Searching journal content for diabetes (as phrase) in full text.

Displaying results 1-10 of 692
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  1. Review:
    • Zodwa Dlamini,
    • Fortunate Mokoena,
    • and Rodney Hull
    Abnormalities in alternative splicing in diabetes: therapeutic targets J Mol Endocrinol 59 (2) R93-R107, doi: 10.1530/JME-17-0049
    ...diabetes contributes to a vast 85–90% of the diabetes incidences while 10–15% of patients suffer from type 1 diabetes. These two predominant forms of DM cause a significant loss of functional pancreatic β-cell mass causing different degrees of insulin deficiency, most likely, due to increased β-cell ~~~
  2. Research:
    • Haoyong Yu,
    • Mingliang Zhang,
    • Yunqin Ma,
    • Junxi Lu,
    • Jiemin Pan,
    • Pan Pan,
    • Haibing Chen,
    • and Weiping Jia
    5-ALA ameliorates hepatic steatosis through AMPK signaling pathway J Mol Endocrinol 59 (2) 121-128, doi: 10.1530/JME-16-0260 first published on 31 May 2017
    ...diabetes mellitus (T2DM), obesity, hypertension, hyperlipidemia, etc. Growing Journal of Molecular Endocrinology (2017) 59, 121–128 Correspondence should be addressed to H Chen or W Jia Email [email protected] or [email protected] Key Words f 5-aminolevulinic acid f nonalcoholic fatty liver diseas ~~~
  3. Research:
    • Susan M van den Berg,
    • Andrea D van Dam,
    • Pascal J Kusters,
    • Linda Beckers,
    • Myrthe den Toom,
    • Saskia van der Velden,
    • Jan Van den Bossche,
    • Irma van Die,
    • Mariëtte R. Boon,
    • Patrick C. N. Rensen,
    • Esther Lutgens,
    • and Menno P de Winther
    Helminth antigens counteract a rapid high-fat diet induced decrease in adipose tissue eosinophils J Mol Endocrinol JME-17-0112, doi: 10.1530/JME-17-0112 first published on 10 July 2017
    ...diabetes ~~~
  4. Research:
    • Seung Chul Kim,
    • Jae-Eon Lee,
    • Seong Soo Kang,
    • Hoe-Saeng Yang,
    • Sun Suk Kim,
    • and Beum-Soo An
    The regulation of oxytocin and oxytocin receptor in human placenta according to gestational age J Mol Endocrinol JME-16-0223, doi: 10.1530/JME-16-0223 first published on 10 July 2017
    ...diabetes ~~~
  5. Research:
    • Yajie Guo,
    • Junjie Yu,
    • Chunxia Wang,
    • Kai Li,
    • Bin Liu,
    • Ying Du,
    • Fei Xiao,
    • Shanghai Chen,
    • and Feifan Guo
    miR-212-5p suppresses lipid accumulation by targeting FAS and SCD1 J Mol Endocrinol JME-16-0179, doi: 10.1530/JME-16-0179 first published on 30 June 2017
    ...diabetes in Lepr(db/db) mice. J Biol Chem 282 15717-15729. 560 Shukla U, Tumma N, Gratsch T, Dombkowski A & Novak RF 2013 Insights into insulin-mediated 561 regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, 562 Akt (protein kinase B), mammalian target ~~~
  6. Research:
    • Chunheng Mo,
    • Long Huang,
    • Lin Cui,
    • Can Lv,
    • Dongliang Lin,
    • Liang Song,
    • Guoqiang Zhu,
    • Juan Li,
    • and Yajun Wang
    Characterization of NMB, GRP and their receptors (BRS3, NMBR and GRPR) in chickens J Mol Endocrinol 59 (1) 61-79, doi: 10.1530/JME-17-0020 first published on 12 May 2017
    ...diabetes in humans (Guan et al. 2010, Majumdar & Weber 2012, Gonzalez et al. 2015). However, unlike NMBR/GRPR, human or mouse BRS3 cannot be effectively activated by GRP/NMB (EC50 >>1000 nM), or by any other naturally occurring bombesin-related peptides (Mantey et al. 1997, Ryan et al. 1998). Hence, ~~~
  7. Research:
    • Long The Nguyen,
    • Sonia Saad,
    • Yi Tan,
    • Carol Pollock,
    • and Hui Chen
    Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus J Mol Endocrinol 59 (1) 81-92, doi: 10.1530/JME-17-0056 first published on 12 May 2017
    ...diabetes mellitus (Guh et al. 2009). Multiple factors can contribute to the development of obesity, among which is the transgenerational effects of maternal obesity. It has been shown in animal models and humans that offspring born to obese mothers tend to have higher risk of obesity and related com ~~~
  8. Research:
    • L J Moran,
    • P A Mundra,
    • H J Teede,
    • and P J Meikle
    The association of the lipidomic profile with features of polycystic ovary syndrome J Mol Endocrinol 59 (1) 93-104, doi: 10.1530/JME-17-0023 first published on 12 May 2017
    ...diabetes (T2D) and cardiovascular disease (CVD) including hyperlipidaemia, hypertension, inflammation, oxidative stress, procoagulation, impaired fibrinolysis and early vascular markers of atherosclerosis including endothelial dysfunction, arterial stiffness, increased carotid intima media wall thic ~~~
  9. Research:
    • Ting-ting Zhou,
    • Fei Ma,
    • Xiao-fan Shi,
    • Xin Xu,
    • Te Du,
    • Xiao-dan Guo,
    • Gai-hong Wang,
    • Liang Yu,
    • Vatcharin Rukachaisirikul,
    • Li-hong Hu,
    • Jing Chen,
    • and Xu Shen
    DMT efficiently inhibits hepatic gluconeogenesis involving Gαq signaling pathway J Mol Endocrinol JME-17-0121, doi: 10.1530/JME-17-0121 first published on 21 June 2017
    ...diabetes 27 mellitus (T2DM) 28 Word count: 5513 29 30 Page 2 of 59 3 Abstract 31 Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with complicated 32 pathogenesis, and targeting gluconeogenesis inhibition is a promising strategy for 33 anti-diabetic drug discovery. G protein-coupled re ~~~
  10. Review:
    • Marcel J M Schaaf
    Nuclear receptor research in zebrafish J Mol Endocrinol 59 (1) R65-R76, doi: 10.1530/JME-17-0031 first published on 24 April 2017
    ...diabetes and obesity (Berger & Moller 2002, Feige et al. 2006). In vertebrates, three PPARs have been identified which are encoded by three different genes: PPARα, PPARβ (also called PPARδ) and PPARγ. They regulate gene expression by binding to PPAR response elements (PPREs) as a heterodimer with RX ~~~
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