-
Hyperandrogenämie – Diagnostik und Therapiekonzepte
Christoph Keck and Sabine Elisabeth Segerer
Der Gynäkologe
(2015)
48 :891
-
Conversion of dehydroepiandrosterone sulfate at physiological plasma concentration into estrogens in MCF-7 cells
J.C Le Bail, H Lotfi, L Charles, D Pépin, and G Habrioux
Steroids
(2002)
67 :1057
-
Concurrent estrogen action was essential for maximal progestin effect in oral contraceptives
Yukiko Bono, Satoru Kyo, Tohru Kiyono, Yasunari Mizumoto, Mitsuhiro Nakamura, Yoshiko Maida, Masahiro Takakura, and Hiroshi
Fujiwara
Fertility and Sterility
(2014)
101 :1337
-
Combined blockade of testicular and locally made androgens in prostate cancer: A highly significant medical progress based
upon intracrinology
Fernand Labrie
The Journal of Steroid Biochemistry and Molecular Biology
(2015)
145 :144
-
Expression of 17β-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines
T. Šmuc and T. Lanišnik Rižner
Chemico-Biological Interactions
(2009)
178 :228
-
Deletion of 12 carboxyl-terminal residues from pig 3α/β,20β-hydroxysteroid dehydrogenase affects steroid metabolism
Shizuo Nakajin, Masaya Itoda, Shuji Ohno, Noriko Takase, Satoshi Toyoshima, and Michael E Baker
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
(2001)
1550 :175
-
Androgens and Breast Cancer in Men and Women
Constantine Dimitrakakis
Endocrinology and Metabolism Clinics of North America
(2011)
40 :533
-
Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
WenChieh Chen, Diane Thiboutot, and Christos C. Zouboulis
Journal of Investigative Dermatology
(2002)
119 :992
-
Cytochrome P450 17A1 inhibitor abiraterone attenuates cellular growth of prostate cancer cells independently from androgen
receptor signaling by modulation of oncogenic and apoptotic pathways
HANNAH GROSSEBRUMMEL, TILMANN PETER, ROBERT MANDELKOW, MARTIN WEISS, DAMIAN MUZZIO, UWE ZIMMERMANN, REINHARD WALTHER, FEDERICO
JENSEN, CORNELIUS KNABBE, MAREK ZYGMUNT, MARTIN BURCHARDT, and MATTHIAS B. STOPE
International Journal of Oncology
(2016)
48 :793
-
Inverse Regulation of DHT Synthesis Enzymes 5α-Reductase Types 1 and 2 by the Androgen Receptor in Prostate Cancer
Étienne Audet-Walsh, Tracey Yee, Ingrid S. Tam, and Vincent Giguère
Endocrinology
(2017)
158 :1015
-
Expression of Enzymes Involved in Estrogen Metabolism in Human Prostate
Yasukazu Takase, Marie-Hélène Lévesque, Van Luu-The, Mohamed El-Alfy, Fernand Labrie, and Georges Pelletier
Journal of Histochemistry & Cytochemistry
(2006)
54 :911
-
The association of endogenous sex hormones with lipoprotein subfraction profile in the Multi-Ethnic Study of Atherosclerosis
Dhananjay Vaidya, Adrian Dobs, Susan M. Gapstur, Sherita Hill Golden, Arlene Hankinson, Kiang Liu, and Pamela Ouyang
Metabolism
(2008)
57 :782
-
Comparative Enzymology of 11β-Hydroxysteroid Dehydrogenase Type 1 from Glucocorticoid Resistant (Guinea Pig)VersusSensitive
(Human) Species
Naeem Shafqat, Björn Elleby, Stefan Svensson, Jawed Shafqat, Hans Jörnvall, Lars Abrahmsen, and Udo Oppermann
Journal of Biological Chemistry
(2003)
278 :2030
-
Liquid chromatography–mass spectrometry (LC–MS) of steroid hormone metabolites and its applications
Trevor M. Penning, Seon-Hwa Lee, Yi Jin, Alejandro Gutierrez, and Ian A. Blair
The Journal of Steroid Biochemistry and Molecular Biology
(2010)
121 :546
-
A new polymorphism in the coding region of exon four in HSD17B2 in relation to risk of sporadic and hereditary breast cancer
Agneta Jansson, Jonas Carlsson, Anette Olsson, Petter Storm, Sara Margolin, Cecilia Gunnarsson, Marie Stenmark-Askmalm, Annika
Lindblom, Bengt Persson, and Olle Stål
Breast Cancer Research and Treatment
(2007)
106 :57
-
Effects of progestins on local estradiol biosynthesis and action in the Z-12 endometriotic epithelial cell line
Nataša Beranič and Tea Lanišnik Rižner
The Journal of Steroid Biochemistry and Molecular Biology
(2012)
132 :303
-
Current status on development of steroids as anticancer agents
Atul Gupta, B. Sathish Kumar, and Arvind S. Negi
The Journal of Steroid Biochemistry and Molecular Biology
(2013)
137 :242
-
Hydroxysteroid dehydrogenases: ancient and modern regulators of adrenal and sex steroid action
Michael E. Baker
Molecular and Cellular Endocrinology
(2001)
175 :1
-
The biological actions of estrogens on skin
M. J. Thornton
Experimental Dermatology
(2002)
11 :487
-
Synthesis of Two Estradiol-Imidazole C-Ribonucleoside Hybrid Compounds Exhibiting Inhibitory Effects against Type 1 17β-Hydroxysteroid
Dehydrogenase
