-
Phytoestrogens as inhibitors of the human progesterone metabolizing enzyme AKR1C1
Petra Brožič, Tina Šmuc, Stanislav Gobec, and Tea Lanišnik Rižner
Molecular and Cellular Endocrinology
(2006)
259 :30
-
Isolation and characterization of the murine prostate short-chain dehydrogenase/reductase 1 (Psdr1) gene, a new member of
the short-chain steroid dehydrogenase/reductase family
Stacy Moore, Colin Pritchard, Biaoyang Lin, Camari Ferguson, and Peter S. Nelson
Gene
(2002)
293 :149
-
Multiplicity of Mammalian Reductases for Xenobiotic Carbonyl Compounds
Toshiyuki Matsunaga, Shinichi Shintani, and Akira Hara
Drug Metabolism and Pharmacokinetics
(2006)
21 :1
-
Hydroxysteroid dehydrogenases: ancient and modern regulators of adrenal and sex steroid action
Michael E. Baker
Molecular and Cellular Endocrinology
(2001)
175 :1
-
The correlation between the response to progestogen treatment and the expression of progesterone receptor B and 17β-hydroxysteroid
dehydrogenase type 2 in human endometrial carcinoma
Hiroki Utsunomiya, Takashi Suzuki, Kiyoshi Ito, Takuya Moriya, Ryo Konno, Shinji Sato, Nobuo Yaegashi, Kunihiro Okamura, and
Hironobu Sasano
Clinical Endocrinology
(2003)
58 :696
-
Human type 10 17β-hydroxysteroid dehydrogenase: molecular modelling and substrate docking
Erik Nordling, Udo C.T. Oppermann, Hans Jörnvall, and Bengt Persson
Journal of Molecular Graphics and Modelling
(2001)
19 :514
-
The diversity of sex steroid action: novel functions of hydroxysteroid (17 ) dehydrogenases as revealed by genetically modified
mouse models
T. Saloniemi, H. Jokela, L. Strauss, P. Pakarinen, and M. Poutanen
Journal of Endocrinology
(2012)
212 :27
-
Localization of type 5 17β-hydroxysteroid dehydrogenase mRNA in mouse tissues as studied by in situ hybridization
G. Pelletier, V. Luu-The, S. Li, and F. Labrie
Cell and Tissue Research
(2005)
320 :393
-
Inhibitory effects of fluorine-substituted estrogens on the activity of 17beta-hydroxysteroid dehydrogenases
Dominga Deluca, Gabriele Möller, Andrea Rosinus, Walter Elger, Alexander Hillisch, and Jerzy Adamski
Molecular and Cellular Endocrinology
(2006)
248 :218
-
Evolution of 17β-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action
Michael E Baker
Molecular and Cellular Endocrinology
(2001)
171 :211
-
Type 10 17beta-hydroxysteroid dehydrogenase catalyzing the oxidation of steroid modulators of γ-aminobutyric acid type A receptors
Xue-Ying He, Jerzy Wegiel, Ying-Zi Yang, Raju Pullarkat, Horst Schulz, and Song-Yu Yang
Molecular and Cellular Endocrinology
(2005)
229 :111
-
Derivatives of pyrimidine, phthalimide and anthranilic acid as inhibitors of human hydroxysteroid dehydrogenase AKR1C1
P. Brožič, J. Cesar, A. Kovač, M. Davies, A.P. Johnson, C.W.G. Fishwick, T. Lanišnik Rižner, and S. Gobec
Chemico-Biological Interactions
(2009)
178 :158
-
Structure and function of 17β-hydroxysteroid dehydrogenase type 1 and type 2
P Vihko, V Isomaa, and D Ghosh
Molecular and Cellular Endocrinology
(2001)
171 :71
-
Steroid hormone production by parasites: the case of Taenia crassiceps and Taenia solium cysticerci
M.C. Romano, R.A. Valdéz, A.L. Cartas, Y. Gómez, and C. Larralde
The Journal of Steroid Biochemistry and Molecular Biology
(2003)
85 :221
-
Metabolic conversion as a pre-receptor control mechanism for lipophilic hormones
Stefan Nobel, Lars Abrahmsen, and Udo Oppermann
European Journal of Biochemistry
(2001)
268 :4113
-
In vitro metabolism of dehydroepiandrosterone (DHEA) to 7α-hydroxy-DHEA and Δ5-androstene-3β,17β-diol in specific regions
of the aging brain from Alzheimer’s and non-demented patients
Sébastien Weill-Engerer, Jean-Philippe David, Véronique Sazdovitch, Philippe Liere, Michael Schumacher, André Delacourte,
Etienne-Emile Baulieu, and Yvette Akwa
Brain Research
(2003)
969 :117
-
Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17β-hydroxysteroid dehydrogenase
Type 3
Joanna M. Day, Helena J. Tutill, Paul A. Foster, Helen V. Bailey, Wesley B. Heaton, Christopher M. Sharland, Nigel Vicker,
Barry V.L. Potter, Atul Purohit, and Michael J. Reed
Molecular and Cellular Endocrinology
(2009)
301 :251
-
Expression of Enzymes Involved in Estrogen Metabolism in Human Prostate
Yasukazu Takase, Marie-Hélène Lévesque, Van Luu-The, Mohamed El-Alfy, Fernand Labrie, and Georges Pelletier
Journal of Histochemistry & Cytochemistry
(2006)
54 :911
-
Zebrafish 17beta-hydroxysteroid dehydrogenases: An evolutionary perspective
R. Mindnich and J. Adamski
Molecular and Cellular Endocrinology
(2009)
301 :20
-
