(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2

Model of neuromedin U signaling in the regulation of bone formation. As a central regulator of a leptin-dependent regulation of bone mass, neuromedin U acts in the central nervous system downstream of leptin. Efferent sympathetic signaling through the sympathetic nervous system (SNS) affects the molecular clock in bone to regulate bone remodeling.

This Article

  1. J Mol Endocrinol vol. 45 no. 4 175-181