Shinya Harusawa, Chihiro Kojima, Kensuke Fujii, Yuusaku Yamashita, Tomoya Tanaka, Lisa Araki, Toshinobu Yoshimura, Minoru
Sakaguchi, Yoshihide Usami, and Masanori Takaoka
HETEROCYCLES
(2010)
81 :2817
-
Major enzymes controlling the androgenic pressure in the developing lung
Yves Tremblay and Pierre R. Provost
The Journal of Steroid Biochemistry and Molecular Biology
(2013)
137 :93
-
Estrogen in men: effects on bone accrual, maintenance and prevention of bone loss
Luigi Gennari, Ranuccio Nuti, and John P Bilezikian
Expert Review of Endocrinology & Metabolism
(2006)
1 :281
-
The Metabolism, Analysis, and Targeting of Steroid Hormones in Breast and Prostate Cancer
Cameron P. Capper, James M. Rae, and Richard J. Auchus
Hormones and Cancer
(2016)
7 :149
-
Bicyclic Substituted Hydroxyphenylmethanone Type Inhibitors of 17 β-Hydroxysteroid Dehydrogenase Type 1 (17 β-HSD1): The Role
of the Bicyclic Moiety
Alexander Oster, Tobias Klein, Claudia Henn, Ruth Werth, Sandrine Marchais-Oberwinkler, Martin Frotscher, and Rolf W. Hartmann
ChemMedChem
(2011)
6 :476
-
Dehydroepiandrosterone (DHEA) is an anabolic steroid like dihydrotestosterone (DHT), the most potent natural androgen, and
tetrahydrogestrinone (THG)
Fernand Labrie, Van Luu-The, Céline Martel, Ariel Chernomoretz, Ezequiel Calvo, Jean Morissette, and Claude Labrie
The Journal of Steroid Biochemistry and Molecular Biology
(2006)
100 :52
-
Metabolic conversion as a pre-receptor control mechanism for lipophilic hormones
Stefan Nobel, Lars Abrahmsen, and Udo Oppermann
European Journal of Biochemistry
(2001)
268 :4113
-
Neuroendocrine–immune interactions in synovitis
Maurizio Cutolo, Rainer H Straub, and Johannes WJ Bijlsma
Nature Clinical Practice Rheumatology
(2007)
3 :627
-
Immunoexpression of aromatase cytochrome P450 and 17β-hydroxysteroid dehydrogenase in women’s ovaries after menopause
Agnieszka Brodowska, Jacek Brodowski, Maria Laszczyńska, Sylwia Słuczanowska-Głąbowska, Bogdan Rumianowski, Iwona Rotter,
Andrzej Starczewski, and Mariusz Z Ratajczak
Journal of Ovarian Research
(2014)
7 :52
-
Mammographic densities during the menopausal transition
Janet R. Guthrie, Roger L. Milne, John L. Hopper, Jennifer Cawson, Lorraine Dennerstein, and Henry G. Burger
Menopause
(2007)
14 :208
-
Estrogen and androgen signaling in the pathogenesis of BPH
Clement K. M. Ho and Fouad K. Habib
Nature Reviews Urology
(2011)
8 :29
-
Structure-based Phylogenetic Analysis of Short-chain Alcohol Dehydrogenases and Reclassification of the 17beta-Hydroxysteroid
Dehydrogenase Family
Rainer Breitling, Daniela Laubner, and Jerzy Adamski
Molecular Biology and Evolution
(2001)
18 :2154
-
Mechanism for normal splenic T lymphocyte functions in proestrus females after trauma: enhanced local synthesis of 17β-estradiol
T. S. Anantha Samy, Rui Zheng, Takeshi Matsutani, Loring W. Rue, Kirby I. Bland, and Irshad H. Chaudry
American Journal of Physiology-Cell Physiology
(2003)
285 :C139
-
Computational investigation of the binding mode of bis(hydroxylphenyl)arenes in 17β-HSD1: molecular dynamics simulations,
MM-PBSA free energy calculations, and molecular electrostatic potential maps
Matthias Negri, Maurizio Recanatini, and Rolf W. Hartmann
Journal of Computer-Aided Molecular Design
(2011)
25 :795
-
On the inhibitory action of 29 drugs having side effect gynecomastia on estrogen production
Takashi Satoh, Shinji Itoh, Toshio Seki, Shungo Itoh, Norikazu Nomura, and Itsuo Yoshizawa
The Journal of Steroid Biochemistry and Molecular Biology
(2002)
82 :209
-
AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate
cancer cells
Shaobin Wang, Qing Yang, Kar-Ming Fung, and Hsueh-Kung Lin
Molecular and Cellular Endocrinology
(2008)
289 :60
-
Activities of steroid metabolic enzymes in secretory endometria from untreated women with Polycystic Ovary Syndrome
Luis Leon, Ketty Bacallao, Fernando Gabler, Carmen Romero, Luis Valladares, and Margarita Vega
Steroids
(2008)
73 :88
-
Chemical synthesis andin vitrobiological evaluation of a phosphorylated bisubstrate inhibitor of type 3 17β-hydroxysteroid
dehydrogenase
Marie Bérubé and Donald Poirier
Journal of Enzyme Inhibition and Medicinal Chemistry
(2007)
22 :201
-
Expression of steroidogenic enzymes and synthesis of sex steroid hormones from DHEA in skeletal muscle of rats
Katsuji Aizawa, Motoyuki Iemitsu, Seiji Maeda, Subrina Jesmin, Takeshi Otsuki, Chishimba N. Mowa, Takashi Miyauchi, and Noboru
Mesaki
American Journal of Physiology-Endocrinology and Metabolism
(2007)
292 :E577
-
