Searching journal content for 11β-HSD1 (as phrase) in full text.

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  1. Review:
    • Gillian A Gray,
    • Christopher I White,
    • Raphael F P Castellan,
    • Sara J McSweeney,
    • and Karen E Chapman
    Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium J Mol Endocrinol 58 (1) R1-R13, doi: 10.1530/JME-16-0128 first published on 23 August 2016
    ...11β-HSD1 and the heartg a gray and others Review R1–R131 58: Open Access Abstract Corticosteroids influence the development and function of the heart and its response to injury and pressure overload via actions on glucocorticoid (GR) and mineralocorticoid (MR) receptors. Systemic corticosteroid conc ~~~
    OPEN ACCESS ARTICLE
  2. Research:
    • Ewa Harasim-Symbor,
    • Karolina Konstantynowicz-Nowicka,
    • and Adrian Chabowski
    Additive effects of dexamethasone and palmitate on hepatic lipid accumulation and secretion J Mol Endocrinol 57 (4) 261-273, doi: 10.1530/JME-16-0108 first published on 5 October 2016
    ...11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess. PNAS 111 E2482–E2491. (doi:10.1073/ pnas.1323681111) Nieuwenhuis B, Lüth A, Chun J, Huwiler A, Pfeilschifter J, SchäferKorting M & Kleuser B 2009 Involvement of the ABC-transporter ABCC1 and the sphi ~~~
  3. Research:
    • Irit Hochberg,
    • Innocence Harvey,
    • Quynh T Tran,
    • Erin J Stephenson,
    • Ariel L Barkan,
    • Alan R Saltiel,
    • William F Chandler,
    • and Dave Bridges
    Gene expression changes in subcutaneous adipose tissue due to Cushing's disease J Mol Endocrinol 55 (2) 81-94, doi: 10.1530/JME-15-0119 first published on 6 July 2015
    ...11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess . PNAS 111 E2482 – E2491 . ( doi:10.1073/pnas.1323681111 ). ↵ Ntali G , Grossman A & Karavitaki N 2015 Clinical and biochemical manifestations of Cushing's . Pituitary 18 181 – 187 . ( doi:10.1007 ~~~
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  4. Research:
    • Leping Zhao,
    • Yong Pan,
    • Kesong Peng,
    • Zhe Wang,
    • Jieli Li,
    • Dan Li,
    • Chao Tong,
    • Yi Wang,
    • and Guang Liang
    Inhibition of 11β-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice J Mol Endocrinol 55 (2) 119-131, doi: 10.1530/JME-14-0268 first published on 28 July 2015
    ...11β-HSD1 reductase IC50 (μM) agsupplemented with 10% heat-inactivated FBS in humidified 37 8C and 5% CO2 condition. Chinese harmary ovary cell line with overexpression of HSD11B1 gene (CHO-hsHSD11B1 cells) was a gift from Prof. Renshan Ge (Population Council, New York, NY, USA) and cultured in DMEM ~~~
  5. Research:
    • Ji Seon Park,
    • Su Jung Bae,
    • Sik-Won Choi,
    • You Hwa Son,
    • Sung Bum Park,
    • Sang Dal Rhee,
    • Hee Youn Kim,
    • Won Hoon Jung,
    • Seung Kyu Kang,
    • Jin Hee Ahn,
    • Seong Hwan Kim,
    • and Ki Young Kim
    A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation J Mol Endocrinol 52 (2) 191-202, doi: 10.1530/JME-13-0177 first published on 20 January 2014
    ...11β-HSD1 inhibitor. Cellular 11β-HSD1 activity was tested based on a homogeneous time-resolved fluorescence method. Oral glucose tolerance test (OGTT) and insulin tolerance test (ITT) levels were measured in diet-induced obese (DIO)-C57BL/6 mice administered KR-67500 (50 mg/kg per day, p.o.) for 28 ~~~
  6. Research:
    • Shirlene X Ong,
