Molecular phylogenetic tree of the ghrelin receptor (GHS-R1a) in mammals. The phylogenetic tree of amino acid (AA) sequences was constructed by using the neighbor-joining (NJ) method with MEGA4 Software (http://www.megasoftware.net/). The numbers on the branch points are the bootstrap values (as percentages based on 1000 replicates). AA sequences obtained from the Ensembl Genome Browser (http://www.ensembl.org/index.html). GeneID shows the following species name. Receptors for human motilin (MLNR), neuromedin-U (NMUR1), and neurotensin (NTSR1) were used as the out group. Symbols are defined as follows: closed circle, Euarchontoglires; open square, Afrotheria; asterisk, Marsupialia; open down triangle, Laurasiatheria.
- Thematic Review
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J Mol Endocrinol June 1, 2014 vol. 52 no. 3 T87-T100
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