Analysis and characteristics of multiple types of human 17β-hydroxysteroid dehydrogenase
Van Luu-The
The Journal of Steroid Biochemistry and Molecular Biology
(2001)
76 :143
-
EngineeringMycobacterium smegmatisfor testosterone production
Lorena Fernández-Cabezón, Beatriz Galán, and José L. García
Microbial Biotechnology
(2017)
10 :151
-
Cloning of 17β-Hydroxysteroid Dehydrogenase-I cDNAs from Japanese Eel Ovary
Yukinori Kazeto, Shigeho Ijiri, Hajime Matsubara, Shinji Adachi, and Kohei Yamauchi
Biochemical and Biophysical Research Communications
(2000)
279 :451
-
Aromatase in the brain of teleost fish: Expression, regulation and putative functions
Nicolas Diotel, Yann Le Page, Karen Mouriec, Sok-Keng Tong, Elisabeth Pellegrini, Colette Vaillant, Isabelle Anglade, François
Brion, Farzad Pakdel, Bon-chu Chung, and Olivier Kah
Frontiers in Neuroendocrinology
(2010)
31 :172
-
Type 5 17β-hydroxysteroid dehydrogenase: its role in the formation of androgens in women
Van Luu-The, Isabelle Dufort, Georges Pelletier, and Fernand Labrie
Molecular and Cellular Endocrinology
(2001)
171 :77
-
Effect of nomegestrol acetate on estrogen biosynthesis and transformation in MCF-7 and T47-D breast cancer cells
J. Shields-Botella, G. Chetrite, S. Meschi, and J.R. Pasqualini
The Journal of Steroid Biochemistry and Molecular Biology
(2005)
93 :1
-
Re-evaluating the Significance of Estrone as an Environmental Estrogen
Gerald T. Ankley, David Feifarek, Brett Blackwell, Jenna E. Cavallin, Kathleen M. Jensen, Michael D. Kahl, Shane Poole, Eric
Randolph, Travis Saari, and Daniel L. Villeneuve
Environmental Science & Technology
(2017)
51 :4705
-
Cloning, characterization and functional expression of Taenia solium 17 beta-hydroxysteroid dehydrogenase
A. Aceves-Ramos, P. de la Torre, L. Hinojosa, A. Ponce, R. García-Villegas, J.P. Laclette, R.J. Bobes, and M.C. Romano
General and Comparative Endocrinology
(2014)
203 :186
-
A guide to 17β-hydroxysteroid dehydrogenases
Jerzy Adamski and Franz J Jakob
Molecular and Cellular Endocrinology
(2001)
171 :1
-
AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer
Tea Lanišnik Rižner, Tina Šmuc, Ruth Rupreht, Jasna Šinkovec, and Trevor M. Penning
Molecular and Cellular Endocrinology
(2006)
248 :126
-
Functional aspects of 17beta-hydroxysteroid dehydrogenase 1 determined by comparison to a closely related retinol dehydrogenase
R. Mindnich and J. Adamski
The Journal of Steroid Biochemistry and Molecular Biology
(2007)
104 :334
-
Androsterone 3β-substituted derivatives as inhibitors of type 3 17β-hydroxysteroid dehydrogenase
Béatrice Tchédam Ngatcha, Van Luu-The, and Donald Poirier
Bioorganic & Medicinal Chemistry Letters
(2000)
10 :2533
-
Sex Determination and Differentiation
David T. MacLaughlin and Patricia K. Donahoe
New England Journal of Medicine
(2004)
350 :367
-
STX2171, a 17 -hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate
cancer model
J. M. Day, P. A. Foster, H. J. Tutill, F. Schmidlin, C. M. Sharland, J. D. Hargrave, N. Vicker, B. V. L. Potter, M. J. Reed,
and A. Purohit
Endocrine Related Cancer
(2013)
20 :53
-
Neurosteroid Biosynthesis in the Human Brain and Its Clinical Implications
BIRGIT STOFFEL-WAGNER
Annals of the New York Academy of Sciences
(2003)
1007 :64
-
Characterization of the dehydroepiandrosterone (DHEA) metabolism via oxysterol 7α-hydroxylase and 17-ketosteroid reductase
activity in the human brain
Stephan Steckelbroeck, Matthias Watzka, Dieter Lütjohann, Paul Makiola, Alexander Nassen, Volkmar H. J. Hans, Hans Clusmann,
Annette Reissinger, Michael Ludwig, Lothar Siekmann, and Dietrich Klingmüller
Journal of Neurochemistry
(2002)
83 :713
-
Molecular mechanisms of estrogen recognition and 17-keto reduction by human 17β-hydroxysteroid dehydrogenase 1
Debashis Ghosh and Pirkko Vihko
Chemico-Biological Interactions
(2001)
130-132 :637
-
Weight loss significantly reduces serum lipocalin-2 levels in overweight and obese women with polycystic ovary syndrome
Ekaterini Koiou, Konstantinos Tziomalos, Ilias Katsikis, Eleni A. Kandaraki, Emmanuil Kalaitzakis, Dimitrios Delkos, Christos
Vosnakis, and Dimitrios Panidis
Gynecological Endocrinology
(2012)
28 :20
-
Chemical synthesis of 16β-propylaminoacyl derivatives of estradiol and their inhibitory potency on type 1 17β-hydroxysteroid
dehydrogenase and binding affinity on steroid receptors
Martin R. Tremblay, Sheng-Xiang Lin, and Donald Poirier
Steroids
(2001)
66 :821
-
Progestins used in endocrine therapy and the implications for the biosynthesis and metabolism of endogenous steroid hormones
