Searching journal content for telomerase reverse transcriptase (as phrase) in full text.

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Research:
- Trisha Dwight,
- Aidan Flynn,
- Kaushalya Amarasinghe,
- Diana E Benn,
- Richard Lupat,
- Jason Li,
- Daniel Cameron,
- Annette Hogg,
- Shiva Balachander,
- Ida Lm Candiloro,
- Stephen Wong,
- Bruce G Robinson,
- Anthony T Papenfuss,
- Anthony J Gill,
- Alexander Dobrovic,
- Rodney J Hicks,
- Roderick Clifton-Bligh,
- and Richard William Tothill
TERT structural rearrangements in metastatic pheochromocytomas Endocr Relat Cancer ERC-17-0306, doi:10.1530/ERC-17-0306 first published on 3 October 2017
...telomerase reverse transcriptase ~~~
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Review:
- Robert C. Mould,
- Jacob P. van Vloten,
- Amanda W. K. AuYeung,
- Khalil Karimi,
- and Byram W. Bridle
Immune response in the thyroid cancer microenvironment: making immunotherapy a possible mission Endocr Relat Cancer ERC-17-0316, doi:10.1530/ERC-17-0316 first published on 14 September 2017
...telomerase reverse transcriptase ~~~
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Review:
- Stephan Gasser,
- Lina H. K. Lim,
- and Florence S G Cheung
The role of the tumour microenvironment in immune therapy Endocr Relat Cancer ERC-17-0146, doi:10.1530/ERC-17-0146 first published on 28 July 2017
...telomerase reverse transcriptase (hTERT) to maintain telomere 507 ends of DNA(Maida and Masutomi 2015). The ability of hTERT peptides to induce 508 cancer cell-specific cytotoxic T cell activity was explored in the phase III TeloVac 509 study. The MHC class II telomerase vaccine GV1001 was given wit ~~~
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Research:
- Jan P Dumanski,
- Chiara Rasi,
- Peyman Björklund,
- Hanna Davies,
- Abir S Ali,
- Malin Grönberg,
- Staffan Welin,
- Halfdan Sorbye,
- Henning Grønbæk,
- Janet L Cunningham,
- Lars A Forsberg,
- Lars Lind,
- Erik Ingelsson,
- Peter Stålberg,
- Per Hellman,
- and Eva Tiensuu Janson
A MUTYH germline mutation is associated with small intestinal neuroendocrine tumors Endocr Relat Cancer 24 (8) 427-443, doi:10.1530/ERC-17-0196 first published on 20 June 2017
...telomerase reverse transcriptase gene (TERT) p.(Ala279Thr) was the most common DNA sequence variant identified among 435Research J P Dumanski et al. MUTYH substitution Gly396Asp in SI-NETs DOI: 10.1530/ERC-17-0196 http://.endocrinology-journals.org © 2017 The authors Printed in Great Britain Publish ~~~
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Review:
- Alfred King-yin Lam and
- Nassim Saremi
Cribriform-morular variant of papillary thyroid carcinoma: a distinctive type of thyroid cancer Endocr Relat Cancer 24 (4) R109-R121, doi:10.1530/ERC-17-0014
...telomerase reverse transcriptase ) is also commonly studied in papillary thyroid carcinoma as a prognostic indicator ( Vinagre et al . 2013 , Melo et al . 2014 ). P13K/Akt pathway is activated by either the loss of PTEN expression or a PIK3CA mutation, resulting in downstream β-catenin activation. I ~~~
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Review:
- Samantha Peiling Yang and
- Joanne Ngeow
Familial non-medullary thyroid cancer: unraveling the genetic maze Endocr Relat Cancer 23 (12) R577-R595, doi:10.1530/ERC-16-0067
...telomerase reverse transcriptase (TERT) and the telomerase RNA complex. At the end of a chromosome, the shelterin complex binds to the telomere and regulates the telomerase activity. It is composed of 6 proteins: telomere repeat-binding factor 1 (TRF1), TRF2, TRF1-interacting nuclear factor 2 (TIN2) ~~~
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Review:
- Vincenzo Marotta,
- Concetta Sciammarella,
- Annamaria Colao,
- and Antongiulio Faggiano
Application of molecular biology of differentiated thyroid cancer for clinical prognostication Endocr Relat Cancer 23 (11) R499-R515, doi:10.1530/ERC-16-0372 first published on 30 August 2016
...telomerase reverse transcriptase (TERT) and the tumour suppressor TP53 are emerging as feasible tools for molecular prognostication of DTC. In the recent years, mutations of the TERT promoter, with the 1,295,228 C>T (C228T) and the 1,295,250 C>T (C250T) being the most commonly detected, have represe ~~~
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Research:
- Benjamin C Thomas,
- Jonathan D Kay,
- Suraj Menon,
- Sarah L Vowler,
- Sarah N Dawson,
- Laura J Bucklow,
- Hayley J Luxton,
- Thomas Johnston,
- Charlie E Massie,
- Michelle Pugh,
- Anne Y Warren,
- Peter Barker,
- Keith Burling,
- Andy G Lynch,
- Anne George,
- Johanna Burge,
- Marie Corcoran,
- Sara Stearn,
- Alastair D Lamb,
- Naomi L Sharma,
- Greg L Shaw,
- David E Neal,
- and Hayley C Whitaker
Whole blood mRNA in prostate cancer reveals a four-gene androgen regulated panel Endocr Relat Cancer 23 (10) 797-812, doi:10.1530/ERC-16-0287 first published on 30 August 2016
...telomerase reverse transcriptase messenger RNA as a novel tumor marker for hepatocellular carcinoma. Clinical Cancer Research 11 3205–3209. (doi:10.1158/1078-0432.CCR-04-1487) Office for National Statistics 2013 Prostate cancer: the most common cancer among men in England – 2010. London, UK: Office ~~~
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Research:
- Tae Hyuk Kim,
- Young-Eun Kim,
- Soomin Ahn,
- Ji-Youn Kim,
- Chang-Seok Ki,
- Young Lyun Oh,
- Kyunga Kim,
- Jae Won Yun,
- Woong-Yang Park,
- Jun-Ho Choe,
- Jung-Han Kim,
- Jee Soo Kim,
- Sun Wook Kim,
- and Jae Hoon Chung
TERT promoter mutations and long-term survival in patients with thyroid cancer Endocr Relat Cancer 23 (10) 813-823, doi:10.1530/ERC-16-0219 first published on 15 August 2016
...telomerase reverse transcriptase (TERT) promoter in 71% of melanoma genomes, and these somatic mutations enhanced promoter activity by two- to four-fold (Horn et al. 2013, Huang et al. 2013), which might immortalize proliferative cancer cells by maintaining telomere length (Vinagre et al. 2014). Sta ~~~
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Research:
- Xuguang Zhu,
- Dong Wook Kim,
- Li Zhao,
- Mark C Willingham,
- and Sheue-yann Cheng
SAHA-induced loss of tumor suppressor Pten gene promotes thyroid carcinogenesis in a mouse model Endocr Relat Cancer 23 (7) 521-533, doi:10.1530/ERC-16-0103 first published on 7 June 2016
...telomerase reverse transcriptase (Tert) gene, forward, 5′-CTGGCTGATGGACACATACG-3′; reverse, 5′-TGCTCCACACACTCTTACGG-3′. The numbers of positive droplets for the wild-type Pten gene and the control telomerase reverse transcriptase (Tert) gene were read with the QX200 droplet reader. The number of cop ~~~

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Endocrine-Related Cancer

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