Transcript level of AKR1C3 is down-regulated in gastric cancer
Bartosz Adam Frycz, Dawid Murawa, Maciej Borejsza-Wysocki, Mateusz Wichtowski, Arkadiusz Spychała, Ryszard Marciniak, Paweł
Murawa, Michał Drews, and Paweł Piotr Jagodziński
Biochemistry and Cell Biology
(2016)
94 :138
-
Androgen action and metabolism in prostate cancer
Sean M. Green, Elahe A. Mostaghel, and Peter S. Nelson
Molecular and Cellular Endocrinology
(2012)
360 :3
-
Biochemistry and Reproductive Endocrinology of Estrogen Sulfotransferase
WEN-CHAO SONG
Annals of the New York Academy of Sciences
(2006)
948 :43
-
Effects of testosterone on cardiomyocyte calcium homeostasis and contractile function in female rats
Ronald D. Beesley, Bradley M. Palmer, Peter R. Casson, and Michael J. Toth
Experimental Physiology
(2013)
98 :161
-
Substrate inhibition of 17β-HSD1 in living cells and regulation of 17β-HSD7 by 17β-HSD1 knockdown
Hui Han, Jean-François Thériault, Guang Chen, and Sheng-Xiang Lin
The Journal of Steroid Biochemistry and Molecular Biology
(2017)
172 :36
-
Differential metabolism of androst-5-ene-3β,17β-diol between rats, canines, monkeys and humans
Clarence N. Ahlem, Steven K. White, Theodore M. Page, and James M. Frincke
Steroids
(2011)
76 :669
-
An Hsp27-related, Dominant-negative-acting Intracellular Estradiol-binding Protein
Hong Chen, Martin Hewison, Bing Hu, Manju Sharma, Zijie Sun, and John S. Adams
Journal of Biological Chemistry
(2004)
279 :29944
-
The enigmatic relationship between epiphyseal fusion and bone development in primates
Conrad Stephen Brimacombe
Evolutionary Anthropology: Issues, News, and Reviews
(2017)
26 :325
-
CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders
Xiuying Bai, Dengshun Miao, Sophia Xiao, Dinghong Qiu, René St-Arnaud, Martin Petkovich, Ajay Gupta, David Goltzman, and Andrew
C. Karaplis
Journal of Clinical Investigation
(2016)
126 :667
-
17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: Protein structures, functions, and recent progress in
inhibitor development
Sandrine Marchais-Oberwinkler, Claudia Henn, Gabriele Möller, Tobias Klein, Matthias Negri, Alexander Oster, Alessandro Spadaro,
Ruth Werth, Marie Wetzel, Kuiying Xu, Martin Frotscher, Rolf W. Hartmann, and Jerzy Adamski
The Journal of Steroid Biochemistry and Molecular Biology
(2011)
125 :66
-
Bayesian local influence of semiparametric structural equation models
Ming Ouyang, Xiaodong Yan, Ji Chen, Niansheng Tang, and Xinyuan Song
Computational Statistics & Data Analysis
(2017)
111 :102
-
Downregulation of estrogen-metabolizing 17β-hydroxysteroid dehydrogenase Type 2 expression correlates inversely with Ki67
proliferation marker in colon-cancer development
Olayiwola O. Oduwole, Veli V. Isomaa, Pasi A. Nokelainen, Frej Stenbäck, and Pirkko T. Vihko
International Journal of Cancer
(2002)
97 :1
-
Evolution of adrenal and sex steroid action in vertebrates: a ligand-based mechanism for complexity
Michael E. Baker
BioEssays
(2003)
25 :396
-
Omic studies reveal the pathogenic lipid droplet proteins in non-alcoholic fatty liver disease
Xuelin Zhang, Yang Wang, and Pingsheng Liu
Protein & Cell
(2017)
8 :4
-
Androgens and the breast
Constantine Dimitrakakis and Carolyn Bondy
Breast Cancer Research
(2009)
11 :
-
Role of androgens in female genital sexual arousal: receptor expression, structure, and function
Abdulmaged M Traish, Noel Kim, Kweonsik Min, Ricardo Munarriz, and Irwin Goldstein
Fertility and Sterility
(2002)
77 :11
-
Dehydroepiandrosterone, androgens and the mammary gland
Fernand Labrie
Gynecological Endocrinology
(2006)
22 :118
-
Expression of steroidogenic enzymes in human sebaceous glands
T. Inoue, Y. Miki, S. Kakuo, A. Hachiya, T. Kitahara, S. Aiba, C. C. Zouboulis, and H. Sasano
Journal of Endocrinology
(2014)
222 :301
-
New inhibitors of 17β-hydroxysteroid dehydrogenase type 1
Josef Messinger, Leena Hirvelä, Bettina Husen, Lauri Kangas, Pasi Koskimies, Olli Pentikäinen, Pauli Saarenketo, and Hubert
Thole
Molecular and Cellular Endocrinology
(2006)
248 :192
-
Inhibition of type 2 17β-hydroxysteroid dehydrogenase by estradiol derivatives bearing a lactone on the D-ring: structure–activity
relationships
Patrick Bydal, Serge Auger, and Donald Poirier
Steroids
(2004)
69 :325
-
Exemestane in the Adjuvant Treatment of Breast Cancer in Postmenopausal Women
Muaiad Kittaneh and Stefan Glück
Breast Cancer: Basic and Clinical Research
(2011)
5 :BCBCR.S6234
-
COMMENTARY: Are the Endocrine Society's Clinical Practice Guidelines on Androgen Therapy in Women Misguided? A Commentary