Renate Louw-du Toit, Karl-Heinz Storbeck, Meghan Cartwright, Angelique Cabral, and Donita Africander
Molecular and Cellular Endocrinology
(2017)
441 :31
-
Cinnamic acid esters as potent inhibitors of fungal 17β-hydroxysteroid dehydrogenase––a model enzyme of the short-chain dehydrogenase/reductase
superfamily
Stanislav Gobec, Matej Sova, Katja Kristan, and Tea Lanišnik Rižner
Bioorganic & Medicinal Chemistry Letters
(2004)
14 :3933
-
Evolutionary analysis of 11β-hydroxysteroid dehydrogenase-type 1, -type 2, -type 3 and 17β-hydroxysteroid dehydrogenase-type
2 in fish
Michael E. Baker
FEBS Letters
(2004)
574 :167
-
3β-Alkyl-androsterones as inhibitors of type 3 17β-hydroxysteroid dehydrogenase: Inhibitory potency in intact cells, selectivity
towards isoforms 1, 2, 5 and 7, binding affinity for steroid receptors, and proliferative/antiproliferative activities on
AR+ and ER+ cell lines
Béatrice Tchédam Ngatcha, Yannick Laplante, Fernand Labrie, Van Luu-The, and Donald Poirier
Molecular and Cellular Endocrinology
(2006)
248 :225
-
In vitro and in vivo evaluation of a 3β-androsterone derivative as inhibitor of 17β-hydroxysteroid dehydrogenase type 3
Jenny Roy, Michelle-Audrey Fournier, René Maltais, Lucie Carolle Kenmogne, and Donald Poirier
The Journal of Steroid Biochemistry and Molecular Biology
(2014)
141 :44
-
Selective conversion by microglia of dehydroepiandrosterone to 5-androstenediol—A steroid with inherent estrogenic properties
Peter H. Jellinck, Martin Kaufmann, Andres Gottfried-Blackmore, Bruce S. McEwen, Glenville Jones, and Karen Bulloch
The Journal of Steroid Biochemistry and Molecular Biology
(2007)
107 :156
-
In vivo mouse model for analysis of hydroxysteroid (17β) dehydrogenase 1 inhibitors
Tarja Lamminen, Taija Saloniemi, Kaisa Huhtinen, Pasi Koskimies, Josef Messinger, Bettina Husen, Hubert Thole, and Matti Poutanen
Molecular and Cellular Endocrinology
(2009)
301 :158
-
HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer
Krishan K. Rasiah, Margaret Gardiner-Garden, Emma J.D. Padilla, Gabriele Möller, James G. Kench, M. Chehani Alles, Sarah A.
Eggleton, Phillip D. Stricker, Jerzy Adamski, Robert L. Sutherland, Susan M. Henshall, and Vanessa M. Hayes
Molecular and Cellular Endocrinology
(2009)
301 :89
-
Searching for the physiological function of 17β-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: studies
of substrate specificity and expression analysis
T Lanišnik Rižner, J Stojan, and J Adamski
Molecular and Cellular Endocrinology
(2001)
171 :193
-
Localization of Type 8 17β-hydroxysteroid Dehydrogenase mRNA in Mouse Tissues as Studied by In Situ Hybridization
Georges Pelletier, Van Luu-The, Songyun Li, and Fernand Labrie
Journal of Histochemistry & Cytochemistry
(2005)
53 :1257
-
Molecular and functional evolution of human DHRS2 and DHRS4 duplicated genes
Franco Gabrielli and Sergio Tofanelli
Gene
(2012)
511 :461
-
Bioactive withanolides from Withania obtusifolia
Feras Q. Alali, Chiraz Soumia M. Amrine, Tamam El-Elimat, Ahmad Alkofahi, Khaled Tawaha, Mohammad Gharaibah, Steven M. Swanson,
Joseph O. Falkinham, Marisa Cabeza, Araceli Sánchez, Mario Figueroa, and Nicholas H. Oberlies
Phytochemistry Letters
(2014)
9 :96
-
The impact of testosterone, tibolone and black cohosh on purified mammary and placental 17β-hydroxysteroid dehydrogenase type
1
Petra Stute, Kathrin Kalkhake, Ludwig Kiesel, and Martin Götte
Journal of Enzyme Inhibition and Medicinal Chemistry
(2015)
30 :448
-
Downregulation of estrogen-metabolizing 17β-hydroxysteroid dehydrogenase Type 2 expression correlates inversely with Ki67
proliferation marker in colon-cancer development
Olayiwola O. Oduwole, Veli V. Isomaa, Pasi A. Nokelainen, Frej Stenbäck, and Pirkko T. Vihko
International Journal of Cancer
(2002)
97 :1
-
A human short-chain dehydrogenase/reductase gene: structure, chromosomal localization, tissue expression and subcellular localization
of its product
Silvia Pellegrini, Stefano Censini, Silvia Guidotti, Paola Iacopetti, Mariano Rocchi, Marco Bianchi, Antonello Covacci, and
Franco Gabrielli
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
(2002)
1574 :215
-
17β-Hydroxysteroid dehydrogenase inhibitors: a patent review
Donald Poirier
Expert Opinion on Therapeutic Patents
(2010)
20 :1123
-
Sex steroids and parasitism: Taenia crassiceps cisticercus metabolizes exogenous androstenedione to testosterone in vitro
Y Gomez, R.A Valdez, C Larralde, and M.C Romano
The Journal of Steroid Biochemistry and Molecular Biology
(2000)
74 :143
-
