Supplementary Data

• Supplementary Figure 1 - Depict the mRNA expression and mutation status of VHL and EPAS1 genes among TCGA projects, including ccRCCs and PPGLs. Importantly, ccRCC and PPGL are the tumors with the highest expression of EPAS1 (HIF2A) and lowest expression of VHL.(PDF 2793 KB)
• Supplementary Figure 2 - Depict the mRNA expression and mutation status of VHL and EPAS1 genes among TCGA projects, including ccRCCs and PPGLs. Importantly, ccRCC and PPGL are the tumors with the highest expression of EPAS1 (HIF2A) and lowest expression of VHL. (PDF 1265 KB)
• Supplementary Figure 3 - Detailed expression and genetic data for ccRRC and PPGL samples. (PDF 1119 KB)
• Supplementary Figure 4 - Detailed expression and genetic data for ccRRC and PPGL samples. (PDF 1171 KB)
• Supplementary Table 1 - Somatic missense EPAS1 mutations identified in several cancer genomic projects from The Cancer Genome Atlas (TCGA), including PPGLs (here abbreviated as PCPG)(PDF 359 KB)
• Supplementary Table 2 - Localization of the somatic missense EPAS1 mutations identified in the TCGA projects (PDF 247 KB)