Abdulmaged Traish, Andre T. Guay, Richard F. Spark, and the Testosterone Therapy in Women Study Group
The Journal of Sexual Medicine
(2007)
4 :1223
-
Expression analysis of the genes involved in estradiol and progesterone action in human ovarian endometriosis
Tina Šmuc, Martina Ribič Pucelj, Jasna Šinkovec, Bettina Husen, Hubert Thole, and Tea Lanišnik Rižner
Gynecological Endocrinology
(2007)
23 :105
-
17Beta-hydroxysteroid dehydrogenase enzymes and breast cancer
Agneta Jansson
The Journal of Steroid Biochemistry and Molecular Biology
(2009)
114 :64
-
A semiparametric Bayesian approach for structural equation models
Xin-Yuan Song, Jun-Hao Pan, Timothy Kwok, Liesbeth Vandenput, Claes Ohlsson, and Ping-Chung Leung
Biometrical Journal
(2010)
52 :314
-
The Impact of Germline Genetic Variations in Hydroxysteroid (17-Beta) Dehydrogenases on Prostate Cancer Outcomes After Prostatectomy
Étienne Audet-Walsh, Judith Bellemare, Louis Lacombe, Yves Fradet, Vincent Fradet, Pierre Douville, Chantal Guillemette, and
Éric Lévesque
European Urology
(2012)
62 :88
-
Production of sex steroid hormones from DHEA in articular chondrocyte of rats
Satsuki Takeuchi, Naoki Mukai, Tetsuya Tateishi, and Shumpei Miyakawa
American Journal of Physiology-Endocrinology and Metabolism
(2007)
293 :E410
-
3β-Alkyl-androsterones as inhibitors of type 3 17β-hydroxysteroid dehydrogenase: Inhibitory potency in intact cells, selectivity
towards isoforms 1, 2, 5 and 7, binding affinity for steroid receptors, and proliferative/antiproliferative activities on
AR+ and ER+ cell lines
Béatrice Tchédam Ngatcha, Yannick Laplante, Fernand Labrie, Van Luu-The, and Donald Poirier
Molecular and Cellular Endocrinology
(2006)
248 :225
-
Molecular Cloning of a Novel Type of Rat Cytoplasmic 17β-Hydroxysteroid Dehydrogenase Distinct from the Type 5 Isozyme
Shuhei Ishikura, Kengo Matsumoto, Masaharu Sanai, Kenji Horie, Toshiyuki Matsunaga, Kazuo Tajima, Ossama El-Kabbani, and Akira
Hara
The Journal of Biochemistry
(2006)
139 :1053
-
Sex hormones and quantitative ultrasound parameters at the heel in men and women from the general population
Konrad Pätzug, Nele Friedrich, Hanna Kische, Anke Hannemann, Henry Völzke, Matthias Nauck, Brian G. Keevil, and Robin Haring
Bone Reports
(2017)
7 :51
-
The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis
Takayoshi Inoue, Yasuhiro Miki, Keiko Abe, Masahito Hatori, Masami Hosaka, Yoshiyuki Kariya, Shingo Kakuo, Tsutomu Fujimura,
Akira Hachiya, Setsuya Aiba, and Hironobu Sasano
Molecular and Cellular Endocrinology
(2011)
344 :35
-
Steroidal Metabolites Transformed by Marchantia polymorpha Cultures Block Breast Cancer Estrogen Biosynthesis
Mohamed-Elamir F. Hegazy, Amira M. Gamal-Eldeen, Ali M. El-Halawany, Abou El-Hamd H. Mohamed, and Paul W. Paré
Cell Biochemistry and Biophysics
(2012)
63 :85
-
Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer
Karen E. Knudsen and Trevor M. Penning
Trends in Endocrinology & Metabolism
(2010)
21 :315
-
Intracrine sex steroid synthesis and signaling in human epidermal keratinocytes and dermal fibroblasts
Elena Pomari, Luisa Dalla Valle, Paolo Pertile, Lorenzo Colombo, and M. Julie Thornton
The FASEB Journal
(2015)
29 :508
-
Effects of valproate and carbamazepine monotherapy on neuroactive steroids, their precursors and metabolites in adult men
with epilepsy
Martin Hill, Jana Zárubová, Petr Marusič, Jana Vrbíková, Marta Velíková, Radmila Kancheva, Lyudmila Kancheva, Jana Kubátová,
Michaela Dušková, Ludmila Zamrazilová, Hana Kazihnitková, Kateřina Šimůnková, and Luboslav Stárka
The Journal of Steroid Biochemistry and Molecular Biology
(2010)
122 :239
-
Acute and chronic effects of genistein, tyrphostin and lavendustin A on steroid synthesis in luteinized human granulosa cells
S. A. Whitehead, J. E. Cross, C. Burden, and M. Lacey
Human Reproduction
(2002)
17 :589
-
Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung
Eric Boucher, Pierre R Provost, and Yves Tremblay
BMC Research Notes
(2014)
7 :119
-
Differential expression of 17?-hydroxysteroid dehydrogenase isozyme genes in prostate cancer and noncancer tissues
Eitetsu Koh, Toru Noda, Jiro Kanaya, and Mikio Namiki
The Prostate
(2002)
53 :154
-
Perimenopausal regulation of steroidogenesis in the nonhuman primate
Krystina G. Sorwell, Steven G. Kohama, and Henryk F. Urbanski
Neurobiology of Aging
(2012)
33 :1487.e1
-
Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome
Clarence N. Ahlem, Dominick L. Auci, Ferdinando Nicoletti, Raymond Pieters, Michael R. Kennedy, Theodore M. Page, Christopher