17β-Hydroxysteroid dehydrogenases involved in local oestrogen synthesis have prognostic significance in breast cancer
C Gunnarsson, E Hellqvist, and O Stål
British Journal of Cancer
(2005)
92 :547
-
17β-Hydroxysteroid Dehydrogenase from Cochliobolus lunatus: Model Structure and Substrate Specificity
Tea Lanišnik Rižner, Jerzy Adamski, and Jure Stojan
Archives of Biochemistry and Biophysics
(2000)
384 :255
-
Molecular Cloning of a Novel Type of Rat Cytoplasmic 17β-Hydroxysteroid Dehydrogenase Distinct from the Type 5 Isozyme
Shuhei Ishikura, Kengo Matsumoto, Masaharu Sanai, Kenji Horie, Toshiyuki Matsunaga, Kazuo Tajima, Ossama El-Kabbani, and Akira
Hara
The Journal of Biochemistry
(2006)
139 :1053
-
Multifunctionality of human 17β-hydroxysteroid dehydrogenases
Gabriele Moeller and Jerzy Adamski
Molecular and Cellular Endocrinology
(2006)
248 :47
-
Structural basis of the multispecificity demonstrated by 17β-hydroxysteroid dehydrogenase types 1 and 5
S.-X. Lin, R. Shi, W. Qiu, A. Azzi, D.-W. Zhu, H. Al Dabbagh, and M. Zhou
Molecular and Cellular Endocrinology
(2006)
248 :38
-
Transcriptional regulation of the human type 8 17β-hydroxysteroid dehydrogenase gene by C/EBPβ
Joaquín Villar, Jon Celay, Marta M. Alonso, Mirja Rotinen, Carlos de Miguel, Marco Migliaccio, and Ignacio Encío
The Journal of Steroid Biochemistry and Molecular Biology
(2007)
105 :131
-
Production, purification, and functional analysis of recombinant human and mouse 17β-hydroxysteroid dehydrogenase type 7
Svea Törn, Pasi Nokelainen, Riitta Kurkela, Anitta Pulkka, Marta Menjivar, Sikha Ghosh, Miguel Coca-Prados, Hellevi Peltoketo,
Veli Isomaa, and Pirkko Vihko
Biochemical and Biophysical Research Communications
(2003)
305 :37
-
Obesity, weight loss, and the polycystic ovary syndrome: effect of treatment with diet and orlistat for 24 weeks on insulin
resistance and androgen levels
Dimitrios Panidis, Dimitrios Farmakiotis, David Rousso, Anargyros Kourtis, Ilias Katsikis, and Gerassimos Krassas
Fertility and Sterility
(2008)
89 :899
-
Association of Genetic Polymorphisms in HSD17B1, HSD17B2 and SHBG Genes with Hepatocellular Carcinoma Risk
Lu Shun Zhang, Fang Yuan, Xuan Guan, Juan Li, Xin Lian Liu, Jing Sun, Bo Liu, Wei Ma, and Feng Mei Deng
Pathology & Oncology Research
(2014)
20 :661
-
17β-Hydroxysteroid dehydrogenase (17β-HSD) in scleractinian corals and zooxanthellae
Charles H. Blomquist, P.H. Lima, A.M. Tarrant, M.J. Atkinson, and S. Atkinson
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
(2006)
143 :397
-
Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses
Nan-Shan Chang, Joan Doherty, Amy Ensign, Jennifer Lewis, John Heath, Lori Schultz, Shur-Tzu Chen, and Udo Oppermann
Biochemical Pharmacology
(2003)
66 :1347
-
Expression of the 17β-hydroxysteroid dehydrogenase type 5 mRNA in the human brain
Stephan Steckelbroeck, Matthias Watzka, Birgit Stoffel-Wagner, Volkmar H.J Hans, Lioba Redel, Hans Clusmann, Christian E Elger,
Frank Bidlingmaier, and Dietrich Klingmüller
Molecular and Cellular Endocrinology
(2001)
171 :165
-
Estrogen-producing steroidogenic pathways in parietal cells of the rat gastric mucosa
Takashi Ueyama, Nobuyuki Shirasawa, Takao Ito, and Yoshihiro Tsuruo
Life Sciences
(2004)
74 :2327
-
Polymorphisms in genes hydroxysteroid-dehydrogenase-17b type 2 and type 4 and endometrial cancer risk
Stalo Karageorgi, Monica McGrath, I-Min Lee, Julie Buring, Peter Kraft, and Immaculata De Vivo
Gynecologic Oncology
(2011)
121 :54
-
Deletion of 12 carboxyl-terminal residues from pig 3α/β,20β-hydroxysteroid dehydrogenase affects steroid metabolism
Shizuo Nakajin, Masaya Itoda, Shuji Ohno, Noriko Takase, Satoshi Toyoshima, and Michael E Baker
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
(2001)
1550 :175
-
Mechanisms of estradiol inactivation in primate endometrium
Bettina Husen, Jerzy Adamski, Gabriele M Rune, and Almuth Einspanier
Molecular and Cellular Endocrinology
(2001)
171 :179
-
Estrogen synthesis and secretion during postnatal testicular development in male goats: In situ aromatase mRNA expression
L. Ortiz-Carrera, R.A. Valdez, J.A. Mondragón, P. Gariglio, L. Zarco, J. Valencia, and M.C. Romano
Small Ruminant Research
(2015)
130 :146
-
Identification and characterization of 17β-hydroxysteroid dehydrogenases in the zebrafish, Danio rerio
R Mindnich, D Deluca, and J Adamski
Molecular and Cellular Endocrinology
(2004)
215 :19
-
Characterization of the oestrogenic activity of non-aromatic steroids: are there male-specific endogenous oestrogen receptor
modulators?
