Searching journal content for oncogene (as phrase) in full text.

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  1. Review:
    • Yulong Li and
    • William F Simonds
    Endocrine neoplasms in familial syndromes of hyperparathyroidism Endocr Relat Cancer 23 (6) R229-R247, doi:10.1530/ERC-16-0059 first published on 20 May 2016
    ...increases levels of c-Myc, a proto-oncogene, and established regulator of cell growth...mutation of tumor suppressors or proto-oncogenes. These tumors often have different malignant...monopartite nuclear localization signal. Oncogene 26 1213-1221. (doi: 10.1038...
  2. Research:
    • Régia Caroline Peixoto Lira,
    • Paola Fernanda Fedatto,
    • David Santos Marco Antonio,
    • Letícia Ferro Leal,
    • Carlos Eduardo Martinelli,
    • Margaret de Castro,
    • Silvio Tucci,
    • Luciano Neder,
    • Leandra Ramalho,
    • Ana Luiza Seidinger,
    • Izilda Cardinalli,
    • Maria José Mastellaro,
    • José Andres Yunes,
    • Silvia Regina Brandalise,
    • Luiz Gonzaga Tone,
    • Sonir Roberto Rauber Antonini,
    • and Carlos Alberto Scrideli
    IGF2 and IGF1R in pediatric adrenocortical tumors: roles in metastasis and steroidogenesis Endocr Relat Cancer 23 (6) 481-493, doi:10.1530/ERC-15-0426 first published on 16 May 2016
    ...reduces the p53 activity in higher pH levels (Wasserman et al. 2012). Interestingly, in response to cellular stress such as oncogene activation, the p53 can shutdown the IGF pathway, reducing IGF2 and IGF1R expression and the receptor tyrosine phosphorylation...
  3. Research:
    • Veronica Kalhori,
    • Melissa Magnusson,
    • Muhammad Yasir Asghar,
    • Ilari Pulli,
    • and Kid Törnquist
    FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion Endocr Relat Cancer 23 (5) 457-468, doi:10.1530/ERC-16-0050 first published on 2 March 2016
    ...JP, Hinkkanen A & Tornquist K 2009 Sphingosine kinase as an oncogene: autocrine sphingosine 1-phosphate modulates ML-1 thyroid...Heat-shock factor 2 is a suppressor of prostate cancer invasion. Oncogene 35 1770-1784. ( doi:10.1038/onc.2015.241 ) Dicitore...
  4. Research:
    • Toru Tateno,
    • Tae Nakano-Tateno,
    • Shereen Ezzat,
    • and Sylvia L Asa
    NG2 targets tumorigenic Rb inactivation in Pit1-lineage pituitary cells Endocr Relat Cancer 23 (5) 445-456, doi:10.1530/ERC-16-0013 first published on 5 April 2016
    ...predisposition, the mechanisms underlying the more common sporadic pituitary tumors rarely involve mutations of classical oncogenes or tumor suppressor genes and have yet to be elucidated (Asa Ezzat 2009, 2014, 2016, Asa 2011). In fact, the only consistent...
  5. Review:
    • Lisa M Butler,
    • Margaret M Centenera,
    • and Johannes V Swinnen
    Androgen control of lipid metabolism in prostate cancer: novel insights and future applications Endocr Relat Cancer 23 (5) R219-R227, doi:10.1530/ERC-15-0556 first published on 29 April 2016
    ...MA, Casas F & Fajas L 2013 Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. Oncogene 32 5101-5110. ( doi:10.1038/onc.2012.523 ) Gao S , Ye H, Gerrin S, Wang H, Sharma A, Chen S, Patnaik A...
  6. Research:
    • Jaesung (Peter) Choi,
    • Yu Zheng,
    • David J Handelsman,
    • and Ulla Simanainen
    Glandular epithelial AR inactivation enhances PTEN deletion-induced uterine pathology Endocr Relat Cancer 23 (5) 377-390, doi:10.1530/ERC-16-0039 first published on 16 March 2016
    ...induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research 58 5667-5672. Lian Z , De Luca P & Di...expression by androgen receptor in prostate and breast cancers. Oncogene 30 4327-4338. ( doi:10.1038/onc.2011.144 ) Wen...
  7. Research:
    • Lena Lapkina-Gendler,
    • Itai Rotem,
    • Metsada Pasmanik-Chor,
    • David Gurwitz,
    • Rive Sarfstein,
    • Zvi Laron,
    • and Haim Werner
    Identification of signaling pathways associated with cancer protection in Laron syndrome Endocr Relat Cancer 23 (5) 399-410, doi:10.1530/ERC-16-0054 first published on 18 April 2016
    ...Werner H 2012 Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer. Oncogene 31 2703-2714. ( doi:10.1038/onc.2011.447 ) Werner H & Bruchim I 2009 The insulin-like growth factor-I receptor...
  8. Research:
    • Graeme B Bolger,
    • Mariana F Bizzi,
    • Sergio V Pinheiro,
    • Giampaolo Trivellin,
    • Lisa Smoot,
    • Mary-Ann Accavitti,
    • Márta Korbonits,
    • and Antonio Ribeiro-Oliveira, Jr
    cAMP-specific PDE4 phosphodiesterases and AIP in the pathogenesis of pituitary tumors Endocr Relat Cancer 23 (5) 419-431, doi:10.1530/ERC-15-0205
    ...HJ, Ahlsten M et al. 2015 AIP inactivation leads to pituitary tumorigenesis through defective Galphai-cAMP signaling. Oncogene 34 1174-1184. ( doi:10.1038/onc.2014.50 ) Vargiolu M , Fusco D, Kurelac I, Dirnberger D, Baumeister R, Morra...
  9. Research:
    • Anne-Lise Lecoq,
    • Say Viengchareun,
    • Mirella Hage,
    • Jérôme Bouligand,
    • Jacques Young,
    • Audrey Boutron,
    • Philippe Zizzari,
    • Marc Lombès,
    • Philippe Chanson,
    • and Peter Kamenický
    AIP mutations impair AhR signaling in pituitary adenoma patients fibroblasts and in GH3 cells Endocr Relat Cancer 23 (5) 433-443, doi:10.1530/ERC-16-0041 first published on 14 April 2016
    ...HJ, Ahlsten M et al. 2014 AIP inactivation leads to pituitary tumorigenesis through defective Galphai-cAMP signaling. Oncogene . ( doi:10.1038/onc.2014.50 ) Vierimaa O , Georgitsi M, Lehtonen R, Vahteristo P, Kokko A, Raitila A, Tuppurainen...
  10. Review:
    • David Viola,
    • Laura Valerio,
    • Eleonora Molinaro,
    • Laura Agate,
    • Valeria Bottici,
    • Agnese Biagini,
    • Loredana Lorusso,
    • Virginia Cappagli,
    • Letizia Pieruzzi,
    • Carlotta Giani,
    • Elena Sabini,
    • Paolo Passannati,
    • Luciana Puleo,
    • Antonio Matrone,
    • Benedetta Pontillo-Contillo,
    • Valentina Battaglia,
    • Salvatore Mazzeo,
    • Paolo Vitti,
    • and Rossella Elisei
    Treatment of advanced thyroid cancer with targeted therapies: ten years of experience Endocr Relat Cancer 23 (4) R185-R205, doi:10.1530/ERC-15-0555
    ...cells. In 1986, the first activated oncogene was found in the DNA extracted from an...demonstrated the presence of the same activated oncogene in other instances of PTC and particularly...1997, Elisei et al. 2001). The oncogene of interest is RET, which lies on chromosome...
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