L. Reading, Elena Y. Enioutina, and James M. Frincke
The Journal of Steroid Biochemistry and Molecular Biology
(2011)
126 :87
-
Glucocorticoid metabolism in the developing lung: Adrenal-like synthesis pathway
Pierre R. Provost, Eric Boucher, and Yves Tremblay
The Journal of Steroid Biochemistry and Molecular Biology
(2013)
138 :72
-
Androgens and mammary growth and neoplasia
Constantine Dimitrakakis, Jian Zhou, and Carolyn A Bondy
Fertility and Sterility
(2002)
77 :26
-
Intracrine Control of Estrogen Action in Human Gestational Tissues at Parturition
Gemma Madsen, Tamas Zakar, Ursula Manuelpillai, Euan Wallace, Kenneth Kwek, George S. H. Yeo, Roger Smith, and Sam Mesiano
Journal of the Society for Gynecologic Investigation
(2004)
11 :213
-
Possible metformin effect on adrenal androgens during pretreatment and IVF cycle in women with polycystic ovary syndrome
Sigrun B. Kjøtrød, Arne Sunde, Vidar von Düring, and Sven M. Carlsen
Fertility and Sterility
(2009)
91 :500
-
Genomic and non-genomic actions of sex steroids in the growth plate
Marcel Karperien, Bram C. J. van der Eerden, and Jan Maarten Wit
Pediatric Nephrology
(2005)
20 :323
-
Expression and regulation of estrogen-converting enzymes in ectopic human endometrial tissue
Sabine Fechner, Bettina Husen, Hubert Thole, Markus Schmidt, Isabella Gashaw, Rainer Kimmig, Elke Winterhager, and Ruth Grümmer
Fertility and Sterility
(2007)
88 :1029
-
SDR-type human hydroxysteroid dehydrogenases involved in steroid hormone activation
Xiaoqiu Wu, Petra Lukacik, Kathryn L. Kavanagh, and Udo Oppermann
Molecular and Cellular Endocrinology
(2007)
265-266 :71
-
Current knowledge of the multifunctional 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1)
Wanhong He, Misra Gauri, Tang Li, Ruixuan Wang, and Sheng-Xiang Lin
Gene
(2016)
588 :54
-
Reductive 17β-hydroxysteroid dehydrogenases in the sulfatase pathway: Critical in the cell proliferation of breast cancer
Juliette A. Aka, Mausumi Mazumdar, and Sheng-Xiang Lin
Molecular and Cellular Endocrinology
(2009)
301 :183
-
Localization of the Androgen‐Synthesizing Enzymes, Androgen Receptor, and Sex Steroids in the Vagina: Possible Implications
for the Treatment of Postmenopausal Sexual Dysfunction
Jonathan Bertin, Alain Y. Dury, Johanne Ouellet, Georges Pelletier, and Fernand Labrie
The Journal of Sexual Medicine
(2014)
11 :1949
-
Gynäkologische Endokrinologie verschiedener Lebensphasen
A. T. Teichmann, C. Wieg, and H. Wieland
Der Gynäkologe
(2006)
39 :580
-
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain
its over-expression in breast cancer
Michael C. Byrns, Ling Duan, Seon Hwa Lee, Ian A. Blair, and Trevor M. Penning
The Journal of Steroid Biochemistry and Molecular Biology
(2010)
118 :177
-
17β-Hydroxysteroid dehydrogenase inhibitors: a patent review
Donald Poirier
Expert Opinion on Therapeutic Patents
(2010)
20 :1123
-
Aromatase, estrone sulfatase, and 17β-hydroxysteroid dehydrogenase: Structure–function studies and inhibitor development
Yanyan Hong and Shiuan Chen
Molecular and Cellular Endocrinology
(2011)
340 :120
-
DHEA and Its Transformation into Androgens and Estrogens in Peripheral Target Tissues: Intracrinology
Fernand Labrie, Van Luu-The, Claude Labrie, and Jacques Simard
Frontiers in Neuroendocrinology
(2001)
22 :185
-
Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human
breast cancer cells (MCF-7Ca) in vivo
Y. H. Ju, D. R. Doerge, K. A. Woodling, J. A. Hartman, J. Kwak, and W. G. Helferich
Carcinogenesis
(2008)
29 :2162
-
Type 5 17β-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): Role in breast cancer and inhibition by non-steroidal
anti-inflammatory drug analogs
Michael C. Byrns and Trevor M. Penning
Chemico-Biological Interactions
(2009)
178 :221
-
Clinical, endocrine, and molecular findings in 17β -hydroxysteroid dehydrogenase type 3 deficiency
M. F. Faienza, L. Giordani, M. Delvecchio, and L. Cavallo
Journal of Endocrinological Investigation
(2008)
31 :85
-
Oestrogens and puberty
Laura C. Alonso and Robert L. Rosenfield
Best Practice & Research Clinical Endocrinology & Metabolism
(2002)
16 :13
-
Regulation of 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4 Isomerase: A Review
Martin Rasmussen, Bo Ekstrand, and Galia Zamaratskaia
International Journal of Molecular Sciences
(2013)
14 :17926
-
Acute Dehydroepiandrosterone (DHEA) Effects on Sexual Arousal in Postmenopausal Women
Lucianne Hackbert and Julia R. Heiman