Pan Wang, Yujing Wen, Gui-Zhen Han, Pritam Kaur Sidhu, and Bao Ting Zhu
British Journal of Pharmacology
(2009)
158 :1796
-
Factors that Mediate and Modulate Androgen Action
M.J. McPhaul
Journal of Investigative Dermatology Symposium Proceedings
(2003)
8 :1
-
17β-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer
Joanna M. Day, Paul A. Foster, Helena J. Tutill, Michael F.C. Parsons, Simon P. Newman, Surinder K. Chander, Gillian M. Allan,
Harshani R. Lawrence, Nigel Vicker, Barry V.L. Potter, Michael J. Reed, and Atul Purohit
International Journal of Cancer
(2008)
122 :1931
-
Chemical Synthesis of (S)-Spiro(estradiol-17,2′-[1,4]oxazinan)-6′-one Derivatives Bearing Two Levels of Molecular Diversity
François Rouillard, Jenny Roy, and Donald Poirier
European Journal of Organic Chemistry
(2008)
2008 :2446
-
Evolution of Retinoid and Steroid Signaling: Vertebrate Diversification from an Amphioxus Perspective
R. Albalat, F. Brunet, V. Laudet, and M. Schubert
Genome Biology and Evolution
(2011)
3 :985
-
Characterization of Two Isoforms of Mouse 3(17)α-Hydroxysteroid Dehydrogenases of the Aldo-Keto Reductase Family
Syuhei Ishikura, Noriyuki Usami, Satoko Nakajima, Akiko Kameyama, Hiroaki Shiraishi, Vincenzo Carbone, Ossama El-Kabbani,
and Akira Hara
Biological & Pharmaceutical Bulletin
(2004)
27 :1939
-
Immunohistochemical analysis of 17β-hydroxysteroid dehydrogenase isozymes in human ovarian surface epithelium and epithelial
ovarian carcinoma
Ken-ichi Motohara, Hironori Tashiro, Yumiko Taura, Takashi Ohba, and Hidetaka Katabuchi
Medical Molecular Morphology
(2010)
43 :197
-
Steroid Hormones and the Development of Reproductive Organs
K. Morohashi, T. Baba, and M. Tanaka
Sexual Development
(2013)
7 :61
-
11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role
in castration resistant prostate cancer?
Karl-Heinz Storbeck, Liezl M. Bloem, Donita Africander, Lindie Schloms, Pieter Swart, and Amanda C. Swart
Molecular and Cellular Endocrinology
(2013)
377 :135
-
HSD17B1 expression enhances estrogen signaling stimulated by the low active estrone, evidenced by an estrogen responsive element-driven
reporter gene in vivo
Päivi Järvensivu, Taija Saloniemi-Heinonen, Michael Awosanya, Pasi Koskimies, Niina Saarinen, and Matti Poutanen
Chemico-Biological Interactions
(2015)
234 :126
-
Focused Libraries of 16-Substituted Estrone Derivatives and Modified E-Ring Steroids: Inhibitors of 17ß-Hydroxysteroid Dehydrogenase
Type 1
Nigel Vicker, Harshani R. Lawrence, Gillian M. Allan, Christian Bubert, Andrew Smith, Helena J. Tutill, Atul Purohit, Joanna M.
Day, Mary F. Mahon, Michael J. Reed, and Barry V. L. Potter
ChemMedChem
(2006)
1 :464
-
Distribution of 17β-hydroxysteroid dehydrogenases in human osteoblast-like cells
Maritta Feix, Lutz Wolf, and Hans-Udo Schweikert
Molecular and Cellular Endocrinology
(2001)
171 :163
-
Polymorphisms in genes HSD17B1 and HSD17B2 and uterine leiomyoma risk in Chinese women
Rui-Juan Cong, Zhong-Ying Huang, Ling Cong, Yi Ye, Zheng Wang, Lagabaiyila Zha, Li-Ping Cao, Xiao-Wei Su, Jing Yan, and Ying-Bi
Li
Archives of Gynecology and Obstetrics
(2012)
286 :701
-
Aldo-keto Reductase 1B15 (AKR1B15)
Susanne Weber, Joshua K. Salabei, Gabriele Möller, Elisabeth Kremmer, Aruni Bhatnagar, Jerzy Adamski, and Oleg A. Barski
Journal of Biological Chemistry
(2015)
290 :6531
-
The Contribution of 17beta-Hydroxysteroid Dehydrogenase Type 1 to the Estradiol-Estrone Ratio in Estrogen-Sensitive Breast
Cancer Cells
Chen-Yan Zhang, Jiong Chen, Da-Chuan Yin, Sheng-Xiang Lin, and Susan Kovats
PLoS ONE
(2012)
7 :e29835
-
Reductive 17β-hydroxysteroid dehydrogenases in the sulfatase pathway: Critical in the cell proliferation of breast cancer
Juliette A. Aka, Mausumi Mazumdar, and Sheng-Xiang Lin
Molecular and Cellular Endocrinology
(2009)
301 :183
-
Inhibition of type 2 17β-hydroxysteroid dehydrogenase by estradiol derivatives bearing a lactone on the D-ring: structure–activity
relationships
Patrick Bydal, Serge Auger, and Donald Poirier
Steroids
(2004)
69 :325
-
SDR-type human hydroxysteroid dehydrogenases involved in steroid hormone activation
Xiaoqiu Wu, Petra Lukacik, Kathryn L. Kavanagh, and Udo Oppermann
Molecular and Cellular Endocrinology
(2007)
265-266 :71
-
Evaluation of urinary excretion of androgens conjugated to cysteine in human pregnancy by mass spectrometry
