cells, DHEA (1 nM–1 µM) activated the ERE-driven luciferase activity in an ER-dependent manner, ascertained by inhibition by cotreatment with the antiestrogen 4-hydroxytamoxifen (Maggiolini et al. 1999). However, in these studies, the authors did not rule out the metabolism of DHE ~~~
  6. Thematic Review:
    • Evan Simpson and
    • Richard J Santen
    Celebrating 75 years of oestradiol J Mol Endocrinol 55 (3) T1-T20, doi: 10.1530/JME-15-0128 first published on 5 October 2015
    ...endometrial cancer in postmenopausal women taking unopposed oestrogen. Another risk 3.0 1.5 ri 0.5 0.0 1st 2nd 3rd Quintile 4th 5th EPIC Key 2.0 1.0 2.5 P<0.001 P<0.0001 Figure 9 The levels of oestradiol are correlatedwith the relative risk of breast cancer.increased by BRCA1 mutations and contribut ~~~
  7. Research:
    • M Rodríguez-Sanz,
    • N García-Giralt,
    • D Prieto-Alhambra,
    • S Servitja,
    • S Balcells,
    • R Pecorelli,
    • A Díez-Pérez,
    • D Grinberg,
    • I Tusquets,
    • and X Nogués
    CYP11A1 expression in bone is associated with aromatase inhibitor-related bone loss J Mol Endocrinol 55 (1) 69-79, doi: 10.1530/JME-15-0079 first published on 24 June 2015
    ...endometrial cancer risk. Gynecologic Oncology 117 255–259. (doi:10.1016/j.ygyno.2010.02.002) Tuckey RC, Li W, Zjawiony JK, Zmijewski MA, Nguyen MN, Sweatman T, Miller D & Slominski A 2008 Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc. FEBS Journal 275 2585–2596. (doi:1 ~~~
  8. Review:
    • Kyle T Helzer,
    • Christopher Hooper,
    • Shigeki Miyamoto,
    • and Elaine T Alarid
    Ubiquitylation of nuclear receptors: new linkages and therapeutic implications J Mol Endocrinol 54 (3) R151-R167, doi: 10.1530/JME-14-0308 first published on 5 May 2015
    ...endometrial cancer . PLoS ONE 7 e46072 . ( doi:10.1371/journal.pone.0046072 ). ↵ Husnjak K &amp; Dikic I 2012 Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions . Annual Review of Biochemistry 81 291 – 322 . ( doi:10.1146/annurev-biochem-051810-094654 ). Hwang C-S , Shemor ~~~
  9. Research:
    • Changgui Shi,
    • Ping Huang,
    • Hui Kang,
    • Bo Hu,
    • Jin Qi,
    • Min Jiang,
    • Hanbing Zhou,
    • Lei Guo,
    • and Lianfu Deng
    Glucocorticoid inhibits cell proliferation in differentiating osteoblasts by microRNA-199a targeting of WNT signaling J Mol Endocrinol 54 (3) 325-337, doi: 10.1530/JME-14-0314 first published on 15 April 2015
    ...endometrial cancer cell proliferation by targeting mammalian target of rapamycin (mTOR). International Journal of Gynecological Cancer 23 1191–1197. (doi:10.1097/IGC.0b013e31829ea779) Xing W, Hao L, Yang X, Li F & Huo H 2014 Glucocorticoids induce apoptosis by inhibiting microRNA cluster miR-17-92 e ~~~
  10. Research:
    • Yue Wang,
    • Xiu Long Niu,
    • Xiao Qin Guo,
    • Jing Yang,
    • Ling Li,
    • Ye Qu,
    • Cun Xiu Hu,
    • Li Qun Mao,
    • and Dan Wang
    IL6 induces TAM resistance via kinase-specific phosphorylation of ERα in OVCA cells J Mol Endocrinol 54 (3) 351-361, doi: 10.1530/JME-15-0011 first published on 5 May 2015
    ...endometrial cancer cells. Interleukin 6 (IL6), a known mediator of immunological and inflammatory events, was elevated in serum and peritoneal fluid of patients with OVCA; high levels of IL6 in body fluids were associated with poor prognosis and survival (Penson et al. 2000, Lane et al. 2011). Resul ~~~
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