Figure 4
Models of ICI 164,384 and derivatives bound to ERβ. (A) ICI 164,384 (X = CH2, n = 9, R = C4H9); (B) a 13-atom side chain (X = S, n = 8, R = CH3); (C) a 15-atom side chain (X = S, n = 8, R = C3H7); (D) a 19-atom side chain (X = S, n = 8, R = C7H15); docking was performed using the Glide software as previously described (Hilmi et al. 2012).