    • Keefe Chng,
    • Michael J Meaney,
    • and Jan P Buschdorf
    Decreased hippocampal mineralocorticoid:glucocorticoid receptor ratio is associated with low birth weight in female cynomolgus macaque neonates J Mol Endocrinol 51 (1) 59-67, doi: 10.1530/JME-12-0218 first published on 16 April 2013
    ...11β-HSD1 amygdala P = 0.02 Total GR cortex 11β-HSD1 cortexMR cortex C D E Fcampus and prefrontal cortex. Recently, the MR:GR ratio Published by Bioscientifica Ltd. JME-12-0218. critically reading the manuscript. Research S X ONG and others MR:GR ratio associated with low birth weight 51 :1 65was fou ~~~
  7. Research:
    • Cristina L Esteves,
    • Val Kelly,
    • Valérie Bégay,
    • Simon G Lillico,
    • Achim Leutz,
    • Jonathan R Seckl,
    • and Karen E Chapman
    Stable conditional expression and effect of C/EBPβ-LIP in adipocytes using the pSLIK system J Mol Endocrinol 51 (1) 91-98, doi: 10.1530/JME-13-0029 first published on 25 April 2013
    ...11β-HSD1 (Mm00476182_m1), PEPCK (Mm01247058_m1), FABP4 (Mm00445878_m1) and asparagine synthetase (Mm00803785_m1). TATA binding protein (TBP; Mm00446973_m1) was used as internal control and did not change with treatment or between groups. Statistical analysis All data were analysed by Student's t -te ~~~
    OPEN ACCESS ARTICLE
  8. Research:
    • Hanze Du,
    • Limei Liu,
    • Ying Wang,
    • Yuichi Nakagawa,
    • Alexei Lyzlov,
    • Kabirullah Lutfy,
    • Theodore C Friedman,
    • Xiaozhong Peng,
    • and Yanjun Liu
    Specific reduction of G6PT may contribute to downregulation of hepatic 11β-HSD1 in diabetic mice J Mol Endocrinol 50 (2) 167-178, doi: 10.1530/JME-12-0223 first published on 24 December 2012
    ...11β-HSD1 GAPDH Control ASO Control ASO 60A db/+ db/db β-H tiv ity to sio Control ASO Control ASO Control ASO Figure 4 The alterations of 11b-HSD1 activity and gene expression in the liver of db/C and db/db mice treated with G6PT ASO or ASO control. (A) 11b-HSD1 reductase activity was measured in mou ~~~
  9. Research:
    • Juan Liu,
    • Xiaocen Kong,
    • Long Wang,
    • Hanmei Qi,
    • Wenjuan Di,
    • Xiao Zhang,
    • Lin Wu,
    • Xia Chen,
    • Jing Yu,
    • Juanmin Zha,
    • Shan Lv,
    • Aisen Zhang,
    • Peng Cheng,
    • Miao Hu,
    • Yujie Li,
    • Jianhua Bi,
    • Yan Li,
    • Fang Hu,
    • Yi Zhong,
    • Yong Xu,
    • and Guoxian Ding
    Essential roles of 11β-HSD1 in regulating brown adipocyte function J Mol Endocrinol 50 (1) 103-113, doi: 10.1530/JME-12-0099 first published on 29 November 2012
    ...11β-HSD1 Research J LIU, X KONG, L WANG and others 11b-HSD1 and brown adipocyte 50 :1 106function Previously, we have found that expression of BAT-specific genes was significantly decreased in dexamethasone-Bioscience) per well for measurement of oxygen consumption on an XF24 respirometer (Seahorse ~~~
  10. Review:
    • Amanda J Rickard and
    • Morag J Young
    Corticosteroid receptors, macrophages and cardiovascular disease J Mol Endocrinol 42 (6) 449-459, doi: 10.1677/JME-08-0144 first published on 21 January 2009
    ...11β-HSD1 in pro-inflammatory properties in macrophages . FEBS Letters 581 349 – 354 . ↵ Kaden JJ , Bickelhaupt S , Grobholz R , Haase KK , Sarikoc A , Kilic R , Brueckmann M , Lang S , Zahn I , Vahl C et al. 2004 Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulate aortic ~~~
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