Journal of Women's Health & Gender-Based Medicine
(2002)
11 :155
-
Immunohistochemical analysis of 17β-hydroxysteroid dehydrogenase isozymes in human ovarian surface epithelium and epithelial
ovarian carcinoma
Ken-ichi Motohara, Hironori Tashiro, Yumiko Taura, Takashi Ohba, and Hidetaka Katabuchi
Medical Molecular Morphology
(2010)
43 :197
-
C21-steroids inactivation and glucocorticoid synthesis in the developing lung
Eric Boucher, Pierre R. Provost, and Yves Tremblay
The Journal of Steroid Biochemistry and Molecular Biology
(2015)
147 :70
-
Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism
Qing Ji, Lilly Chang, David VanDenBerg, Frank Z. Stanczyk, and Andrew Stolz
The Prostate
(2003)
54 :275
-
Variants in Estrogen Biosynthesis Genes, Sex Steroid Hormone Levels, and Endometrial Cancer: A HuGE Review
Sara H. Olson, Elisa V. Bandera, and Irene Orlow
American Journal of Epidemiology
(2007)
165 :235
-
In vivo mouse model for analysis of hydroxysteroid (17β) dehydrogenase 1 inhibitors
Tarja Lamminen, Taija Saloniemi, Kaisa Huhtinen, Pasi Koskimies, Josef Messinger, Bettina Husen, Hubert Thole, and Matti Poutanen
Molecular and Cellular Endocrinology
(2009)
301 :158
-
Actions d’un progestatif dérivé de la 19-norprogestérone sur la glande mammaire : le nomégestrol acétate
G. André
Journal de Gynécologie Obstétrique et Biologie de la Reproduction
(2005)
34 :69
-
Substrate Specificity of Human 3(20)α-Hydroxysteroid Dehydrogenase for Neurosteroids and Its Inhibition by Benzodiazepines
Noriyuki Usami, Tomohiro Yamamoto, Syunichi Shintani, Yu Higaki, Shuhei Ishikura, Yoshihiro Patagiri, and Akira Hara
Biological & Pharmaceutical Bulletin
(2002)
25 :441
-
Decreased 5α-dihydrotestosterone catabolism suppresses T lymphocyte functions in males after trauma-hemorrhage
Rui Zheng, T. S. Anantha Samy, Christian P. Schneider, Loring W. Rue, Kirby I. Bland, and Irshad H. Chaudry
American Journal of Physiology-Cell Physiology
(2002)
282 :C1332
-
Human hydroxysteroid dehydrogenases and pre-receptor regulation: Insights into inhibitor design and evaluation
Trevor M. Penning
The Journal of Steroid Biochemistry and Molecular Biology
(2011)
125 :46
-
Bayesian Analysis of Mixture Structural Equation Models With an Unknown Number of Components
Hefei Liu and Xin Yuan Song
Structural Equation Modeling: A Multidisciplinary Journal
(2018)
25 :41
-
Focused Libraries of 16-Substituted Estrone Derivatives and Modified E-Ring Steroids: Inhibitors of 17ß-Hydroxysteroid Dehydrogenase
Type 1
Nigel Vicker, Harshani R. Lawrence, Gillian M. Allan, Christian Bubert, Andrew Smith, Helena J. Tutill, Atul Purohit, Joanna M.
Day, Mary F. Mahon, Michael J. Reed, and Barry V. L. Potter
ChemMedChem
(2006)
1 :464
-
Neural transcriptome reveals molecular mechanisms for temporal control of vocalization across multiple timescales
Ni Y Feng, Daniel J Fergus, and Andrew H Bass
BMC Genomics
(2015)
16 :
-
Chemical Synthesis of (S)-Spiro(estradiol-17,2′-[1,4]oxazinan)-6′-one Derivatives Bearing Two Levels of Molecular Diversity
François Rouillard, Jenny Roy, and Donald Poirier
European Journal of Organic Chemistry
(2008)
2008 :2446
-
Characterization of the dehydroepiandrosterone (DHEA) metabolism via oxysterol 7α-hydroxylase and 17-ketosteroid reductase
activity in the human brain
Stephan Steckelbroeck, Matthias Watzka, Dieter Lütjohann, Paul Makiola, Alexander Nassen, Volkmar H. J. Hans, Hans Clusmann,
Annette Reissinger, Michael Ludwig, Lothar Siekmann, and Dietrich Klingmüller
Journal of Neurochemistry
(2002)
83 :713
-
Androgen-metabolizing enzymes: A structural perspective
Mahder Seifu Manenda, Charles Jérémie Hamel, Loreleï Masselot--Joubert, Marie-Ève Picard, and Rong Shi
The Journal of Steroid Biochemistry and Molecular Biology
(2016)
161 :54
-
Regulation of steroidogenesis in a primary pigmented nodular adrenocortical disease-associated adenoma leading to virilization
and subclinical Cushing's syndrome
J. Hofland, W. W. de Herder, L. Derks, L. J. Hofland, P. M. van Koetsveld, R. R. de Krijger, F. H. van Nederveen, A. Horvath,
C. A. Stratakis, F. H. de Jong, and R. A. Feelders
European Journal of Endocrinology
(2012)
168 :67
-
In vitro interactions between mammary fibroblasts (Hs 578Bst) and cancer epithelial cells (MCF-7) modulate aromatase, steroid
sulfatase and 17β-hydroxysteroid dehydrogenases
Xiaoqiang Wang, Xiaoye Sang, Caroline Diorio, Sheng-Xiang Lin, and Charles J. Doillon
Molecular and Cellular Endocrinology
(2015)
412 :339
-
The AR dependent cell cycle: Mechanisms and cancer relevance
