Figure 1
Schematic representation of ER–mitochondria contact sites and the established cellular signaling. Several proteins implicated in mitochondria dynamics, Ca2+ signaling, cellular apoptosis or phospholipid exchange at MAM interface are depicted. In yellow mitochondria and in green the ER, the red arrows correspond to calcium flux. ER, endoplasmic reticulum; IMM, inner mitochondrial membrane; MAM, mitochondria-associated membranes; OMM, outer mitochondrial membrane.