Andreu Fabregat, Josep Marcos, Lorena Garrostas, Jordi Segura, Oscar J. Pozo, and Rosa Ventura
The Journal of Steroid Biochemistry and Molecular Biology
(2014)
139 :192
-
Determination of cDNA, gene structure and chromosomal localization of the novel human 17β-hydroxysteroid dehydrogenase type
7
Antje Krazeisen, Rainer Breitling, Kenji Imai, Stephanie Fritz, Gabriele Möller, and Jerzy Adamski
FEBS Letters
(1999)
460 :373
-
Localization of type 7 17β-hydroxysteroid dehydrogenase in mouse tissues
G. Pelletier, V. Luu-The, S. Li, and F. Labrie
The Journal of Steroid Biochemistry and Molecular Biology
(2005)
93 :49
-
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase
yielding 11β-hydroxy-5α-androstanedione
Amanda C. Swart, Lindie Schloms, Karl-Heinz Storbeck, Liezl M. Bloem, Therina du Toit, Jonathan L. Quanson, William E. Rainey,
and Pieter Swart
The Journal of Steroid Biochemistry and Molecular Biology
(2013)
138 :132
-
Characterisation of estrogenic 17β-hydroxysteroid dehydrogenase (17β-HSD) activity in the human brain
Stephan Steckelbroeck, Matthias Watzka, Annette Reissinger, Petra Wegener-Toper, Frank Bidlingmaier, Niklaas Bliesener, Volkmar
H.J. Hans, Hans Clusmann, Michael Ludwig, Lothar Siekmann, and Dietrich Klingmüller
The Journal of Steroid Biochemistry and Molecular Biology
(2003)
86 :79
-
Characterization of 17β-Hydroxysteroid Dehydrogenase Type 7 in Reproductive Tissues of the Marmoset Monkey1
B. Husen, J. Adamski, A. Brüns, D. Deluca, K. Fuhrmann, G. Möller, I. Schwabe, and A. Einspanier
Biology of Reproduction
(2003)
68 :2092
-
Production of androstenones from phytosterol by mutants of Mycobacterium sp.
Chen-Lang Huang, Yen-Rong Chen, and Wen-Hsiung Liu
Enzyme and Microbial Technology
(2006)
39 :296
-
Molecular basis of d-bifunctional protein deficiency
G Möller, E.G van Grunsven, R.J.A Wanders, and J Adamski
Molecular and Cellular Endocrinology
(2001)
171 :61
-
Expression of Estrogen Receptor β in Colon Cancer Progression
Francesca Castiglione, Antonio Taddei, Duccio Rossi DeglʼInnocenti, Anna Maria Buccoliero, Paolo Bechi, Francesca Garbini,
Francesca Gheri Chiara, Daniela Moncini, Giulia Cavallina, Lavinia Marascio, Giancarlo Freschi, and Luigi Taddei Gian
Diagnostic Molecular Pathology
(2008)
17 :231
-
Metabolic changes in Medaka fish induced by cyanobacterial exposures in mesocosms: an integrative approach combining proteomic
and metabolomic analyses
Benoît Sotton, Alain Paris, Séverine Le Manach, Alain Blond, Gérard Lacroix, Alexis Millot, Charlotte Duval, Hélène Huet,
Qin Qiao, Sophie Labrut, Giovanni Chiapetta, Joelle Vinh, Arnaud Catherine, and Benjamin Marie
Scientific Reports
(2017)
7 :
-
Intracrine Control of Estrogen Action in Human Gestational Tissues at Parturition
Gemma Madsen, Tamas Zakar, Ursula Manuelpillai, Euan Wallace, Kenneth Kwek, George S. H. Yeo, Roger Smith, and Sam Mesiano
Journal of the Society for Gynecologic Investigation
(2004)
11 :213
-
Dithioerythritol (DTE) prevents inhibitory effects of triphenyltin (TPT) on the key enzymes of the human sex steroid hormone
metabolism
Susan Lo, Axel Alléra, Peter Albers, Jörg Heimbrecht, Eckard Jantzen, Dietrich Klingmüller, and Stephan Steckelbroeck
The Journal of Steroid Biochemistry and Molecular Biology
(2003)
84 :569
-
Androgenic and estrogenic 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase in human ovarian epithelial tumors: evidence
for the type 1, 2 and 5 isoforms
Charles H Blomquist, Martin Bonenfant, Dennis M McGinley, Zoltan Posalaky, David J Lakatua, Sarah Tuli-Puri, Dennis G Bealka,
and Yves Tremblay
The Journal of Steroid Biochemistry and Molecular Biology
(2002)
81 :343
-
Crucial role of cytokines in sex steroid formation in normal and tumoral tissues
Jacques Simard and Sebastien Gingras
Molecular and Cellular Endocrinology
(2001)
171 :25
-
The prognostic impact of lipid biosynthesis-associated markers, HSD17B2 and HMGCS2, in rectal cancer treated with neoadjuvant
concurrent chemoradiotherapy
Ying-En Lee, Hong-Lin He, Yow-Ling Shiue, Sung-Wei Lee, Li-Ching Lin, Ting-Feng Wu, I-Wei Chang, Hao-Hsien Lee, and Chien-Feng
Li
Tumor Biology
(2015)
36 :7675
-
Inhibitors of type II 17β-hydroxysteroid dehydrogenase
Donald Poirier, Patrick Bydal, Martin R Tremblay, Kay-Mane Sam, and Van Luu-The