Matthew J. Schiewer, Michael A. Augello, and Karen E. Knudsen
Molecular and Cellular Endocrinology
(2012)
352 :34
-
Studies on the Interactions between Drug and Estrogen. II. On the Inhibitory Effect of 29 Drugs Reported to Induce Gynecomastia
on the Oxidation of Estradiol at C-2 or C-17
Takashi Satoh, Haruka Munakata, Ken-ichi Fujita, Shinji Itoh, Shungo Itoh, Tetsuya Kamataki, and Itsuo Yoshizawa
Biological & Pharmaceutical Bulletin
(2003)
26 :695
-
Expression of Estrogen Sulfotransferase 1E1 and Steroid Sulfatase in Breast Cancer: A Immunohistochemical Study
D. Poisson Paré, D. Song, V. Luu-The, B. Han, S. Li, G. Liu, F Labrie, and G. Pelletier
Breast Cancer: Basic and Clinical Research
(2009)
3 :BCBCR.S2012
-
Differential effects of yolk testosterone and androstenedione in embryo development and nestling growth in the spotless starling
(Sturnus unicolor)
Jaime Muriel, Lorenzo Pérez-Rodríguez, Marisa Puerta, and Diego Gil
General and Comparative Endocrinology
(2013)
194 :175
-
Rational proteomics IV: modeling the primary function of the mammalian 17β-hydroxysteroid dehydrogenase type 8
Vladimir Z. Pletnev and William L. Duax
The Journal of Steroid Biochemistry and Molecular Biology
(2005)
94 :327
-
Steroid Hormone Transforming Aldo-Keto Reductases and Cancer
Trevor M. Penning and Michael C. Byrns
Annals of the New York Academy of Sciences
(2009)
1155 :33
-
TFOS DEWS II Sex, Gender, and Hormones Report
David A. Sullivan, Eduardo M. Rocha, Pasquale Aragona, Janine A. Clayton, Juan Ding, Blanka Golebiowski, Ulrike Hampel, Alison
M. McDermott, Debra A. Schaumberg, Sruthi Srinivasan, Piera Versura, and Mark D.P. Willcox
The Ocular Surface
(2017)
15 :284
-
Males With 17β-Hydroxysteroid Dehydrogenase Deficiency
Jacques Simard, Anne Marie Moisan, Laurence Calemard Michel, and Yves Morel
The Endocrinologist
(2003)
13 :195
-
Structure and function of human 17β-hydroxysteroid dehydrogenases
Petra Lukacik, Kathryn L. Kavanagh, and Udo Oppermann
Molecular and Cellular Endocrinology
(2006)
248 :61
-
Cellular, molecular and sexual dimorphic response to trauma-hemorrhage
Mashkoor A. Choudhry, Martin G. Schwacha, Takeshi Matsutani, Kirby I. Bland, and Irshad H. Chaudry
International Congress Series
(2003)
1255 :25
-
Synthesis of Simplified Hybrid Inhibitors of Type 1 17β-Hydroxysteroid Dehydrogenase via Cross-Metathesis and Sonogashira
Coupling Reactions
Marie Bérubé and Donald Poirier
Organic Letters
(2004)
6 :3127
-
Expression of the estrogen receptors and steroidogenic enzymes involved in estradiol formation in the monkey vagina
Jonathan Bertin, Johanne Ouellet, Alain Yves Dury, Georges Pelletier, and Fernand Labrie
American Journal of Obstetrics and Gynecology
(2014)
211 :499.e1
-
Mimicking postmenopausal steroid metabolism in breast cancer cell culture: Differences in response to DHEA or other steroids
as hormone sources
Dan Xu and Sheng-Xiang Lin
The Journal of Steroid Biochemistry and Molecular Biology
(2016)
161 :92
-
The intracrinology of breast cancer
Keely May McNamara and Hironobu Sasano
The Journal of Steroid Biochemistry and Molecular Biology
(2015)
145 :172
-
Riboflavin deficiency induces a significant change in proteomic profiles in HepG2 cells
Zhonghao Xin, Lingling Pu, Weina Gao, Yawen Wang, Jingyu Wei, Tala Shi, Zhanxin Yao, and Changjiang Guo
Scientific Reports
(2017)
7 :45861
-
Binding characteristics of [3H]Δ5-androstene-3β,17β-diol to a nuclear protein in the rabbit vagina
Abdulmaged M. Traish, Yue-Hua Huang, Kweonsik Min, Noel N. Kim, Ricardo Munarriz, and Irwin Goldstein
Steroids
(2004)
69 :71
-
The direct role of vitamin D on bone homeostasis
René St-Arnaud
Archives of Biochemistry and Biophysics
(2008)
473 :225
-
Human microsomal carbonyl reducing enzymes in the metabolism of xenobiotics: well-known and promising members of the SDR superfamily
Lucie Škarydová and Vladimír Wsól
Drug Metabolism Reviews
(2012)
44 :173
-
Estrogen Metabolism in the Equine Conceptus and Endometrium During Early Pregnancy in Relation to Estrogen Concentrations
in Yolk-Sac Fluid1
James I. Raeside, Heather L. Christie, Rick L. Renaud, Rudolf O. Waelchli, and Keith J. Betteridge
Biology of Reproduction
(2004)
71 :1120
-
Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women
F. Labrie, A. Bélanger, C. Labrie, B. Candas, L. Cusan, and J.L. Gomez
The Journal of Steroid Biochemistry and Molecular Biology
(2007)
107 :57
-
Characterisation of estrogenic 17β-hydroxysteroid dehydrogenase (17β-HSD) activity in the human brain
