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  1. ...sinology, Diabetes and Metabolism, Correspondence to M Xing Key Words " TERT promoter mutation " thyroid cancer " telomerase reverse transcriptase " BRAF V600E mutation " genetic molecular markers " prognosis " diagnosis Telomerase reverse transcriptase (TERT) is the catalytic Telomerase is well...
  2. ...) Abstract Telomerase reverse transcriptase (TERT) promoter mutations C228T and C250T have recently been described in follicular cell-derived thyroid cancer (TC) in patients from North America and Europe. In this study, we explored whether these findings could be replicated in patients from a different...
  3. ...of thyroid cancer, and their possible clinical application is currently under evaluation. Particularly, mutations involving the promoter of the telomerase catalytic subunit telomerase reverse transcriptase (TERT) and the tumour suppressor TP53 are emerging as feasible tools for molecular prognostication...
  4. .... 2014).best studied is the BRAF V600E mutation. The presence of Published by Bioscientifica Ltd. the BRAF V600E mutation in papillary thyroid cancer was found to be associated with poor prognostic factors such as extrathyroidal invasion, lymph node metastases, and recurrence (reviewed in Xing (2007...
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