Molecular and Cellular Endocrinology
(2001)
171 :119
-
Inhibitors of steroidogenesis as agents for the treatment of hormone-dependent cancers
H John Smith, Paul J Nicholls, Claire Simons, and Regis Le Lain
Expert Opinion on Therapeutic Patents
(2001)
11 :789
-
Reprint of “In vitro and in vivo evaluation of a 3β-androsterone derivative as inhibitor of 17β-hydroxysteroid dehydrogenase
type 3”
Jenny Roy, Michelle-Audrey Fournier, René Maltais, Lucie Carolle Kenmogne, and Donald Poirier
The Journal of Steroid Biochemistry and Molecular Biology
(2015)
153 :170
-
Rational proteomics IV: modeling the primary function of the mammalian 17β-hydroxysteroid dehydrogenase type 8
Vladimir Z. Pletnev and William L. Duax
The Journal of Steroid Biochemistry and Molecular Biology
(2005)
94 :327
-
Human HSD17B1 expression masculinizes transgenic female mice
Taija Saloniemi, Michelle Welsh, Tarja Lamminen, Philippa Saunders, Sari Mäkelä, Tomi Streng, and Matti Poutanen
Molecular and Cellular Endocrinology
(2009)
301 :163
-
Biochemical and biological evaluation of novel potent coumarin inhibitor of 17β-HSD type 1
Š. Starčević, P. Kocbek, G. Hribar, T. Lanišnik Rižner, and S. Gobec
Chemico-Biological Interactions
(2011)
191 :60
-
Cellular and Animal Studies: Insights into Pathophysiology and Therapy of PCOS
Inthrani Raja Indran, Bao Hui Lee, and Eu-Leong Yong
Best Practice & Research Clinical Obstetrics & Gynaecology
(2016)
37 :12
-
17β-Hydroxysteroid dehydrogenase-3 deficiency: A rare endocrine cause of male-to-female sex reversal
Silvano Bertelloni, M. Cristina Maggio, Giovanni Federico, Giampiero Baroncelli, and Olaf Hiort
Gynecological Endocrinology
(2006)
22 :488
-
Forms and functions of human SDR enzymes
Udo C.T. Oppermann, Charlotta Filling, and Hans Jörnvall
Chemico-Biological Interactions
(2001)
130-132 :699
-
Molecular cloning, modeling, and localization of rat type 10 17β-hydroxysteroid dehydrogenase1Nucleotide sequences of cDNAs
of rat and mouse type 10 17β-HSDs have been deposited in the GeneBank™/EBI Data Bank with accession number AF069770 and AF233685,
respectively.1
Xue-Ying He, George Merz, Chin-Hung Chu, Dawei Lin, Ying-Zi Yang, Pankaj Mehta, Horst Schulz, and Song-Yu Yang
Molecular and Cellular Endocrinology
(2001)
171 :89
-
Expression and regulation of 17β-hydroxysteroid dehydrogenase 7 in the rabbit
Claudia A Krusche, Gabriele Möller, Henning M Beier, and Jerzy Adamski
Molecular and Cellular Endocrinology
(2001)
171 :169
-
Diagnosis of 17β-hydroxysteroid dehydrogenase deficiency
Silvano Bertelloni, Eleonora Dati, and Olaf Hiort
Expert Review of Endocrinology & Metabolism
(2009)
4 :53
-
Males With 17β-Hydroxysteroid Dehydrogenase Deficiency
Jacques Simard, Anne Marie Moisan, Laurence Calemard Michel, and Yves Morel
The Endocrinologist
(2003)
13 :195
-
Identification and mRNA expression of two 17β-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis
following exposure to endocrine disrupting chemicals
Yingying Zhang, Qing Wang, Yinglu Ji, Qian Zhang, Huifeng Wu, Jia Xie, and Jianmin Zhao
Environmental Toxicology and Pharmacology
(2014)
37 :1243
-
Characterization and localization of human type10 17β-hydroxysteroid dehydrogenase
Xue-Ying He, George Merz, Ying-Zi Yang, Penkaj Mehta, Horst Schulz, and Song-Yu Yang
European Journal of Biochemistry
(2001)
268 :4899
-
Steroidogenic Enzyme and Key Decidualization Marker Dysregulation in Endometrial Stromal Cells from Women with Versus Without
Endometriosis1
L. Aghajanova, A. Hamilton, J. Kwintkiewicz, K.C. Vo, and L.C. Giudice
Biology of Reproduction
(2009)
80 :105
-
Evaluation of Human Interindividual Variation in Bioactivation of Estragole Using Physiologically Based Biokinetic Modeling
Ans Punt, Suzanne M. Jeurissen, Marelle G. Boersma, Thierry Delatour, Gabriele Scholz, Benoît Schilter, Peter J. van Bladeren,
and Ivonne M. C. M. Rietjens
Toxicological Sciences
(2010)
113 :337
-
Expression of 17β-hydroxysteroid dehydrogenases in mesophilic and extremophilic yeast
Tea Lanišnik Rižner, Jerzy Adamski, and Marija Žakelj–Mavrič
Steroids
(2001)
66 :49
-
Species Used for Drug Testing Reveal Different Inhibition Susceptibility for 17beta-Hydroxysteroid Dehydrogenase Type 1
Gabriele Möller, Bettina Husen, Dorota Kowalik, Leena Hirvelä, Dariusz Plewczynski, Leszek Rychlewski, Josef Messinger, Hubert