Stephan Steckelbroeck, Matthias Watzka, Annette Reissinger, Petra Wegener-Toper, Frank Bidlingmaier, Niklaas Bliesener, Volkmar
H.J. Hans, Hans Clusmann, Michael Ludwig, Lothar Siekmann, and Dietrich Klingmüller
The Journal of Steroid Biochemistry and Molecular Biology
(2003)
86 :79
-
Expression of sulfotransferase 1E1 in human prostate as studied by in situ hybridization and immunocytochemistry
Y. Takase, V. Luu-The, D. Poisson-Paré, F. Labrie, and G. Pelletier
The Prostate
(2007)
67 :405
-
Synchronous bilateral breast cancer in a male patient following hormone therapy for prostate cancer
Yuko Kijima, Heiji Yoshinaka, Munetsugu Hirata, Yoshihisa Umekita, Sumika Matsukita, Takashi Arima, Masayuki Nakagawa, Hizuru
Kumemura, Nobuo Hamada, Koichi Kaneko, Yawara Funasako, and Shoji Natsugoe
International Journal of Clinical Oncology
(2009)
14 :249
-
Disturbed estrogen and progesterone action in ovarian endometriosis
Tina Šmuc, Neli Hevir, Martina Ribič-Pucelj, Bettina Husen, Hubert Thole, and Tea Lanišnik Rižner
Molecular and Cellular Endocrinology
(2009)
301 :59
-
Testosterone and dehydroepiandrosterone sulphate levels and IVF/ICSI results
Batool Hossein Rashidi, Bita Hormoz, Ensiyeh Shahrokh Tehraninejad, Mamak Shariat, and Atossa Mahdavi
Gynecological Endocrinology
(2009)
25 :194
-
Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey
Mathias Leblanc, Claude Labrie, Alain Bélanger, Bernard Candas, and Fernand Labrie
The Journal of Steroid Biochemistry and Molecular Biology
(2002)
81 :159
-
The role of 17 beta-hydroxysteroid dehydrogenases
R Mindnich, G Möller, and J Adamski
Molecular and Cellular Endocrinology
(2004)
218 :7
-
Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance
in LNCaP prostate xenografts
Jennifer A. Locke, Colleen C. Nelson, Hans H. Adomat, Stephen C. Hendy, Martin E. Gleave, and Emma S. Tomlinson Guns
The Journal of Steroid Biochemistry and Molecular Biology
(2009)
115 :126
-
Basic Roles of Sex Steroid Hormones in Wound Repair with Focus on Estrogens (A Review)
Z. Čriepoková, L’. Lenhardt, and P. Gál
Folia Veterinaria
(2016)
60 :
-
Pharmacology And Therapeutic Effects of Dehydroepiandrosterone In Older Subjects
Sylvie Legrain and Laurence Girard
Drugs & Aging
(2003)
20 :949
-
Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3α-hydroxysteroid dehydrogenase/type
5 17β-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate
Hsueh-Kung Lin, Stephan Steckelbroeck, Kar-Ming Fung, Amy N. Jones, and Trevor M. Penning
Steroids
(2004)
69 :795
-
Co-evolution of steroidogenic and steroid-inactivating enzymes and adrenal and sex steroid receptors
Michael E. Baker
Molecular and Cellular Endocrinology
(2004)
215 :55
-
Estrogen metabolism by the equine embryo proper during the fourth week of pregnancy
J. I Raeside, H. L Christie, R. O Waelchli, and K. J Betteridge
Reproduction
(2009)
138 :953
-
Effect of dehydroepiandrosterone (DHEA) on vascular function in postmenopausal women with diabetes: a randomized controlled
trial
Amal Shibli-Rahhal, William Haynes, Christine Sinkey, and Joseph S Dillon
Journal of Diabetes Research and Clinical Metabolism
(2012)
1 :13
-
11β-Hydroxysteroid dehydrogenase-type 2 evolved from an ancestral 17β-Hydroxysteroid dehydrogenase-type 2
Michael E. Baker
Biochemical and Biophysical Research Communications
(2010)
399 :215
-
Molecular cloning and expression of 17β-hydroxysteroid dehydrogenase type 2 gene in Hu sheep
Chang Long Wang, Shi Jia Ying, Zi Yu Wang, Hui Jun Xing, Li Zhong Wang, Dong Yang He, Shen Hua Xiao, and Feng Wang
Molecular Biology Reports
(2013)
40 :1073
-
Comparative genomic and phylogenetic analysis of short-chain dehydrogenases/reductases with dual retinol/sterol substrate
specificity
Olga V. Belyaeva and Natalia Y. Kedishvili
Genomics
(2006)
88 :820
-
Low-dose SKA Progesterone and Interleukin-10 modulate the inflammatory pathway in endometriotic cell lines
Francesca Mancini, Domenico Milardi, Piero Carfagna, Giuseppe Grande, Vincenzo Miranda, Alessandra De Cicco Nardone, Domenico
Ricciardi, Alfredo Pontecorvi, Riccardo Marana, and Fiorenzo De Cicco Nardone
International Immunopharmacology
(2018)
55 :223
-
New frontiers in androgen biosynthesis and metabolism
Trevor M Penning
Current Opinion in Endocrinology, Diabetes and Obesity
(2010)
17 :233
-
Estrone and estradiol C-16 derivatives as inhibitors of type 1 17β-hydroxysteroid dehydrogenase
Donald Poirier, Ho-Jin Chang, Arezki Azzi, Roch P. Boivin, and Sheng-Xiang Lin
Molecular and Cellular Endocrinology
(2006)
248 :236