Searching journal content for articles similar to Severson and Zwart 24 (3): R27.

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  1. Review:
    • Takuma Uo,
    • Stephen R Plymate,
    • and Cynthia C Sprenger
    Allosteric alterations in the androgen receptor and activity in prostate cancer Endocr Relat Cancer 24 (9) R335-R348, doi:10.1530/ERC-17-0108
    ...number of genes. This concept holds true for the androgen receptor, which displays a diversity of inclusion/exclusion events in its structural motifs as a mechanism of resistance to the most forefront anti-androgen therapies. More than 20 androgen receptor variants that lack various portions of ligand...
  2. Thematic Review:
    • Elgene Lim,
    • Gerard Tarulli,
    • Neil Portman,
    • Theresa E Hickey,
    • Wayne D Tilley,
    • and Carlo Palmieri
    Pushing estrogen receptor around in breast cancer Endocr Relat Cancer 23 (12) T227-T241, doi:10.1530/ERC-16-0427 first published on 11 October 2016
    ...-promoting functions of ER. Introduction There are three major sex steroid hormones – estrogen, progesterone and androgen – and each affect the signalling activity of its cognate sex steroid receptor (SSR), that is the estrogen receptor-α (ER), progesterone receptor (PR) and androgen receptor (AR), respectively...
  3. Research:
    • Chun-Peng Liao,
    • Leng-Ying Chen,
    • Andrea Luethy,
    • Youngsoo Kim,
    • Kian Kani,
    • A Robert MacLeod,
    • and Mitchell E Gross
    Androgen receptor in cancer-associated fibroblasts influences stemness in cancer cells Endocr Relat Cancer 24 (4) 157-170, doi:10.1530/ERC-16-0138
    ...-specific clinical annotations were obtained from the cBio Cancer 160Research C-P Liao et al. Stromal androgen receptor and cancer stem cells DOI: 10.1530/ERC-16-0138 http://.endocrinology-journals.org © 2017 Society for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. 24:4 Genomes portal...
  4. Research:
    • Jaesung (Peter) Choi,
    • Reena Desai,
    • Yu Zheng,
    • Mu Yao,
    • Qihan Dong,
    • Geoff Watson,
    • David J Handelsman,
    • and Ulla Simanainen
    Androgen actions via androgen receptor promote PTEN inactivation induced uterine cancer Endocr Relat Cancer 22 (5) 687-701, doi:10.1530/ERC-15-0203
    ...demonstrated AR inactivation Key Words " androgens " androgen receptor " PTEN Introduction such as the uterus of women ) and rodents (Walters et al. e nuclear receptor superfamily mosomal gene (Quigley et al. ects of androgens in male Research J P Choi et al. AR-mediated androgen actions in uterine cancer 22...
  5. Review:
    • Alan P Lombard and
    • Maria Mudryj
    The emerging role of the androgen receptor in bladder cancer Endocr Relat Cancer 22 (5) R265-R277, doi:10.1530/ERC-15-0209 first published on 30 July 2015
    .... Review A P Lombard and M Mudryj Androgen receptor in bladder cancer 22 :5 R275bladder urothelial carcinoma: comprehensive analysis of 1,476 radical cystoprostatectomy specimens. Journal of Urology 190 1704–1709. (doi:10.1016/j.juro.2013.05.034) Cancer Genome Atlas Research Network 2014 Comprehensive...
  6. Review:
    • Elisabetta Pietri,
    • Vincenza Conteduca,
    • Daniele Andreis,
    • Ilaria Massa,
    • Elisabetta Melegari,
    • Samanta Sarti,
    • Lorenzo Cecconetto,
    • Alessio Schirone,
    • Sara Bravaccini,
    • Patrizia Serra,
    • Anna Fedeli,
    • Roberta Maltoni,
    • Dino Amadori,
    • Ugo De Giorgi,
    • and Andrea Rocca
    Androgen receptor signaling pathways as a target for breast cancer treatment Endocr Relat Cancer 23 (10) R485-R498, doi:10.1530/ERC-16-0190 first published on 15 August 2016
    ... J, Francis GD & Naderi A 2011 A feedback loop between androgen receptor and ERK signaling in estrogen receptor-negative breast cancer. Neoplasia 13 154–166. (doi:10.1593/neo.101324) Chia K, O’Brien M, Brown M & Lim E 2015 Targeting the androgen receptor in breast cancer. Current Oncology Reports 17 4. (doi...
  7. Thematic Review:
    • Keely M McNamara,
    • Nicole L Moore,
    • Theresa E Hickey,
    • Hironobu Sasano,
    • and Wayne D Tilley
    Complexities of androgen receptor signalling in breast cancer Endocr Relat Cancer 21 (4) T161-T181, doi:10.1530/ERC-14-0243 first published on 20 June 2014
    ...), the use of androgenin breast cancer is experienci contemporary pre-clinical stud utilising androgen receptor (AR therapies for women with meta current knowledge on the r in breast tumourigenesis will complexities of androgen actioappreciation of the role of androgen signalling pathways hormones...
  8. Thematic Review:
    • Damien A Leach,
    • Sue M Powell,
    • and Charlotte L Bevan
    WOMEN IN CANCER THEMATIC REVIEW: New roles for nuclear receptors in prostate cancer Endocr Relat Cancer 23 (11) T85-T108, doi:10.1530/ERC-16-0319 first published on 19 September 2016
    ...be tractable to activity modulation by small molecules. Moreover, genomic studies have shown that in models of CRPC, other nuclear receptors can potentially drive similar transcriptional responses to the androgen receptor, while analysis of expression and sequencing databases shows disproportionately high...
  9. Review:
    • Tracy Proverbs-Singh,
    • Jarett L Feldman,
    • Michael J Morris,
    • Karen A Autio,
    • and Tiffany A Traina
    Targeting the androgen receptor in prostate and breast cancer: several new agents in development Endocr Relat Cancer 22 (3) R87-R106, doi:10.1530/ERC-14-0543 first published on 26 February 2015
    ...orr ng C *(T Proverbs-Singh and J L Feldman are co-first authors) targeting this signaling pathway. Key Words " androgen receptor that includes the glucocorticoid, progesterone, and a highly conserved region, nger motif critical to DNA g domain (LBD) on the ponsible for the binding of androgens...
  10. Thematic Review:
    • Yulia Koryakina,
    • Huy Q Ta,
    • and Daniel Gioeli
    Androgen receptor phosphorylation: biological context and functional consequences Endocr Relat Cancer 21 (4) T131-T145, doi:10.1530/ERC-13-0472 first published on 14 January 2014
    ...Key Words " androgen receptor " cell signaling " gene transcription " growth factor " prostate (AF1)) that can function in the absence of ligand, a DNAthat involves interactions between the N- and C-termini; stellation of transcriptional factors, and components of chinery (Langley et al. 1995, 2001...
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