Searching journal content for mice (as phrase) in full text.

Displaying results 1-10 of 942
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  1. Research:
    • B Wan,
    • L Dai,
    • L Wang,
    • Y Zhang,
    • H Huang,
    • G Qian,
    • and T Yu
    Knockdown of BRCA2 enhances cisplatin and cisplatin-induced autophagy in ovarian cancer cells Endocr Relat Cancer ERC-17-0261, doi:10.1530/ERC-17-0261 first published on 24 October 2017
    ...with the Guide for the Care and Use of Laboratory Animals. In vivo effects 174 were tested in 2 trials. 5.0 10 NC/shBRCA2-transfected CAOV-3 cells were 175 subcutaneously injected into the left armpit of 4-week-old BALB/c nude mice (Ctr. Lab. 176 Anim., Chongqing Med. Univ.), with 5 animals in each group. CDDP ~~~
  2. Research:
    • Amruta Ashtekar,
    • Danielle Huk,
    • Alexa Magner,
    • Krista La Perle,
    • Xiaoli Zhang,
    • José I Piruat,
    • José López-Barneo,
    • Sissy M Jhiang,
    • and Lawrence S Kirschner
    Sdhd ablation promotes thyroid tumorigenesis by inducing a stem-like phenotype Endocr Relat Cancer 24 (11) 579-591, doi:10.1530/ERC-17-0229 first published on 19 September 2017
    ...into this process, we generated mice lacking the SDH subunit D (Sdhd) in the thyroid. We report that these mice develop enlarged thyroid glands with follicle hypellularity and increased proliferation. In vitro, human thyroid cell lines with knockdown of SDHD exhibit an enhanced migratory capability, despite ~~~
  3. Research:
    • Zhu Wang,
    • Dinglan Wu,
    • Chi-Fai Ng,
    • Jeremy Yuen-Chun Teoh,
    • Shan Yu,
    • Yuliang Wang,
    • and Franky Leung Chan
    Nuclear receptor profiling in prostatospheroids and castration-resistant prostate cancer Endocr Relat Cancer ERC-17-0280, doi:10.1530/ERC-17-0280 first published on 17 October 2017
    ...and harvested for expression assays. 143 Establishment of castration-resistant prostate cancer tumor xenografts 144 VCaP cells (2 10 cells/100 l mixed 1:1 in Matrigel) were injected subcutaneously into the 145 flanks of 6-8 week old intact male SCID mice and allowed to grow for 14 weeks totally. Host 146 ~~~
  4. Review:
    • Priscilla Cukier,
    • Fernando C Santini,
    • Mariana Scaranti,
    • and Ana O Hoff
    Endocrine side effects of cancer immunotherapy Endocr Relat Cancer ERC-17-0358, doi:10.1530/ERC-17-0358 first published on 12 October 2017
    ...mice in adulthood. Proceedings of the National Academy of Sciences113 716 E2383-E2392. 717 Ku GY, Yuan J, Page DB, Schroeder SE, Panageas KS, Carvajal RD, Chapman PB, Schwartz GK, 718 Allison JP & Wolchok JD 2010 Single-institution experience with ipilimumab in 719 advancedmelanoma patients in the c ~~~
  5. Research:
    • Keren Cohen,
    • Uri Abadi,
    • Aleck Hercbergs,
    • Paul J Davis,
    • Martin Ellis,
    • and Osnat Ashur-Fabian
    The induction of myeloma cell death and DNA damage by tetrac, a thyroid hormone derivative Endocr Relat Cancer ERC-17-0246, doi:10.1530/ERC-17-0246 first published on 10 October 2017
    ...nongenomically initiated at the thyroid 378 hormone-tetrac receptor site on integrin v3 is at 10 to 10 M (Lin, et al. 2011). 379 The antagonistic effects were observed by tetrac in the myeloma cell models mainly at 380 high molar concentrations. However, no toxicity was detected in mice treated with up 381 ~~~
  6. Research:
    • Hongqiang Wang,
    • Rui Zhou,
    • Li Sun,
    • Jianling Xia,
    • Xuchun Yang,
    • Changqie Pan,
    • Na Huang,
    • Min Shi,
    • Jianping Bin,
    • Yulin Liao,
    • and Wangjun Liao
    TOP1MT deficiency promotes GC invasion and migration via the enhancements of LDHA expression and aerobic glycolysis Endocr Relat Cancer 24 (11) 565-578, doi:10.1530/ERC-17-0058 first published on 5 September 2017
    ...of TOP1MT on tumor metastasis was further demonstrated in vivo. All nude mice were treated according to ethical guidelines for the care and use of experimental animals. shTOP1MT and scramble control (5 106) GC cells (BGC-823 and SGC-7901 cell lines) were subcutaneously injected into the flanks ~~~
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  7. Review:
    • Maria Domenica Castellone and
    • Rosa Marina Melillo
    RET-mediated modulation of tumour microenvironment and immune response in MEN2 Endocr Relat Cancer ERC-17-0303, doi:10.1530/ERC-17-0303 first published on 20 September 2017
    ...ability of RET to induce IL8 production, Broutin and colleagues, identified IL8 as a 341 potential soluble biomarker of therapeutic response to Sunitinib in MTC patients 342 (Broutin, et al. 2011). 343 344 3.2.2 Mechanisms of immune surveillance in MTC 345 Studies in mice demonstrated that experimental ~~~
  8. Review:
    • Iuri Martin Goemann,
    • Mirian Romitti,
    • Erika L Souza Meyer,
    • Simone Magagnin Wajner,
    • and Ana Luiza Maia
    Role of thyroid hormones in the neoplastic process: an overview Endocr Relat Cancer 24 (11) R367-R385, doi:10.1530/ERC-17-0192
    ...) cells and breast cancer cells originally lacking TRs have shown that the reexpression of TR1 abolishes tumor growth and migration (Martinez-Iglesias et al. 2009) while preventing tumor formation by RAS-transformed cells in nude mice, even under hypothyroid conditions (Aranda et al. 2009 ~~~
  9. Review:
    • Robert C. Mould,
    • Jacob P. van Vloten,
    • Amanda W. K. AuYeung,
    • Khalil Karimi,
    • and Byram W. Bridle
    Immune response in the thyroid cancer microenvironment: making immunotherapy a possible mission Endocr Relat Cancer ERC-17-0316, doi:10.1530/ERC-17-0316 first published on 14 September 2017
    ...papillary thyroid cancer cells following 119 treatment of immunodeficient mice with IL-8 (Fang et al. 2014). However, a 120 retrospective study of patients with thyroid cancers found a favorable association 121 between the number of tumour-infiltrating macrophages and improved disease-free 122 Page 6 of 65 ~~~
  10. Thematic Review:
    • Zijie Feng,
    • Jian Ma,
    • and Xianxin Hua
    Epigenetic regulation by the menin pathway Endocr Relat Cancer 24 (10) T147-T159, doi:10.1530/ERC-17-0298 first published on 15 August 2017
    ...TRII, a vital component in TGF-beta signaling pathway, was deleted. Menin expression was also decreased in liver samples from the conditional TRIIknockout mice after TRII excision (Zhang et al. 2011). Wnt signaling Menin was shown to be crucial for regulating canonical Wnt/-catenin signaling ~~~
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