Thole, Jerzy Adamski, and Ulrich Zanger
PLoS ONE
(2010)
5 :e10969
-
Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases
Charlotta Filling, Xiaoqiu Wu, Naeem Shafqat, Malin Hult, Eva Mårtensson, Jawed Shafqat, and Udo C.T Oppermann
Molecular and Cellular Endocrinology
(2001)
171 :99
-
Corticosterone impairs the mRNA expression and activity of 3β- and 17β-hydroxysteroid dehydrogenases in adult rat Leydig cells
R. Badrinarayanan, S. Rengarajan, P. Nithya, and K. Balasubramanian
Biochemistry and Cell Biology
(2006)
84 :745
-
Steroid metabolism in cnidarians: Insights from Nematostella vectensis
Ann M. Tarrant, Adam M. Reitzel, Charles H. Blomquist, Ferdinand Haller, Janina Tokarz, and Jerzy Adamski
Molecular and Cellular Endocrinology
(2009)
301 :27
-
The “street light syndrome”, or how protein taxonomy can bias experimental manipulations
Gabriel Markov, Guillaume Lecointre, Barbara Demeneix, and Vincent Laudet
BioEssays
(2008)
30 :349
-
Expression in E. coli and tissue distribution of the human homologue of the mouse Ke 6 gene, 17β-hydroxysteroid dehydrogenase
type 8
Shuji Ohno, Kouki Nishikawa, Yoko Honda, and Shizuo Nakajin
Molecular and Cellular Biochemistry
(2008)
309 :209
-
17β-Hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female
patients with colon cancer
Olayiwola O. Oduwole, Markus J. Mäkinen, Veli V. Isomaa, Anitta Pulkka, Petra Jernvall, Tuomo J. Karttunen, and Pirkko T.
Vihko
The Journal of Steroid Biochemistry and Molecular Biology
(2003)
87 :133
-
Complexities of androgen action
Michael J. McPhaul and Maureen Young
Journal of the American Academy of Dermatology
(2001)
45 :S87
-
Characterization of fungal 17β-hydroxysteroid dehydrogenases
Tea Lanišnik Rižner and Marija Žakelj-Mavrič
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
(2000)
127 :53
-
Novel Hydroxysteroid (17β) Dehydrogenase 1 Inhibitors Reverse Estrogen-Induced Endometrial Hyperplasia in Transgenic Mice
Taija Saloniemi, Päivi Järvensivu, Pasi Koskimies, Heli Jokela, Tarja Lamminen, Sadaf Ghaem-Maghami, Roberto Dina, Pauliina
Damdimopoulou, Sari Mäkelä, Antti Perheentupa, Harry Kujari, Jan Brosens, and Matti Poutanen
The American Journal of Pathology
(2010)
176 :1443
-
17β-hydroxysteroid dehydrogenase from the fungus Cochlioboluslunatus: structural and functional aspects
T. Lanišnik Rižner, J. Stojan, and J. Adamski
Chemico-Biological Interactions
(2001)
130-132 :793
-
The role of 17 beta-hydroxysteroid dehydrogenases
R Mindnich, G Möller, and J Adamski
Molecular and Cellular Endocrinology
(2004)
218 :7
-
Parallel solid-phase synthesis of 3β-peptido-3α-hydroxy-5α-androstan-17-one derivatives for inhibition of type 3 17β-hydroxysteroid
dehydrogenase
René Maltais, Van Luu-The, and Donald Poirier
Bioorganic & Medicinal Chemistry
(2001)
9 :3101
-
Type 2 17-β hydroxysteroid dehydrogenase as a novel target for the treatment of osteoporosis
Jalal Soubhye, Ibaa Chikh Alard, Pierre van Antwerpen, and François Dufrasne
Future Medicinal Chemistry
(2015)
7 :1431
-
Expression of the estradiol-synthesizing 17ß-hydroxysteroid dehydrogenases type 1 and type 7 in the nonhuman primate Callithrix
jacchus
I Schwabe, B Husen, and A Einspanier
Molecular and Cellular Endocrinology
(2001)
171 :187
-
The importance of oestrogens in males
Willem de Ronde, Huibert A.P. Pols, Johannes P.T.M. van Leeuwen, and Frank H. de Jong
Clinical Endocrinology
(2003)
58 :529
-
Structure and function of human 17β-hydroxysteroid dehydrogenases
Petra Lukacik, Kathryn L. Kavanagh, and Udo Oppermann
Molecular and Cellular Endocrinology
(2006)
248 :61
-
Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid
17-beta-dehydrogenase-4 (HSD17B4)
Mykhaylo S. Frasinyuk, Wen Zhang, Przemyslaw Wyrebek, Tianxin Yu, Xuehe Xu, Vitaliy M. Sviripa, Svitlana P. Bondarenko, Yanqi
Xie, Huy X. Ngo, Andrew J. Morris, James L. Mohler, Michael V. Fiandalo, David S. Watt, and Chunming Liu
Org. Biomol. Chem.
(2017)
15 :7623
-
Co-evolution of steroidogenic and steroid-inactivating enzymes and adrenal and sex steroid receptors
Michael E. Baker
Molecular and Cellular Endocrinology
(2004)
215 :55
-
Modulation of estrogen synthesis and metabolism by phytoestrogens in vitro and the implications for women's health
Majorie B. M. van Duursen
Toxicol. Res.
(2017)
6 :772